Results 11 to 20 of about 21,448 (228)

Familial Adenomatous Polyposis

Annals of Medicine, 1989
Familial adenomatous polyposis is an autosomal dominant disease that includes early development of up to thousands of colorectal adenomas and several extracolonic manifestations. All untreated patients will develop colorectal adenocarcinoma. The treatment of choice is colectomy and ileorectal anastomosis, but restorative proctocolectomy may be ...
Bülow, Steffen
core   +6 more sources

Desmoid tumor in patients with familial adenomatous polyposis [PDF]

Arquivos de Gastroenterologia, 2010
CONTEXT: Desmoid tumors constitute one of the most important extraintestinal manifestations of familial adenomatous polyposis. The development of desmoids is responsible for increasing morbidity and mortality rates in cases of familial adenomatous ...
Raquel Franco Leal, Patricia V. V. Tapia Silva, Maria de Lourdes Setsuko Ayrizono, João José Fagundes, Eliane M. Ingrid Amstalden, Cláudio Saddy Rodrigues Coy   +5 more
doaj   +2 more sources

Giant adrenal cavernous hemangioma in a patient with familial adenomatous polyposis

Clinics and Practice, 2016
Adrenal hemangioma is an uncommon benign vascular tumor that is often discovered incidentally. It has never been reported in association with familial adenomatous polyposis.
Dhouha Bacha, Abir Chaabane, Fatma Khanchel, Saloua Néchi, Hassen Touinsi, Emna Chelbi   +5 more
doaj   +2 more sources

Adult pancreatoblastoma with atypical histological morphology combined with familial adenomatous polyposis: a rare case report [PDF]

Frontiers in Oncology
Pancreatoblastoma (PB) is a rare malignant pancreatic epithelial tumor that mostly occurs in children and occasionally occurs in adults. The tumor has acinar cell differentiation and squamous corpuscles/squamous epithelial islands, which are frequently ...
Ying-Xia Wang, Su-Su Fan, Xue-Rong Peng, Yu-Shan Zhu, Xuan Zhang   +4 more
doaj   +2 more sources

Surgical complications and metachronous rectal cancer risk in patients with classic familial adenomatous polyposis

Journal of Coloproctology, 2015
Introduction: Familial adenomatous polyposis (FAP), an autosomal dominant disease characterized by development of numerous adenomatous polyps in the colon and rectum, is caused by germline mutations in the Adenomatous Polyposis Coli (APC) gene.
Paulo Roberto Stevanato Filho, Samuel Aguiar, Jr., Fábio O. Ferreira, Wilson T. Nakagawa, Ranyell M. Spencer, Renata M. Takahashi, Tiago S. Bezerra, Ademar Lopes   +7 more
doaj   +2 more sources

A Two Generation of Familial Adenomatous Polyposis

The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy, 2020
Familial adenomatous polyposis (FAP) is a part of genetic polyposis syndrome which is caused by germline mutation in the adenomatous polyposis coli (APC) gene located in chromosome 5q21. The pathognomonic features is formation of hundreds to thousands of
Lily Chandrawati, I Dewa Nyoman Wibawa
doaj   +3 more sources

The genetic basis of familial adenomatous polyposis and its implications for clinical practice and risk management

The Application of Clinical Genetics, 2015
Maria Liz Leoz, Sabela Carballal, Leticia Moreira, Teresa Ocaña, Francesc Balaguer Department of Gastroenterology, Hospital Clínic, Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas ...
Leoz ML, Carballal S, Moreira L, Ocaña T, Balaguer F   +4 more
doaj   +1 more source

Pathogenic APC Variants in Latvian Familial Adenomatous Polyposis Patients [PDF]

Medicina, 2019
Background and objectives: Familial adenomatous polyposis is one of the APC-associated polyposis conditions described as genetically predetermined colorectal polyposis syndrome with a variety of symptoms.
Zanda Daneberga, Dace Berzina, Viktors Borosenko, Zita Krumina, Linda Kokaine-Sapovalova, Andris Gardovskis, Egija Berga-Svitina, Janis Gardovskis, Edvins Miklasevics   +8 more
doaj   +2 more sources

Risk of extracolonic malignancies and metachronous rectal cancer after colectomy and ileorectal anastomosis in familial adenomatous polyposis

Asian Journal of Surgery, 2022
Background: Analysis of long-term clinical outcomes of patients with familial adenomatous polyposis is critical in reducing or preventing the incidence of extracolonic malignancies after initial surgery.
Kazuhito Sasaki, Hiroaki Nozawa, Kazushige Kawai, Koji Murono, Shigenobu Emoto, Junko Kishikawa, Hiroaki Ishii, Yuichiro Yokoyama, Shinya Abe, Yuzo Nagai, Hiroyuki Anzai, Hirofumi Sonoda, Tetsuro Taira, Soichiro Ishihara   +13 more
doaj   +1 more source

Large Rearrangements in Genes Responsible for Familial Adenomatous Polyposis, MUTYH-Associated Polyposis and Peutz–Jeghers Syndrome in Russian Patients

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2023
Аim: to reveal the rate of large rearrangements in the genes responsible for familial adenomatous polyposis, MUTYH-associated polyposis and Peutz–Jeghers syndrome.Materials and methods. The MLPA method was used for identification of large rearrangements.
A. N. Loginova, Yu. A. Shelygin, V. P. Shubin, A. M. Kuzminov, D. Yu. Pikunov, T. A. Saveleva, A. S. Tsukanov   +6 more
doaj   +1 more source