BJS (British Journal of Surgery), EarlyView., 2020 Recommendations for clinical and molecular identification of LS, surgical and endoscopic management of LS‐associated colorectal cancer and preventive measures for cancer were produced. The emphasis was on surgical and gastroenterological aspects of the cancer spectrum.
T. T. Seppälä +18 more
wiley +1 more source
Gene expression analyses on skin lesions from patients with familial adenomatous polyposis [PDF]
, 2014 Familial adenomatous polyposis coli (FAP) is an autosomal dominant colorectal cancer predisposition syndrome caused by germline mutations in the APC gene.
Stegmann, Danielle Alexandra
core +1 more source
Hereditary colorectal cancer : assessment of genotype-phenotype correlations and analysis of rare susceptibility genes in familial adenomatous polyposis (FAP) and hereditary nonpolyposis colorectal cancer (HNPCC) [PDF]
, 2008 Each year 3500 people in Switzerland are diagnosed with colorectal cancer. Approximately 20 percent of all affected patients have two or more first or second-degree relatives with colorectal cancer (at-risk family members). About five percent of these
Necker, Judith
core +1 more source
Attenuated Familial Adenomatous Polyposis
Internal Medicine, 2023 A 36-year-old man was diagnosed with multiple gastric polyps by esophagogastroduodenoscopy. Subsequent colonoscopy identified two tubular adenomas, and computed tomography revealed subcutaneous tumors. Based on these findings, we suspected that gastric polyposis was associated with the APC gene, either attenuated familial adenomatous polyposis (AFAP ...
Eizuka, Makoto +8 more
openaire +2 more sources
Serrated Polyposis Syndrome: A Literature Review
Journal of Coloproctology, 2023 Serrated polyposis syndrome is considered the most prevalent colonic polyposis syndrome in the world. Its importance has been increasingly discussed due to the significant increase in the risk of developing colorectal cancer in its affected individuals ...
Guilherme Campos Stephanini +3 more
doaj +1 more source
Screening for familial adenomatous polyposis [PDF]
Archives of Disease in Childhood, 2001 When a serious genetic disorder is diagnosed in the family, an immediate question arises: are other family members at risk? Ethical issues arise when DNA technology allows testing of children for a condition which is unlikely to have significant morbidity until later life. Familial adenomatous polyposis (FAP) exemplifies this dilemma.
W, Hyer, J M, Fell
openaire +2 more sources
Familial adenomatous colorectal polyposis complicated by colonic obturation: a clinical case
Кубанский научный медицинский вестник, 2020 Background. Colorectal obturation is a fairly rare complication in patients with colorectal polyposis. Case descriptions of colonic obturation with underlying familial adenomatous colorectal polyposis have not been reported to date in national and ...
V. M. Durleshter +3 more
doaj +1 more source
Familial adenomatous polyposis and hypertension [PDF]
The Lancet, 2010 In October, 2008, a 36-year-old man was referred to our unit with new onset of hypertension and adrenal hyperplasia. He had been diagnosed with familial adenomatous polyposis (FAP) in childhood, and had undergone a total colectomy at the age of 17 years. He had been under endoscopic surveillance since, with a recent polyp count of 50–60 (March).
Hopkins, TG +5 more
openaire +3 more sources
Identification of novel germline mutations in hereditary colorectal cancer patients and characterization of somatic alterations in their tumors [PDF]
, 2008 Colorectal cancer has been reported as the third leading cause of cancer related death in the world. About 5-10% of colorectal cancers are due to an inherited predisposition.
Zhang, Jian
core +1 more source
Familial adenomatous polyposis (FAP) [PDF]
, 1998 Review on Familial adenomatous polyposis (FAP), with data on clinics, and the genes ...
Olschwang, S
core +1 more source