Results 21 to 30 of about 18,649 (196)
“De novo” familial adenomatous polyposis (FAP) presenting as rectal cancer
Clinical Case Reports, 2021 Familial adenomatous polyposis is an autosomal dominant disorder with familial predisposition. 25%‐30% cases arise "de novo," without any clinical or genetic evidence.
Riya Agrawal, Utpal De
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Journal of Medical Case Reports, 2011 Introduction Ileal adenomas associated with familial adenomatous polyposis are a common finding. Many recent studies following panproctocolectomy for familial adenomatous polyposis have confirmed the presence of multiple ileal adenomas and an increase in
Hammad Ahmed +3 more
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Desmoids in familial adenomatous polyposis
Journal of British Surgery, 1996 Abstract Clinical desmoid disease affects approximately 10 per cent of patients with familial adenomatous polyposis (FAP); the subclinical rate is unknown. Desmoids are probably neoplastic rather than regenerative in origin and may arise in association with germline or somatic mutations at or beyond codon 1444 of the APC gene.
S K, Clark, R K, Phillips
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Chemoprevention in familial adenomatous polyposis [PDF]
Best Practice & Research Clinical Gastroenterology, 2011 Familial adenomatous polyposis (FAP) predictably leads to adenomas and eventual adenocarcinomas in the lower gastrointestinal tract and less frequently, the upper gastrointestinal tract. Chemopreventive strategies have been studied in FAP patients to delay the development of adenomas in the upper and lower gastrointestinal tract, as well as to prevent ...
Brian, Kim, Francis M, Giardiello
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Frontiers in OncologyPancreatoblastoma (PB) is a rare malignant pancreatic epithelial tumor that mostly occurs in children and occasionally occurs in adults. The tumor has acinar cell differentiation and squamous corpuscles/squamous epithelial islands, which are frequently ...
Ying-Xia Wang +4 more
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Familial adenomatous polyposis in China
Oncology Letters, 2016 Familial adenomatous polyposis (FAP) is an autosomal dominant disease with a poor prognosis, and has been studied by clinicians and geneticists in China for the past three decades. It is estimated that FAP has an incidence of between 1 in 8,000 and 1 in 10,000 individuals, and accounts for 0.94% of colorectal cancer cases in China.
Jun, Yang +5 more
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Familial adenomatous polyposis of the colon [PDF]
Hereditary Cancer in Clinical Practice, 2013 Abstract Familial adenomatous polyposis (FAP) is a well-defined autosomal dominant predisposition to the development of polyposis in the colon and rectum at unusually early ages. The first symptoms of FAP are diarrhea and blood in the stool. Weight loss and weaknesses occur after the development of advanced tumour.
Plawski, Andrzej +6 more
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
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Familial polyposis coli: the management of desmoid tumor bleeding
Open Medicine, 2019 There is currently no standard treatment for desmoid tumors (DTs) associated with familial polyposis coli (FAP). Familial adenomatous polyposis in DT patients is sometimes a life-threatening condition.
Calogero Armando +11 more
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Journal of Coloproctology, 2015 Introduction: Familial adenomatous polyposis (FAP), an autosomal dominant disease characterized by development of numerous adenomatous polyps in the colon and rectum, is caused by germline mutations in the Adenomatous Polyposis Coli (APC) gene.
Paulo Roberto Stevanato Filho +7 more
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