Results 151 to 160 of about 19,814 (246)

FXR‐Mediated Atherosclerosis Alleviation by B. animalis F1‐7 Through Bile Acid Metabolism‐Driven Gut–Liver Axis Modulation

Food Frontiers, Volume 7, Issue 2, March 2026.
ABSTRACT This study investigates the mechanisms of B. animalis F1‐7 improving atherosclerosis (AS) through bile acid metabolism by using an “antibiotic cocktail” approach in AS model mice. It was found that B. animalis F1‐7 could effectively reduce lipid accumulation in the aorta of mice, alleviate inflammatory responses and improve the intestinal ...
Tianhu Shan, Jiawen Wang, Yanyang Liu, Huaqi Zhang, Zhe Zhang, Lanwei Zhang, Hui Liang, Xi Liang   +7 more
wiley   +1 more source

The Genetic Landscape of Familial Hypercholesterolemia in Telangana, Southern India: Novel Mutations and Clinical Implications. [PDF]

Cureus
Garapati S, Varatharajan S, K A, Yadav K, Saluja R, Yellaboina S.   +5 more
europepmc   +1 more source

Association Between Ketogenic Diet and Overactive Bladder: The Mediating Roles of Dietary Inflammatory Index and Weight‐Adjusted Waist Index

Food Science &Nutrition, Volume 14, Issue 3, March 2026.
Higher dietary ketogenic ratio was associated with lower prevalence of overactive bladder, partially mediated by dietary inflammation and central adiposity in U.S. adults (NHANES 2009–2018). ABSTRACT Overactive bladder (OAB) is characterized by urinary urgency, often accompanied by increased frequency and nocturia, and is associated with impaired ...
Xuefeng Jin, Tong Zhang, Hao Li, Jie Wang, Shiquan Xu, Jingping Ge, Zizhi Li, Xiangrui Kong, Junlin Chen, Xuejiao Wen, Wenhui Tong, Xiaoyan Liu, Hangxu Li   +12 more
wiley   +1 more source

Effect of L‐Citrulline Intake on Blood Pressure in Cold Environments: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

Food Science &Nutrition, Volume 14, Issue 3, March 2026.
This study investigated the effect of L‐citrulline supplementation on BP under cold exposure and found that it significantly reduced both SBP and DBP, thereby alleviating cold‐induced hypertension, thus providing a scientific basis for cardiovascular protection. Future studies should further investigate its optimal dosage.
Ping Luo, Jingfeng Chen, Kang Liu, Jia Zhang   +3 more
wiley   +1 more source

Population Genomic Screening and Improved Lipid Management in Patients With Familial Hypercholesterolemia. [PDF]

Circ Genom Precis Med
Levy ME, Schiabor Barrett KM, Betts MN, Kann D, Bolze A, Khuder B, Telis N, McEwen LM, Sturm AC, Haldeman-Englert C, Cauwels J, Stoller D, Chahal CAA, Chapman CN, Waring AA, Olson DA, Grzymski JJ, Washington NL, Lee W, Cirulli ET, Hajek C.   +20 more
europepmc   +1 more source

Cardiovascular Disease Knowledge Amongst Jordanian Population: A Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Aim Cardiovascular diseases are the leading cause of death in both developed and developing countries, causing significant healthcare system disruptions due to inadequate access, high costs, and growing complications. This study aims to examine cardiovascular knowledge comprehensively among the Jordanian population.
Ahmed Mohammad Al‐smadi, Salam Bani Hani, Hossam Alhawatmeh, Rula Amr, Omar gammoh, Abedalmajeed Shajrawi, Ala Ashour, Rani Shatnawi., Donna Fitzsimons, Albara Alomari   +9 more
wiley   +1 more source

Treatment of Homozygous Familial Hypercholesterolemia. [PDF]

JACC Adv
Cegla J, Walji S, Barton L, Neuwirth C, Thompson GR.   +4 more
europepmc   +1 more source

RNA‐Based Therapies for Inherited Metabolic Disorders

Journal of Inherited Metabolic Disease, Volume 49, Issue 2, March 2026.
ABSTRACT Inherited metabolic disorders (IMDs) are a diverse and complex group of genetic conditions resulting from deficiencies in enzymes, transporters, or cofactors. These deficiencies lead to metabolic dysfunction and severe clinical consequences. Despite significant progress in understanding their molecular basis, treatment options remain limited ...
Reddy Sreekanth Vootukuri, Sonam Gurung, Roopkatha Ghosh, Philippa B. Mills, Julien Baruteau, Haiyan Zhou   +5 more
wiley   +1 more source

Variable phenotype associated with compound LDLR gene mutations in familial hypercholesterolemia patients: Case series and clinical implications. [PDF]

Medicine (Baltimore)
Mohd Kasim NA, Chua YA, Sheikh Abdul Kadir SH, Al-Khateeb A, Razman AZ, Nazli SA, Kamal A, Kanchau JD, Lee YS, Mohamed Yassin MS, Qureshi N, Nawawi H, Ramli AS.   +12 more
europepmc   +1 more source

Efficacy and Safety of DNV3 (a Lymphocyte‐activation Gene 3–blocking Antibody) Combined With Toripalimab and Chemotherapy in Advanced Melanoma: An Open‐label, Single‐arm Clinical Trial

MedComm, Volume 7, Issue 3, March 2026.
This investigator‐initiated trial demonstrates that LAG‐3/PD‐1 dual blockade (DNV3 + toripalimab) combined with chemotherapy achieves a 44.4% overall response rate (ORR) in advanced melanoma, showing particular efficacy in anti‐PD‐(L)1‐resistant patients (42.9% ORR, 7.36‐month median PFS), treatment‐naïve mucosal melanoma (50.0% ORR), and those with ...
Jing Lin, Lizhu Chen, Ling Chen, Dingyi Wang, Yuping Lu, Huishan Zhang, Ping Chen, Wei Yan, Zuoxiang Xiao, Yu Chen   +9 more
wiley   +1 more source