Results 171 to 180 of about 234,426 (253)

Machine learning predictors of post‐radiotherapy cardiotoxicity in a Latin American breast cancer cohort: Clinical risk factors outperform cardiac dosimetry

Journal of Applied Clinical Medical Physics, Volume 27, Issue 10, October 2026.
Abstract Background Most evidence on post‐radiotherapy cardiotoxicity (CDT) derives from Global North cohorts, and the relative contribution of baseline clinical risk versus cardiac dosimetry remains poorly characterized in Latin American populations.
Víctor Aguirre‐Bravo, Rodrigo El Far, María Herrera Ruiz, Sophia Gálvez Santelices, Pablo Munoz‐Schuffenegger, Tomás Merino, Sergio Diez Domingo, Marcelo E. Andia   +7 more
wiley   +1 more source

Using Implementation Science to Improve Guidelines-Based Care to Lower Atherosclerosis Risk Due to Familial Hypercholesterolemia. [PDF]

Curr Atheroscler Rep
Hallquist MLG, Brangan A, Cawley D, Gabriel JL, Kunnmann M, Ly K, Morales A, Romagnoli K, Savatt JM, Walters NL, Gidding SS.   +10 more
europepmc   +1 more source

Reorganization of Innate Immune Cell Lipid Profiles by Bioinspired Meroterpenoids to Limit Inflammation

Advanced Science, Volume 13, Issue 59, 23 October 2026.
Resolution pharmacology is an emerging strategy to tackle inflammatory pathologies. Bioinspired meroterpenoids induce a lipid mediator class switch toward inflammation resolution in vitro and in vivo by targeting key nodes in lipid mediator biosynthesis and neutral lipid dynamics.
Lorenz Waltl, David Holubek, Klaus Speck, Raphael Wildermuth, Franz‐Lucas Haut, Stephan Permann, Immanuel Plangger, Christian Steinborn, Zhigang Rao, Danilo D'Avino, Ida Cerqua, Julia Stadler, Fiorentina Roviezzo, Peter Schlenke, Anita Siller, Harald Schennach, Solveigh C. Koeberle, Eva‐Maria Pferschy‐Wenzig, Antonietta Rossi, Thomas Magauer, Andreas Koeberle   +20 more
wiley   +1 more source

Familial Hypercholesterolemia

Gomal Journal of Medical Sciences, 2004
Sheikh Muhammad Nazir
doaj  

Proposal of a familial hypercholesterolemia paediatric diagnostic score (FH-PeDS). [PDF]

Eur J Prev Cardiol
Kafol J, Miranda B, Sikonja R, Sikonja J, Wiegman A, Medeiros AM, Alves AC, Freiberger T, Hutten BA, Mlinaric M, Battelino T, Humphries SE, Bourbon M, Groselj U.   +13 more
europepmc   +1 more source

Defining Features of Gabriele‐de Vries Syndrome in Adults: A Case Report and Literature Review

American Journal of Medical Genetics Part A, Volume 200, Issue 10, Page 2396-2404, October 2026.
ABSTRACT Gabriele‐de Vries syndrome (GADEVS) is a neurodevelopmental disorder caused by heterozygous pathogenic variants in the YY1 gene. Like most rare genetic syndromes, the adult manifestations of GADEVS remain poorly defined. Here, we describe the oldest patient reported to date with GADEVS—a 63‐year‐old woman with a c.1177_1179del YY1 variant ...
Ethan W. Hollingsworth, Changrui Xiao
wiley   +1 more source

Extracellular vesicles related to familial hypercholesterolemia. [PDF]

Arch Endocrinol Metab
Silvino JPP, Jannes CE, Pestana RMC, Silvino LPP, Silva IFO, Teixeira-Carvalho A, Gomes KB.   +6 more
europepmc   +1 more source

Genetic Risk and High Burden of Depression and Suicide in the Maya‐Mestizo Population of Yucatán, México

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Volume 201, Issue 7, Page 431-440, October 2026.
ABSTRACT Major depression and suicide are critical public health concerns, particularly in underrepresented populations with unique genetic and sociocultural contexts. The Maya‐mestizo population presents the highest suicide rates in the country but remains understudied in psychiatric genetics. This study evaluated the association between three genetic
Marta Menjivar, Erandi Bravo, Margarita Rivera‐Balancan, Barbara Itzel Pena Espinoza   +3 more
wiley   +1 more source

Opportunistic Genetic Testing for Familial Hypercholesterolemia in Premature Acute Coronary Syndrome: Results of the ACCURATE Study. [PDF]

JACC Adv
Vaizman N, Cermakova L, Cooper M, Kramer AI, Hui K, Jackson LM, Roston TM, Mancini GBJ, Fordyce CB, Iatan I, Brunham LR.   +10 more
europepmc   +1 more source

GLP‐1R agonist semaglutide protects human forebrain organoids from cholesterol‐induced neurotoxicity

Alzheimer's &Dementia, Volume 22, Issue 10, October 2026.
Abstract INTRODUCTION Dysregulated cholesterol metabolism represents a critical metabolic stressor in the central nervous system, contributing to neuronal injury across multiple neurological conditions, including Alzheimer's disease (AD). While glucagon‐like peptide‐1 receptor (GLP‐1R) agonists show neuroprotective potential, their capacity to directly
Feifei Yu, Jiani Xu, Yibo Hou, Honghui Zheng, Lingyi Guo, Davit Khutsishvili, Cheng Hai, Wenxin Xu, Bailing Chen, Zitian Wang, Shaohua Ma   +10 more
wiley   +1 more source