Results 161 to 170 of about 234,426 (253)

Health-Related Quality of Life in Homozygous Familial Hypercholesterolemia: Results from an Online Survey. [PDF]

Patient Prefer Adherence
Evans E, Lichaa C, Jones RD, Wiegman A, Daccord M.   +4 more
europepmc   +1 more source

Paraneoplastic and Autoimmune Retinopathy Presenting as Isolated Neuro‐Ophthalmic Dysfunction: Two Cases

Clinical and Experimental Neuroimmunology, Volume 17, Issue 4, November 2026.
ABSTRACT Background Paraneoplastic and autoimmune retinopathies can cause progressive visual loss before structural ophthalmic or neurologic findings are diagnostic. Case Presentation A 66‐year‐old woman developed bilateral visual decline and was diagnosed with small‐cell lung cancer‐associated paraneoplastic neuroretinal dysfunction, with persistent ...
Alan B. Dogan, Dean Neutel, Anthony L. Loschner   +2 more
wiley   +1 more source

Understanding Barriers and Motivators of Familial Hypercholesterolemia Genetic Testing: Insights From the Singapore Public. [PDF]

J Genet Couns
Quek DSR, Yin R, Chan FHF, Nastar A, Ngeow J, Pek S, Savulescu J, Subramaniam T, Griva K.   +8 more
europepmc   +1 more source

Diffusely impaired myocardial perfusion in patients with suspected coronary artery disease: Clinical utility of relative perfusion

Clinical Physiology and Functional Imaging, Volume 46, Issue 6, November 2026.
Abstract Background In patients with suspected coronary artery disease (CAD), diffusely impaired hyperaemic myocardial blood flow (MBF) may indicate a multivessel epicardial CAD but also impaired coronary microcirculation. We assessed whether relative hyperaemic MBF—that is, the ratio of the lowest to the highest regional hyperaemic MBF—predicts ...
Niklas Vartiainen, Antti‐Pekka E. Rissanen, Suvi Hartikainen, Svantte Halttunen, Aleksi J. Leikas, Elina Kariniemi, Eero Strengell, Paavo‐Ilari Kuikka, Juha E. K. Hartikainen, Tomi P. Laitinen   +9 more
wiley   +1 more source

Clinical characteristics and in‐hospital mortality among insulin pump users with acute coronary syndrome in the predominantly open‐loop era: A UK‐wide MINAP registry analysis

Diabetic Medicine, Volume 43, Issue 11, November 2026.
Abstract Background We compared characteristics of adults with insulin‐treated diabetes using continuous subcutaneous insulin infusion (CSII) versus multiple daily insulin injections (MDI) during admission with acute coronary syndrome (ACS) and identified factors associated with in‐hospital mortality among CSII users.
Harshal Deshmukh, Moosa Shaikh, Emma G. Wilmot, Eric Kilpatrick, Sudipta Chattopadhyay, Thozhukat Sathyapalan, Joseph John   +6 more
wiley   +1 more source

Putative protective role of <i>PCSK9</i> variants in a multigenerational family with familial hypercholesterolemia. [PDF]

Atheroscler Plus
Rodríguez-Nóvoa S, Martínez Hernández P, Hidalgo Mayoral I, Herranz Cecilia A, Rodríguez Roca N, Carazo Álvarez A, Gallego Onís N, Duque Alcorta M, Rodríguez Jiménez C.   +8 more
europepmc   +1 more source

Hypocholesterolemia in liver and cardiovascular disease: Friend or foe?

Journal of Internal Medicine, Volume 300, Issue 5, Page 572-589, November 2026.
Abstract Hypocholesterolemia is perceived as benign given its association with lower cardiovascular risk. However, genetic and epidemiological evidence indicates that persistently low levels of low‐density lipoprotein cholesterol (LDL‐C) and apolipoprotein B (ApoB) arise from distinct biological mechanisms with different hepatic implications ...
Valentina Flagiello, Emelie Barreby, Umberto Vespasiani‐Gentilucci, Stefano Romeo   +3 more
wiley   +1 more source

Clinical Benefits Associated With Evinacumab in Pediatric Patients With Homozygous Familial Hypercholesterolemia. [PDF]

J Am Heart Assoc
Reijman MD, Nigmann C, Kusters DM, Planken RN, Loewe C, Verpalen VA, Hovingh GK, Neyer M, Draxler-Dworzak S, Mair K, Arbeiter K, Mueller-Sacherer T, Groothoff JW, Hutten BA, Greber-Platzer S, Wiegman A.   +15 more
europepmc   +1 more source

NSG Mice Lacking Apoe: An Immunodeficient Mouse Model of Atherosclerosis

The FASEB Journal, Volume 40, Issue 20, 31 October 2026.
Immunodeficient NSG mice lacking the Apoe gene develop atherosclerosis when placed on high fat diet (HFD). These mice support engraftment with human CD34+ hematopoietic stem cells. The NSG‐ApoEKO mice can be used in humanized mouse models to examine human‐specific immune disease mechanisms. Created in BioRender.
Hannah R. Megathlin, Lisa Burzenski, David A. Coleman, Blaze Albert, Michelle L. Farley, Michael A. Brehm, Dale L. Greiner, Leonard D. Shultz   +7 more
wiley   +1 more source

Carpe Diem: Genetic Testing for Familial Hypercholesterolemia From Acute Coronary Care to the Community. [PDF]

JACC Adv
Pang J, Rosenson RS, Wilkinson MJ, Kalra DK, Watts GF.   +4 more
europepmc   +1 more source