Results 181 to 190 of about 224,441 (293)

Child-parent screening for familial hypercholesterolaemia: screening strategy based on a meta-analysis [PDF]

, 2007
Bestwick, JP, Wald, NJ, Wald, DS
core   +1 more source

Leisure‐Time Physical Activity on Age‐Modelled Trajectories of Body Mass Index and Obesity Risk Throughout Life: Multivariable Regression and Mendelian Randomization Analyses Using Electronic Health Record Data From the CORDELIA‐Catalunya Study

Diabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 8925-8935, October 2026.
ABSTRACT Aims To assess whether self‐reported leisure‐time physical activity, moderate‐to‐vigorous leisure‐time physical activity, and genetically determined cardiorespiratory fitness are associated with age‐related BMI trajectories and incident obesity. Methods We pooled 14 993 adults (30–90 years; 52.7% women; cohorts: REGICOR‐ACRISC, ILERVAS, ARTPER)
Javier Hernando‐Redondo, Anna Camps‐Vilaró, Roberto Elosua, Eleonora Fornara, Marcelino Bermúdez‐López, Pere Torán‐Monserrat, Ainara Jiménez‐Navarro, José M. Valdivielso, Víctor M. López‐Lifante, Tomàs Salas‐Fernández, Serafí Cambray, Raquel Cruz, Jaume Marrugat, Álvaro Hernáez   +13 more
wiley   +1 more source

Opportunistic Genetic Testing for Familial Hypercholesterolemia in Premature Acute Coronary Syndrome: Results of the ACCURATE Study. [PDF]

JACC Adv
Vaizman N, Cermakova L, Cooper M, Kramer AI, Hui K, Jackson LM, Roston TM, Mancini GBJ, Fordyce CB, Iatan I, Brunham LR.   +10 more
europepmc   +1 more source

Genomic Medicine Sweden: Advancing precision medicine at the national level

Journal of Internal Medicine, Volume 300, Issue 4, Page 397-419, October 2026.
Abstract High‐throughput sequencing has transformed clinical diagnostics of rare diseases (RD), cancer and infectious diseases by enabling the identification of disease‐causing genetic alterations and facilitating individualised treatment and care.
Anders Edsjö, Anna Lindstrand, Panagiotis Baliakas, David Gisselsson, Paula Mölling, Mia Wadelius, Åsa Johansson, Hannes Olauson, Hans Ehrencrona, Lovisa Lovmar, Christian G. Giske, Henrik Green, Ann Nordgren, Fulya Taylan, Martin Hallbeck, Erika Tång Hallbäck, Anna Green, Markus Heidenblad, Kina Höglund, Anders Jemt, Carl Mårten Lindqvist, Maria Johansson Soller, Magnus Sabel, Colum Walsh, Hartmut Vogt, Craig E. Wheelock, Martin Bergö, Jens Enoksson, Ann Ekberg Jansson, Cecilia Fagerström, Jan Holgersson, Stephanie Anja Juran, Mats G. Karlsson, Frida Lundmark, Eva Tiensuu Janson, Andreas Muranyi Scheutz, Malin Sund, Päivi Östling, Sofia Gruvberger‐Saal, Marene Landström, Malin Melin, Lars Palmqvist, Richard Palmqvist, Bianca Stenmark, Anna Wedell, Malin Karnå, Katarina Nyström, Tobias Strid, Per Sikora, Maria Johansson, Therese Fagerqvist, Mirja Carlsson Möller, Oskar Frisell, Mats Ulfendahl, Mikaela Friedman, Lucia Cavelier, Valtteri Wirta, Thoas Fioretos, Richard Rosenquist   +58 more
wiley   +1 more source

Lipemia Retinalis in an Infant With a PCSK9 Variant of Familial Hypercholesterolemia: A Case Report. [PDF]

Cureus
Ismail AZ, Wong CL, Tai Li Min E.
europepmc   +1 more source

Efficacy of 0.5% Tretinoin in the Treatment of Equine Aural Plaques

Veterinary Dermatology, Volume 37, Issue 5, Page 664-671, October 2026.
Background: Equine aural plaques are a benign form of auricular papillomatosis caused by equine papillomavirus. Despite the efficacy of 5% imiquimod cream, a marked local reaction is frequently observed during therapy, often requiring sedation before application.
Felipe Sperandio de Mattos, Lissandro Gonçalves Conceição, Ytalo Galinari Henrique Schuartz, Vitória Régia Melo Silva, Cintia Fernandes Fidélis, Fernanda Campos Mansur, Cristian Silva Teixeira, Yame Fabres Robaina Sancler‐Silva, Jose Paes Oliveira‐Filho, Alexandre Secorun Borges, Cristiana Raach Bromberger, José Dantas Ribeiro Filho, Marcel Ferreira Bastos Avanza, José Ricardo Barboza Silva, Raffaella Bertoni Cavalcanti Teixeira   +14 more
wiley   +1 more source

Metabolic Shifts Precede Cognitive Decline in the Male hAß‐KI Alzheimer's Mouse Model

The FASEB Journal, Volume 40, Issue 17, 15 September 2026.
A major barrier in Alzheimer's disease (AD) research is the lack of animals that recapitulate sporadic AD. The humanized amyloid‐beta knock‐in mice (hAß‐KI) exhibit age‐dependent cognitive decline and beta‐amyloid accumulation. However, limited research has been conducted related to AD risk factors and sex‐specific responses.
Evelin Melekh, Emma L. Cook, Julia G. Stante, Amélie A. T. Marais, Ahmad Mohammad, Shawn M. Beaudette, Wendy E. Ward, Val A. Fajardo, Rebecca E. K. MacPherson   +8 more
wiley   +1 more source

Retinal findings in familial hypercholesterolemia: An exploratory case-control study. [PDF]

Atheroscler Plus
Langslet G, Kollstad S, Jørstad ØK, Erke MG, Retterstøl K, Holven KB.   +5 more
europepmc   +1 more source

Next‐Generation Manufacturing: The Evolving Role of Biocatalysis in AstraZeneca

ChemBioChem, Volume 27, Issue 17, 14 September 2026.
Biocatalysis is strengthening AstraZeneca's manufacture of active pharmaceutical ingredients through faster development, robust scale‐up, and lower environmental impact. Case studies illustrate where biocatalysis delivers greatest value, while enabling platforms, teams, and partnerships shape its next phase.
Alba Diaz‐Rodriguez, Martin A. Hayes, Keith R. Mulholland, Fernando Tur, Samantha Staniland   +4 more
wiley   +1 more source

Sitosterolemia misdiagnosed as homozygous familial hypercholesterolemia: A diagnostic challenge. [PDF]

Am J Prev Cardiol
Matta A, Nader V, Ferrières D, Ferrières J.   +3 more
europepmc   +1 more source