Results 181 to 190 of about 234,426 (253)

Aortic valve disease: Novel animal models for advancing our understanding of the underlying mechanisms

open access: yesAnimal Models and Experimental Medicine, Volume 9, Issue 10, Page 1964-1981, October 2026.
Due to the complex pathophysiology of aortic valve disease (AVD) and the resulting lack of effective pharmacotherapy, existing animal models are valuable research tools, but each has its own strengths and limitations. This review systematically surveys the major AVD models, compares their induction methods, pathological features, advantages and ...
Liya Hou   +4 more
wiley   +1 more source

Comparative Effectiveness of Intravenous Tenecteplase versus Alteplase in Posterior Circulation Ischemic Stroke: A Systematic Review and Meta‐Analysis

open access: yesBrain and Behavior, Volume 16, Issue 10, October 2026.
Visual summary of the comparative efficacy and safety of intravenous tenecteplase versus alteplase in posterior circulation ischemic stroke. ABSTRACT Background Posterior circulation ischemic stroke (PCIS) is associated with substantial morbidity and mortality, and the optimal intravenous thrombolytic strategy in this subgroup remains unclear.
Shaheer Bin Shafiq   +11 more
wiley   +1 more source

Advanced therapy in familial hypercholesterolemia. [PDF]

open access: yesCan Fam Physician
Gao E, Brunham LR, Goldman RD.
europepmc   +1 more source

Driver Gene Mutations Reprogram Lipid Metabolism in Non‐Small Cell Lung Cancer

open access: yesCancer Medicine, Volume 15, Issue 10, October 2026.
ABSTRACT Non‐small cell lung cancer (NSCLC) is among the leading causes of cancer‐related deaths worldwide. Previous treatment regimens often have limited efficacy due to drug resistance and recurrence. Metabolic reprogramming participates in the initiation and progression of NSCLC, with prominent changes in lipid metabolism.
Jinxing Lin   +3 more
wiley   +1 more source

Comparison of Immediate Versus Staged Complete Revascularization in Patients With Index PCI Coronary Complications: A Study on Clinical Outcomes and Predictors of Complications

open access: yesCatheterization and Cardiovascular Interventions, Volume 108, Issue 4, Page 1241-1247, October 1, 2026.
ABSTRACT Background In patients with acute coronary syndrome (ACS) and multivessel disease (MVD), complete revascularization (CR) improves clinical outcomes compared with culprit‐only percutaneous coronary intervention (PCI). However, the optimal timing of CR, immediate (ICR) versus staged (SCR), remains debated.
Alessandro Gabrielli   +7 more
wiley   +1 more source

Real-World Outcomes of Lipoprotein Apheresis in Homozygous Familial Hypercholesterolemia: A Single-Center Longitudinal Experience. [PDF]

open access: yesJ Clin Med
Mercan Sarıdaş F   +8 more
europepmc   +1 more source

Interaction of Operator−Patient Sex on Peri‐Procedural Treatments and Major Coronary Outcomes After Percutaneous Coronary Intervention

open access: yesCatheterization and Cardiovascular Interventions, Volume 108, Issue 4, Page 1520-1528, October 1, 2026.
ABSTRACT Background There are limited data evaluating the association between operator−patient sex, and outcomes in patients undergoing percutaneous coronary intervention (PCI). Methods We included 138,112 consecutive PCI procedures in patients presenting with acute coronary syndrome (ACS) in England and Wales, 2017−2020.
Sharon A. Ayayo   +6 more
wiley   +1 more source

Retinal findings in familial hypercholesterolemia: An exploratory case-control study. [PDF]

open access: yesAtheroscler Plus
Langslet G   +5 more
europepmc   +1 more source

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