Results 201 to 210 of about 224,441 (293)

Decoding Primary Hyperlipoproteinemias: A Focus on the Pathogenesis and Diagnosis of Familial Hypercholesterolemia and Familial Combined Hyperlipidemia. [PDF]

open access: yesDiagnostics (Basel)
Bararu-Bojan I   +12 more
europepmc   +1 more source

The Association Between Atherogenic Index of Plasma and Type 2 Diabetes Mellitus in a Multi‐Ethnic Population of Premature Coronary Artery Disease Patients: Insights From IPAD Study

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.
In patients with premature coronary artery disease, higher atherogenic index of plasma was associated with prevalent type 2 diabetes and higher fasting blood sugar. Exploratory analyses suggested possible ethnicity‐related heterogeneity, while ROC analysis showed limited discrimination, supporting cautious interpretation rather than clinical screening ...
Reza Amani‐Beni   +8 more
wiley   +1 more source

Mechanisms and Predisposing Conditions for Statin‐Induced New‐Onset Type 2 Diabetes Mellitus: A Paradox Relative to Their Pleiotropic Metabolic Effects

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.
The primary function of statins is to inhibit cholesterol synthesis, which contributes to their antidiabetic effects. However, the majority of the diabetic effects of statins are due to inhibition of isoprenoid synthesis. Atorvastatin, simvastatin and rosuvastatin possess the most pronounced diabetogenic properties. In contrast, lovastatin, fluvastatin,
Ali Nosrati Andevari, Mohsen Koolivand
wiley   +1 more source

Study on the in Vivo Cholesterol‐Lowering Effect of Galacto‐Oligosaccharides Synergized with Lactiplantibacillus plantarum BF_15 via Modulation of Gut Microbiota

open access: yesFood Frontiers, Volume 7, Issue 5, September 2026.
The synbiotic consisting of galacto oligosaccharides (GOS) and Lactiplantibacillus plantarum BF_15 mitigates hypercholesterolemia in high cholesterol diet fed mice. This synbiotic lowers serum TC, TG, and LDL C levels and ameliorates hepatic steatosis. It enriches gut microbes with bile salt hydrolase activity (e.g., Bifidobacterium) and SCFA producing
Na Zhang   +9 more
wiley   +1 more source

Validated Polygenic Risk Scores Complement Monogenic Testing in South Asian Patients With Familial Hypercholesterolemia. [PDF]

open access: yesJACC Asia
Abraham N   +13 more
europepmc   +1 more source

Therapeutic Effects and Mechanisms of Fucoidan on Dyslipidemia in Obese Mice

open access: yesFood Science &Nutrition, Volume 14, Issue 9, September 2026.
In the present study, fucoidan (50 mg/kg/day) did not alter HFD‐driven weight gain or food intake, but significantly decreased serum total cholesterol (TC). Fucoidan reduced hepatic triglyceride, TC, and lipid droplets, improving hepatic lipid accumulation.
Lizhi Peng   +8 more
wiley   +1 more source

Bergamot (Citrus bergamia) Supplementation and Cardiovascular Disease Risk Factors: A Systematic Review and Meta‐Analysis

open access: yesFood Science &Nutrition, Volume 14, Issue 9, September 2026.
Summary of the systematic review and meta‐analysis of randomized controlled trials evaluating the effects of bergamot (Citrus bergamia) supplementation on cardiometabolic risk factors in adults. ABSTRACT Cardiovascular diseases remain the leading cause of global mortality.
Mahla Chambari   +7 more
wiley   +1 more source

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