Results 211 to 220 of about 234,426 (253)

Genetic screening and response to drug therapy in familial hypercholesterolemia. [PDF]

Front Mol Biosci
Lu Y, Chen Q, Zhang W, Dong J, Zha L.
europepmc   +1 more source

Multi‐omics–driven precision medicine

iMeta, Volume 5, Issue 5, October 2026.
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li, Zhe Zhao, Yifan Zhang, Yao Ma, Gaofei Hu, Min Zeng, Zhanqun Yang, Zixuan Zhao, Xin Zhou, Wei Hu, Yuxuan Sun, Meng Su, Jun Li, Matthew Whiteman, Wei Fu, Chao Zhong, Lemin Zheng, Long Chen, Hairong Lv, Rongsheng Zhao, Yi Zhun Zhu   +20 more
wiley   +1 more source

Treatment patterns in homozygous familial hypercholesterolemia: Undertreatment and delayed adoption of low-density lipoprotein receptor-independent therapies. [PDF]

Am J Prev Cardiol
Murdock DJ, Wang L, Gu J, Sanchez RJ, Godin R, Brandt EJ.   +5 more
europepmc   +1 more source

Intraprocedural Hemodynamics During Concomitant Rheocarna Therapy and Maintenance Hemodialysis: Effects of Dialyzer Membrane Type and Circuit Sequence

Journal of Clinical Apheresis, Volume 41, Issue 5, October 2026.
ABSTRACT Chronic limb‐threatening ischemia (CLTI), a severe manifestation of peripheral artery disease, is particularly prevalent among patients receiving maintenance hemodialysis (HD) and is associated with poor limb and survival outcomes. Low‐density lipoprotein (LDL) apheresis, including Rheocarna, is used as adjunctive therapy for refractory CLTI ...
Yusuke Ishizuka, Genshin Sato, Shizuka Ishigaki, Ryo Enoki, Kako Kajiwara, Akihiko Nakasato, Sosuke Kinomura, Saori Kin, Yuji Noguchi, Daisuke Yoshizawa, Koichi Kikuchi, Michiaki Abe, Koki Kumagai, Tetsuhiro Tanaka, Koji Okamoto   +14 more
wiley   +1 more source

Genetic Cascade Screening for Familial Hypercholesterolemia: A Randomized Clinical Trial.

JAMA Netw Open
Nanchen D, Chaouch A, Scuderi R, Faivre V, von Känel T, Ehret G, Brun N, Sudano I, Rickli H, Girod G, Dettwiler AB, Krasieva K, Podmore C, Rodondi N, Moutzouri E, Ballhausen D, Del Giorno R, von Eckardstein A, Beer JH, Gallino A.   +19 more
europepmc   +1 more source

Integrated Clinical, Molecular, and Machine Learning Assessment of Familial Hypercholesterolemia. [PDF]

Life (Basel)
Alay MT, Deniz A, Saat H, Erdem HB.
europepmc   +1 more source

The effects of royal jelly on human health: A narrative review of clinical studies

JSFA reports, Volume 6, Issue 10, Page 422-429, October 2026.
Abstract Royal jelly (RJ) is a natural bioactive substance with documented effects on human health. This narrative review synthesizes evidence from clinical and clinically relevant experimental studies evaluating the therapeutic potential of RJ.
Georgios Goras, Andreas Thrasyvoulou, Evanthia Tsilimpokou   +2 more
wiley   +1 more source

Chronic, Environmentally Relevant PM2.5 Exposure Exacerbates Metabolic Dysfunction‐Associated Steatotic Liver Disease and Early‐Stage Renal Dysfunction in a Rodent Model

The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 10, October 2026.
ABSTRACT While epidemiological studies link fine particulate matter (PM2.5) exposure to metabolic dysfunction‐associated steatotic liver disease (MASLD) and renal dysfunction, a translational gap exists, as most animal models utilize acute, high‐dose exposures that poorly reflect chronic, moderate‐level human scenarios.
Yi‐Siao Chen, Hugo You‐Hsien Lin, Chien‐Tzu Lin, Si‐Hua Huang, Ming‐Lun Yeh, Ming‐Lung Yu, Jin‐Ching Lee, Yao‐Chi Chung, Wei‐Ming Li, Ching‐Chia Li, Shiu‐Feng Huang, Chia‐Hung Yen   +11 more
wiley   +1 more source

Genetic Spectrum of Familial Hypercholesterolemia in Russian North-West Registry: Focus on Correlation Between Clinical and Genetic Diagnosis. [PDF]

J Cardiovasc Dev Dis
Krivosheina MI, Bakaleiko VV, Reutova OV, Sokolnikova PS, Kostareva AA, Alieva AS.   +5 more
europepmc   +1 more source

Familial Hypercholesterolemia: Still an Enigma. [PDF]

JACC Case Rep
Arora S, Kharsa A, Sharma G.
europepmc   +1 more source