Results 221 to 230 of about 340,370 (339)

Positive and Negative Cardiovascular Effects of JAK Inhibitors in Inflammation

ACR Open Rheumatology, Volume 8, Issue 6, June 2026.
Chronic inflammation, characteristic of many autoimmune diseases, such as rheumatoid arthritis (RA), or myeloproliferative neoplasms (MPNs), is an independent driver of accelerated cardiovascular (CV) risk, primarily through proinflammatory cytokines that induce atherosclerosis and endothelial dysfunction.
Aliki Zavoriti, Pierre Miossec
wiley   +1 more source

Differential associations of plasma biomarkers with Alzheimer's disease and small vessel disease: A multimodal imaging study

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract INTRODUCTION We investigated how plasma biomarkers (phosphorylated tau 217 [ptau217], glial fibrillary acidic protein [GFAP], neurofilament light chain [NfL]) relate to imaging markers of small vessel disease (SVD) and Alzheimer's disease (AD), and cognition in memory clinic patients.
Anna Dewenter, Katharina Bürger, Daniel Janowitz, Melina Paulus, Brigitte Nuscher, Fabian Hirsch, Benno Gesierich, Anna Steward, Lukas Frontzkowski, Sebastian N. Roemer‐Cassiano, Zeyu Zhu, Davina Biel, Madleen Klonowski, Gloria Biechele, Sophia Stoecklein, Michael Ewers, Marco Duering, Steffen Tiedt, Matthias Brendel, Nicolai Franzmeier, for the Alzheimer's Disease Neuroimaging Initiative (ADNI)   +20 more
wiley   +1 more source

Integrated Clinical, Molecular, and Machine Learning Assessment of Familial Hypercholesterolemia. [PDF]

Life (Basel)
Alay MT, Deniz A, Saat H, Erdem HB.
europepmc   +1 more source

APOE ε4 and amyloid status moderate the associations between sleep, physical activity, and tau‐PET burden in cognitively unimpaired older adults

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract INTRODUCTION Disturbed sleep and physical inactivity are associated with increased risk for dementia. However, associations with Alzheimer's disease (AD) pathology, and whether these associations differ depending on underlying disease risk, remain unclear. METHODS We examined associations of actigraphy‐derived total volume of physical activity
Daniel D. Callow, Nisha Rani, J. Carson Smith, Anja Soldan, Corinne Pettigrew, Adam P. Spira, Marilyn Albert, Arnold Bakker, BIOCARD Research Team   +8 more
wiley   +1 more source

PCSK9 Inhibitors Reduce Oxidative Stress Biomarkers in Heterozygous Familial Hypercholesterolemia. [PDF]

J Cell Mol Med
Woźniak-Szczepocka A, Pawlos A, Gorzelak-Pabiś P, Broncel M, Bukowska B, Woźniak E.   +5 more
europepmc   +1 more source

Plasma p‐tau markers, vascular factors, and cognitive decline in the CIMA‐Q cohort

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract INTRODUCTION We evaluated associations between phosphorylated au 217 (p‐tau217), p‐tau181, p‐tau231, and vascular risk factors with cognitive outcomes across the Alzheimer's disease (AD) continuum. METHODS Baseline plasma p‐tau concentrations and vascular risk factors were assessed in 277 Consortium for the Early Identification of Alzheimer's ...
Rosalie J. Cottez, Clémence Peyrot, Hélèna L. Denis, Cyntia Tremblay, Andréanne Loiselle, Caroline Dallaire‐Théroux, Ali Filali‐Mouhim, Sébastien S. Hébert, Nicole Leclerc, Kaj Blennow, Henrik Zetterberg, Consortium for the Early Identification of Alzheimer's Disease – Quebec (CIMA‐Q), Marie‐Jeanne Kergoat, Frédéric Calon, Alexa Pichet Binette   +14 more
wiley   +1 more source

A Genome-First Study of Familial Hypercholesterolemia Comparing African and European Ancestry Individuals. [PDF]

Circulation
Winters AH, Kelly MA, Syed MG, Bergquist T, Berry ASF, Mohammed N, Cawley D, Jones LK, Pejaver V, Gidding SS, Oetjens MT.   +10 more
europepmc   +1 more source

Method Comparison of Dried Blood Spot and Plasma Apolipoprotein B Measurement on a Semi‐Automated Analyser: Toward Accessible Lipid Profiling in Resource‐Limited Settings

Analytical Science Advances, Volume 7, Issue 1, June 2026.
ABSTRACT Apolipoprotein B (ApoB) is a key marker of atherogenic lipoprotein burden, but conventional plasma‐based testing requires venous sampling and centralized laboratory infrastructure. Dried blood spot (DBS) sampling offers a minimally invasive alternative suitable for decentralized settings.
Bronwyn Pitampersad, Savathree Madurai, Bhavani Manivannan, Kayla Pillay, Sharana Mahomed   +4 more
wiley   +1 more source

Aortic Stenosis in Homozygous Familial Hypercholesterolemia: The Canadian HoFH Registry. [PDF]

JACC Adv
Erzingatzian A, Al-Baldawi Z, Ruel I, Brown L, Sherman MH, Laflamme N, Bergeron J, Couture P, Paquette M, Baass A, Brisson D, Larouche M, Gaudet D, Cermakova L, Wan D, Brunham LR, Francis GA, Mancini GBJ, Kennedy BA, Hegele RA, Lewis GF, McCrindle BW, Ransom T, McPherson R, Piazza N, de Varennes B, Genest J, Iatan I.   +27 more
europepmc   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1787-1808, June 2026.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source