Results 191 to 200 of about 234,426 (253)

Primary Percutaneous Coronary Intervention Guided by High‐Definition Intravascular Ultrasound (The SPECTRUM Study)

Catheterization and Cardiovascular Interventions, Volume 108, Issue 4, Page 1734-1742, October 1, 2026.
ABSTRACT Background Limited data are available on the use of intravascular ultrasound (IVUS) in patients presenting with ST‐segment elevation myocardial infarction (STEMI). Aims This study aimed to assess the impact of IVUS‐guided primary percutaneous coronary intervention (PCI).
Frederik T. W. Groenland, Annemieke C. Ziedses des Plantes, Tara Neleman, Jurgen M. R. Ligthart, Karen T. Witberg, Rutger‐Jan Nuis, Jeroen M. Wilschut, Roberto Diletti, Wijnand K. den Dekker, Isabella Kardys, Paul Cummins, Karim D. Mahmoud, Nicolas M. Van Mieghem, Joost Daemen   +13 more
wiley   +1 more source

From Phenotype to Genotype and Beyond: Insights into Familial Hypercholesterolemia and Familial Hypertriglyceridemia. [PDF]

Medicina (Kaunas)
Cozma D, Lighezan DF, Tudoran C, Voinescu OR, Mornos C.   +4 more
europepmc   +1 more source

Cholestatic Liver Failure and Hypoglycemia in a Newborn: A Mitochondrial Pathology due to Citrin Deficiency

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT In an infant with cholestasis and recurrent hypoglycemia, the combination of hypercitrullinemia, hypermethioninemia, and hyperthreoninemia should prompt testing for citrin deficiency, because early metabolic and genetic diagnosis allows targeted nutritional treatment and rapid clinical improvement.
Julien Neveu, Mathilde Butori, Anne Spraul, Charlotte Hinault‐Boyer, Mourad Naïmi   +4 more
wiley   +1 more source

Positive Predictive Values of Familial Hypercholesterolemia Diagnoses in the Danish National Patient Registry and the Danish Familial Hypercholesterolemia Registry - A Validation Study. [PDF]

Clin Epidemiol
Knold J, Bork C, Snoer M, Heitmann M, Bang LE, Kanstrup H, Hansen KL, Hedegaard BS, Thomsen KK, Lauridsen BK, Bovin A, Lundquist AA, Al Tamimi HKS, Brorholt-Petersen JU, Christensen TE, Bertelsen MLN, Gohr T, Ellermann A, Hansen CP, Weis A, Nielsen PR, Schmidt EB, Bundgaard H, Henriksen FL, Danish Familial Hypercholesterolemia Study Group.   +24 more
europepmc   +1 more source

From Genomics to Precision Cardiology: A Comprehensive Review of Clinical Applications and Challenges in Cardiovascular Diseases

Clinical Cardiology, Volume 49, Issue 10, October 2026.
Genomic medicine in cardiovascular care is progressing from established diagnostic applications toward integrated risk prediction, multiomics, and emerging therapeutic strategies. ABSTRACT Background Genomic cardiology is an emerging field integrating genetic, molecular, imaging, and digital health data to improve cardiovascular disease (CVD ...
Neda Mohsen‐Pour, Shiva Esmaeili, Aydin Feyzi, Ali Sharafi, Majid Maleki, Samira Kalayinia   +5 more
wiley   +1 more source

Effects of evolocumab on plasma coenzyme Q10 in patients with heterozygous familial hypercholesterolemia. [PDF]

Atheroscler Plus
Tada H, Takeji Y, Takamura M.
europepmc   +1 more source

Phase 1 dose escalation and expansion trial of the bispecific CD47 inhibitor and CD40 agonist Fc‐fusion protein SL‐172154 (SIRPα‐Fc‐CD40L) in patients with higher‐risk myelodysplastic syndrome or acute myeloid leukemia

Cancer, Volume 132, Issue 19, 1 October 2026.
Abstract Background This clinical trial sought to determine whether SL‐172154 could be combined safely and improve the efficacy of azacitidine (AZA) in patients with higher‐risk myelodysplastic syndrome (HR‐MDS) or acute myeloid leukemia (AML). Methods Dose escalation: doses of 1, 3, and 6 mg/kg SL‐172154 was evaluated as monotherapy or in combination ...
Naval G. Daver, Amer M. Zeidan, Anthony S. Stein, Joshua F. Zeidner, Keri Maher, Emily Curran, Dale Bixby, Wanxing Chai‐Ho, Maximilian Stahl, Karen W. L. Yee, Don Stevens, Sawa Ito, Jana Reynolds, Patrick Medd, Emma Searle, Andrew Sochacki, Mary Lynn Savoie, Steven Green, Kazunobu Kato, Robert Hernandez, Simon Metenou, Bo Ma, Lini Pandite, Taylor H. Schreiber, David A. Sallman   +24 more
wiley   +1 more source