Results 191 to 200 of about 224,441 (293)

Cerebral oxygen extraction fraction as a physiological biomarker in vascular cognitive impairment: A study in older adults enriched for small vessel diseases

Alzheimer's &Dementia, Volume 22, Issue 9, September 2026.
Abstract INTRODUCTION Vascular cognitive impairment and dementia (VCID) is a common cause of cognitive impairment, yet validated biomarkers, particularly those reflecting vascular function, remain lacking. Oxygen extraction fraction (OEF), which reflects the functional status of cerebral small vessels, is a potential physiological biomarker for VCID ...
Jie Song, Wen Shi, Julia Suconic, Kaisha Hazel, George Pottanat, Ebony Jones, Tyler Deane, Archana Sharma, Cuimei Xu, Kumiko Oishi, Yifan Gou, Zhiyi Hu, Xin Li, Paul Rosenberg, Rita Kalyani, Abhay Moghekar, Sevil Yasar, Doris Lin, Marilyn Albert, Hanzhang Lu, Dengrong Jiang   +20 more
wiley   +1 more source

From Phenotype to Genotype and Beyond: Insights into Familial Hypercholesterolemia and Familial Hypertriglyceridemia. [PDF]

Medicina (Kaunas)
Cozma D, Lighezan DF, Tudoran C, Voinescu OR, Mornos C.   +4 more
europepmc   +1 more source

Diabetes and the Metabolic Syndrome as Drivers of Neurodegeneration: Convergent Mechanisms Linking Peripheral Neuropathy and Dementia

Annals of Neurology, Volume 100, Issue 3, Page 458-476, September 2026.
The metabolic syndrome, a state of progressive metabolic dysfunction, injures the peripheral and central nervous systems, promoting peripheral neuropathy (PN) and cognitive impairment (CI), respectively. We posit PN and CI are connected in the metabolic syndrome framework, built on the premise that neurons, whether in the peripheral or central nervous ...
Masha G. Savelieff, David L. Bennett, Troels S. Jensen, Eva L. Feldman   +3 more
wiley   +1 more source

Advanced therapy in familial hypercholesterolemia. [PDF]

Can Fam Physician
Gao E, Brunham LR, Goldman RD.
europepmc   +1 more source

Finding Familial Hypercholesterolemia

Clinical Chemistry, 2020
openaire   +2 more sources

Mechanical Thrombus Aspiration for a Young STEMI Patient With Plaque Erosion: Time for a Stent‐Free Approach?

Catheterization and Cardiovascular Interventions, Volume 108, Issue 3, Page 833-839, September 1, 2026.
ABSTRACT A 34‐year‐old man with no cardiovascular history presented with anterior ST‐elevation myocardial infarction and a large thrombotic occlusion of the mid left anterior descending artery. Following potent antithrombotic therapy and mechanical thrombus aspiration, angiography revealed vessel patency without residual significant stenosis, allowing ...
Domenico Simone Castiello, Francesco Greco, Antonio Curcio, Alberto Polimeni   +3 more
wiley   +1 more source

Effects of evolocumab on plasma coenzyme Q10 in patients with heterozygous familial hypercholesterolemia. [PDF]

Atheroscler Plus
Tada H, Takeji Y, Takamura M.
europepmc   +1 more source

Outcomes of an Interventional Approach in STEMI and NSTEMI All‐Comer Octo and Nonagenarians

Clinical Cardiology, Volume 49, Issue 9, September 2026.
All‐cause mortality of an initial invasive strategy versus optimal medical treatment is assessed in 775 all‐comer consecutive (N)STEMI octo/nonagenarians. Nonagenarians were predominantly women, had lower hemoglobin levels, and eGFR. An invasive strategy treatment demonstrated lower 1 year mortality in octo/nonagenarian (N)STEMI patients, most ...
Charlotte E. P. Siegers, Quinten P. Hoogervorst, Jan van Ramshorst, Sanneke P.M. de Boer, Maurits Dirksen, Victor A. W. M. Umans   +5 more
wiley   +1 more source

Positive Predictive Values of Familial Hypercholesterolemia Diagnoses in the Danish National Patient Registry and the Danish Familial Hypercholesterolemia Registry - A Validation Study. [PDF]

Clin Epidemiol
Knold J, Bork C, Snoer M, Heitmann M, Bang LE, Kanstrup H, Hansen KL, Hedegaard BS, Thomsen KK, Lauridsen BK, Bovin A, Lundquist AA, Al Tamimi HKS, Brorholt-Petersen JU, Christensen TE, Bertelsen MLN, Gohr T, Ellermann A, Hansen CP, Weis A, Nielsen PR, Schmidt EB, Bundgaard H, Henriksen FL, Danish Familial Hypercholesterolemia Study Group.   +24 more
europepmc   +1 more source

Vimseltinib for patients with tenosynovial giant cell tumor: A multicenter, open‐label, phase 2 trial

Cancer, Volume 132, Issue 17, 1 September 2026.
Abstract Background Tenosynovial giant cell tumor (TGCT) is a locally aggressive neoplasm caused by dysregulation of the colony‐stimulating factor 1 (CSF1) gene. Patients report substantial pain, stiffness, and declining physical function; those whose disease is not amenable to surgery require systemic therapy.
Silvia Stacchiotti, Jean‐Yves Blay, Piotr Rutkowski, Hans Gelderblom, Alejandro Falcón, Axel Le Cesne, Jayesh Desai, Emanuela Palmerini, César Serrano, Kristen N. Ganjoo, Gina Z. D’Amato, Christopher W. Ryan, Breelyn A. Wilky, Virginia Ferraresi, Ramy Saleh, Vinod Ravi, Albiruni Abdul Razak, Antonio Casado Herráez, Mahbubl Ahmed, Nicholas M. Bernthal, Michiel van de Sande, Mehdi Brahmi, Bartlomiej Szostakowski, Jasmine Sen, Nicholas A. Zeringo, Brooke Harrow, Supraja Narasimhan, Amanda Saunders, Maitreyi G. Sharma, Matthew L. Sherman, Andrew J. Wagner, William D. Tap   +31 more
wiley   +1 more source