Results 151 to 160 of about 340,370 (339)

Psychological determinants and evidence-based behavior change interventions in adherence to therapy for familial hypercholesterolemia

Purpose of review Patients with familial hypercholesterolemia have an elevated risk of premature atherosclerotic cardiovascular disease. Risks can be minimized through pharmacological and ‘lifestyle’ behavioral (low fat diet, physical activity ...
Hagger, MS, Hagger, Martin S., Hamilton, K, Hamilton, Kyra   +3 more
core   +1 more source

The safe and effective use of tofacitinib and ustekinumab combination therapy in infantile onset inflammatory bowel disease

JPGN Reports, EarlyView.
Abstract Infantile‐onset inflammatory bowel disease (IOIBD) is a rare and severe subset of very‐early‐onset IBD, often associated with immune dysregulation and poor response to conventional therapies. Data regarding the use of Janus kinase inhibitors (JAKI) in this population is limited.
Smridhi Mahajan, Christian Wysocki, Bhaskar Gurram   +2 more
wiley   +1 more source

Criteria for Diagnosis of Familial Hypercholesterolemia: A Comprehensive Analysis of the Different Guidelines, Appraising their Suitability in the Omani Arab Population

Oman Medical Journal, 2014
Subjects with Familial hypercholesterolemia are at increased risk for cardiac events such as premature myocardial infarction and early death from coronary heart disease, especially in patients with severe forms of the disease if left unattended ...
Khalid Al-Rasadi, Khalid Al-Waili, Hilal Ali Al-Sabti, Ali Al-Hinai, Khamis Al-Hashmi, Ibrahim Al-Zakwani, Yajnavalka Banerjee   +6 more
doaj   +1 more source

The genetic basis of familial hypercholesterolemia: inheritance, linkage, and mutations

, 2010
Isabel De Castro-Orós1, Miguel Pocoví2, Fernando Civeira11Lipid Unit and Laboratorio de Investigación Molecular, Hospital Universitario Miguel Servet, Instituto Aragonés de Ciencias de la Salud (I+CS), Zaragoza,
Fernando Civeira, Miguel Pocoví, Isabel De Castro-Orós   +2 more
core  

The effects of royal jelly on human health: A narrative review of clinical studies

JSFA reports, EarlyView.
Abstract Royal jelly (RJ) is a natural bioactive substance with documented effects on human health. This narrative review synthesizes evidence from clinical and clinically relevant experimental studies evaluating the therapeutic potential of RJ.
Georgios Goras, Andreas Thrasyvoulou, Evanthia Tsilimpokou   +2 more
wiley   +1 more source

2024 Polish recommendations for the management of familial hypercholesterolemia in children and adolescents

Familial hypercholesterolemia (FH) is the most common monogenic disease leading to the accelerated development of atherosclerotic cardiovascular disease (ASCVD).
Krzysztof Chlebus, Marta Bandura, Jarosław Peregut-Pogorzelski, Bartosz Wasąg, Maria Miszczak-Knecht, Małgorzata Myśliwiec, Anna Wołoszyn-Durkiewicz, Matylda Hennig, Mieczysław Walczak, Jolanta Sykut-Cegielska, Agnieszka Zmysłowska, Maciej Banach   +11 more
core   +1 more source

Chronic, Environmentally Relevant PM2.5 Exposure Exacerbates Metabolic Dysfunction‐Associated Steatotic Liver Disease and Early‐Stage Renal Dysfunction in a Rodent Model

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT While epidemiological studies link fine particulate matter (PM2.5) exposure to metabolic dysfunction‐associated steatotic liver disease (MASLD) and renal dysfunction, a translational gap exists, as most animal models utilize acute, high‐dose exposures that poorly reflect chronic, moderate‐level human scenarios.
Yi‐Siao Chen, Hugo You‐Hsien Lin, Chien‐Tzu Lin, Si‐Hua Huang, Ming‐Lun Yeh, Ming‐Lung Yu, Jin‐Ching Lee, Yao‐Chi Chung, Wei‐Ming Li, Ching‐Chia Li, Shiu‐Feng Huang, Chia‐Hung Yen   +11 more
wiley   +1 more source

Familial hypercholesterolemia: state-of-the-art

Global Cardiology
Familial hypercholesterolemia (FH) affects about 20 million people worldwide and remains markedly underdiagnosed and undertreated. Contemporary studies estimate the prevalence of heterozygous FH (HeFH) at 1 in 192 to 1 in 310, and the prevalence of ...
Ahmed Kamal Siddiqi, Kumail Mustafa Ali, Rameen Shahid, Shamna Haris, Anandita Kulkarni, Iliyan Mithani, Wilhelm Haverkamp, Muhammad Shahzeb Khan   +7 more
doaj   +1 more source

Clinical Genetic Testing for Familial Hypercholesterolemia: JACC Scientific Expert Panel.

Journal of the American College of Cardiology, 2018
Although awareness of familial hypercholesterolemia (FH) is increasing, this common, potentially fatal, treatable condition remains underdiagnosed. Despite FH being a genetic disorder, genetic testing is rarely used.
A. Sturm, J. Knowles, S. Gidding, Z. Ahmad, C. Ahmed, C. Ballantyne, S. Baum, M. Bourbon, A. Carrié, M. Cuchel, S. D. de Ferranti, J. Defesche, T. Freiberger, R. Hershberger, G. Hovingh, L. Karayan, J. Kastelein, I. Kindt, S. Lane, S. Leigh, M. Linton, P. Mata, W. Neal, B. Nordestgaard, R. Santos, M. Harada‐Shiba, E. Sijbrands, N. Stitziel, S. Yamashita, K. Wilemon, D. Ledbetter, D. Rader   +31 more
semanticscholar   +1 more source

High prevalence of genetic determined familial hypercholesterolemia in premature coronary artery disease

, 2019
Carlo Pirazzi,1 Lina Håkansson,1 Carola Gustafsson,1 Elmir Omerovic,1,2 Olov Wiklund,2 Rosellina Margherita Mancina21Department of Cardiology, Sahlgrenska University Hospital, Gothenburg, Sweden; 2Department of Molecular and Clinical Medicine ...
Wiklund O, Håkansson L, Omerovic E, Gustafsson C, Pirazzi C, Mancina RM   +5 more
core