Results 131 to 140 of about 20,467 (242)

Synergistic Anti‐Obesity Effect of Akkermansia muciniphila AKM Lab‐01 and Garcinia cambogia Extract via Gut Microbiota Remodeling in Diet‐Induced Obese Mice

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
Combined administration of pasteurized Akkermansia muciniphila (AKM Lab‐01) and Garcinia cambogia extract (GCE) alleviates high‐fat‐diet‐induced obesity in mice by reducing adiposity, metabolic disturbances, and adipose inflammation, while remodeling gut microbiota and adipose transcriptome, revealing a gut‐host metabolic axis that underpins the ...
Baojia Huang, Zhipeng Chen, Wenbin Xue, Zilun Pu, Yalin Zhou, Sherlyn Sze Ning Koay, Ping Kong, Yingying Zhao, Lihong Tai, Zhou Lan, Yibo Xian, Amanda Juan Chen   +11 more
wiley   +1 more source

Familial Hypercholesterolemia Presenting With Joint Pain in an Adolescent Girl. [PDF]

Cureus
Potla C, Jeevarathnam D, Janarthanan M.
europepmc   +1 more source

Reconceptualizing Dyslipidemia: Diversity of Lipid Imbalances and Their Clinical Implications; A Narrative Review

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims The traditional definition of dyslipidemia focuses on isolated lipid changes (LDL‐C, HDL‐C, triglycerides) and may not fully capture the biological complexity or clinical variability of lipid imbalances. Recent evidence challenges this narrow view, suggesting that dyslipidemia involves broader disruptions in lipid ...
Ali Mansoursamaei, Amirhossein Yadegar, Fatemeh Mohammadi, Seyed Arsalan Seyedi, Soghra Rabizadeh, Sahar Karimpour Reyhan, Alireza Esteghamati, Manouchehr Nakhjavani   +7 more
wiley   +1 more source

Assessment of Selected Clinical Chemistry Analytes Among Hypertensive Patients at Wallaga University Referral Hospital, Nekemte, Oromia, Western Ethiopia: A Comparative Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Hypertension (HTN) is a long‐term condition marked by consistently high arterial blood pressure. It is a leading contributor to cardiovascular diseases and early mortality around the globe. It increases the risk of ischemic heart disease, stroke, chronic kidney disease (CKD), and dementia.
Amanuel Hika, Sintayehu Asaye Biya, Temam Ibrahim Husen, Negesse Bokona Rufe, Hundesa Emana Urgesa, Bedasa Addisu   +5 more
wiley   +1 more source

Genetic screening and response to drug therapy in familial hypercholesterolemia. [PDF]

Front Mol Biosci
Lu Y, Chen Q, Zhang W, Dong J, Zha L.
europepmc   +1 more source

Atorvastatin Reduces Alcohol‐Related Cardiac and Liver Tissue Damage, Oxidative Stress, Inflammation, Apoptosis, and Thiol‐Disulfide Imbalance in Rats

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Atorvastatin (40 mg/kg) inhibited fibrosis, hypertrophy, apoptosis, inflammation, and oxidative stress caused by alcohol consumption. It may contribute to the regulation of mitochondrial function and thiol/disulfide balance by limiting alcohol‐related heart and liver damage.
Cumaali Demirtas, Şahhan Kılıç, Mert Babaoğlu, Süha Asal, Elif Gökçe Tenekeci, Hakan Beyaztaş, Eray Metin Guler, Salime Pelin Erguven, Kubra Sevgin   +8 more
wiley   +1 more source

Integrated Clinical, Molecular, and Machine Learning Assessment of Familial Hypercholesterolemia. [PDF]

Life (Basel)
Alay MT, Deniz A, Saat H, Erdem HB.
europepmc   +1 more source

Lack of Differences in the Pharmacokinetics of Therapeutic Monoclonal Antibodies Between Japanese and Non‐Japanese Individuals

The Journal of Clinical Pharmacology, Volume 66, Issue 8, August 2026.
Abstract Evaluation of the pharmacokinetics (PK) of new drugs in Japanese individuals is regularly requested by the Japanese regulatory agency prior to participation in global clinical trials or for bridging approaches for regulatory approval. However, the need for PK assessments in the Japanese population may be less compelling for monoclonal ...
Paridhi Gupta, Ashish Sharma, Bernd Meibohm   +2 more
wiley   +1 more source

PCSK9 Inhibitors Reduce Oxidative Stress Biomarkers in Heterozygous Familial Hypercholesterolemia. [PDF]

J Cell Mol Med
Woźniak-Szczepocka A, Pawlos A, Gorzelak-Pabiś P, Broncel M, Bukowska B, Woźniak E.   +5 more
europepmc   +1 more source

Preliminary Validation of a Novel Genetic Knowledge Scale for Familial Hypercholesterolemia: Evaluation of Face Validity and Core Concepts

Journal of Genetic Counseling, Volume 35, Issue 4, August 2026.
ABSTRACT Facilitating patient‐informed decision making is central to the genetic counseling practice. The Multidimensional Model of Informed Choice (MMIC) evaluates informed decisions in genetic testing, but validated MMIC measures for inherited cardiac conditions are lacking.
Emily Moss, Jeffrey Wigle, Claudia Carriles‐Landry, Kim Mitchell, Hannah Wand, Jill Slamon, Roya Mostafavi, Amy Yonda, Susan Christian   +8 more
wiley   +1 more source