Results 111 to 120 of about 234,426 (253)

Hyperlipidaemia in youth with type 1 diabetes: Are current guidelines clinically useful?

Diabetic Medicine, EarlyView.
Abstract Aims Dyslipidaemia in youth with type 1 diabetes mellitus (T1D) is emerging as an important modifiable cardiovascular risk factor. International consensus guidelines to screen this entity have evolved over time. To further evaluate this in an Australian context, we investigated adherence to such guidelines over the course of patient care ...
Farrah Rodrigues, Mary White, Michele A. O'Connell   +2 more
wiley   +1 more source

Rheumatoid-like hand deformities and aortic valve disease in a 13-year-old girl with homozygous familial hypercholesterolemia: a case report

Journal of Medical Case Reports
Background Familial hypercholesterolemia is an autosomal dominant disorder characterized by elevated serum low-density lipoprotein cholesterol levels, tendon xanthomas, and an increased risk of atherosclerotic heart disease.
Anjuman Ara Rahman, Abhijit Datta, Kamal Uddin Ahmed, Anindita Das Barshan, Mohammad Jahid Hasan   +4 more
doaj   +1 more source

Cardiovascular risk estimation and management in Familial Hypercholesterolemia patients

, 2021
Objectives and study samples: - Estimate cardiovascular disease (CVD) risk; - What are the lipid-lowering therapy (LLT) strategies; - How many are reaching LDL-C targets; … in Familial Hypercholesterolemia (FH) patients and in the Portuguese general ...
Chora, J.R., Bourbon, M., Alves, A.C., Medeiros, A.M.   +3 more
core  

Dyslipidaemia, Chronic Kidney Disease and Diabetes Mellitus: A Triple Threat to Cardiovascular Health

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Diabetes mellitus (DM) and chronic kidney disease (CKD) frequently coexist and together create a ‘triple threat’ with dyslipidaemia, enhancing the risk for cardiovascular morbidity and mortality. Diabetic kidney disease (DKD) leads to altered lipid metabolism through insulin resistance, inflammation and oxidative stress resulting in an ...
Ann S. Forrest, Priyanka Majety, Stéphanie B. Mayer, Om P. Ganda   +3 more
wiley   +1 more source

Safety and Effectiveness of Low‐Density Lipoprotein Cholesterol–Lowering Therapy With Evolocumab for Familial Hypercholesterolemia/Hypercholesterolemia in Japan: A Real‐World, Postmarketing, Single‐Arm Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Evolocumab is the first monoclonal antibody against proprotein convertase subtilisin/kexin type 9 approved in Japan for familial hypercholesterolemia (FH) and hypercholesterolemia; however, data on its safety and effectiveness in the real ...
Koutaro Yokote, Junya Ako, Kazuo Kitagawa, Nobuhiro Osada, Feng Sheng, Masae Sonoda, Tamio Teramoto   +6 more
doaj   +1 more source

How well can familial hypercholesterolemia be identified in an electronic health record database?

, 2018
Katherine E Mues,1 Alina N Bogdanov,2 Keri L Monda,1 Larisa Yedigarova,3 Alexander Liede,1 Lee Kallenbach2 1Center for Observational Research, Amgen Inc., Thousand Oaks, CA, USA; 2Practice Fusion, San Francisco, CA, USA; 3US Medical Affairs, Amgen ...
Yedigarova L, Monda KL, Kallenbach L, Mues KE, Liede A, Bogdanov AN   +5 more
core  

CD36‐mediated lipid rewiring in the metabolic adaptation of tumour ecosystems

The FEBS Journal, EarlyView.
Nutrient deprivation drives a lipid‐centric shift in tumour metabolic symbiosis and signalling network. CD36 functions as a bidirectional bridge, transferring fatty acids from stromal donors (adipocytes, CAFs) to the ecosystem tumour‐ and microenvironment‐dependently.
Anna Sebestyén, Viktória Varga, Fatime Szalai, Risa Miyaura, Nóra Förhécz, Bálint Csikós, Rebeka Gelencsér, Zsófia Gábriel, Timea Komlódi, Katalin Dezső, Ildikó Krencz, Dorottya Moldvai   +11 more
wiley   +1 more source

A healthcare cognitive decision support system for doctor–patient co‐decisions in primary care using sentiment analysis

International Transactions in Operational Research, EarlyView.
Abstract Decision support systems (DSS) in the artificial intelligence era require the integration of cognitive and affective information to support human‐centred decision‐making. This study proposes a healthcare cognitive decision support system (HC‐DSS) based on lexicon sentiment analysis for doctor–patient co‐decisions in primary care.
J.M. Moreno‐Jiménez, R. Aznar, C. Moreno‐Loscertales, M. Sancho, A. Sarango, A. Turón, J. Navarro   +6 more
wiley   +1 more source

Tuberous Xanthoma: A Clue to the Diagnosis of Familial Hypercholesterolemia

A 35-year-old patient found to have tuberous xanthomas was diagnosed to have familial hypercholesterolemia (FH).
Anthony Nilesh Ranjeev Fernandopulle, Anne Thushara Matthias   +1 more
core   +1 more source

Impact of functional studies on updating the classification of genetic variants in familial hypercholesterolemia

, 2021
About familial hypercholesterolemia and the impact of functional studies on updating the classification of its genetic variants.N/
Alves, Ana Catarina
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