Results 121 to 130 of about 234,426 (253)

Female genital lichen sclerosus

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This review provides a comprehensive overview of clinical presentation and emerging evidence supporting a predominantly immune‐mediated pathogenesis characterized by Th1‐skewed inflammation, epithelial dysfunction and progressive fibrosis. Contributory factors including the emerging role for occlusive exposure of susceptible epithelium to urine are ...
Ashley Spencer, Sandra Jerkovic Gulin
wiley   +1 more source

Family hypercholesterolemia due to LDLR gene in Vietnamese children: characteristics of phenotype and genotype

Molecular Genetics and Metabolism Reports
Background: Familial hypercholesterolemia (FH) results in elevated LDL cholesterol, contributing to atherosclerosis and early-onset cardiovascular disease.
Mai Thi Thanh Do, Dung Chi Vu, Mai Thi Chi Tran, Thao Phuong Bui, Ngoc Thi Bich Can, Khanh Ngoc Nguyen   +5 more
doaj   +1 more source

Driving Navigation in Older Adults Across the Alzheimer's Disease Continuum

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background and Objectives To examine whether time from amyloid positivity (amyloid time), a continuous measure of biological Alzheimer's disease (AD) progression, is associated with differences in navigation‐related driving behaviors among older adults.
Yiqi Zhu, Julie K. Wisch, Ziqiao Jiao, David C. Brown, Noor Al Hammadi, Tammie L. S. Benzinger, John C. Morris, Beau M. Ances, Ganesh M. Babulal   +8 more
wiley   +1 more source

What is precision public health and where does FH fit in? [PDF]

Presentation at the FH Summit October 21, 2019, theme: familial hypercholesterolemia as a prototype for precision public health.Khoury-FHsummit-2019_508 ...

core  

Vision Impairment, Vision Correction, and Dementia Risk in Mild Cognitive Impairment

Journal of the American Geriatrics Society, EarlyView.
Among individuals with mild cognitive impairment, no vision impairment (VI) and corrected VI were associated with a lower risk of dementia than uncorrected VI, particularly among those aged < 75 years.
Huilin Tang, David A. Wolk, Gui‐shuang Ying, Tiansheng Wang, Steven T. DeKosky, Yong Chen   +5 more
wiley   +1 more source

Associations of Person‐Centred Planning and Service Coordination With Health Outcomes of Adults With Developmental Disabilities

Journal of Intellectual Disability Research, EarlyView.
ABSTRACT Background People with intellectual and developmental disabilities (IDD) experience significant health and healthcare disparities. Home and community‐based services (HCBS) are crucial for the health and well‐being of adults with IDD, and national regulations mandate person‐centred planning (PCP) for all HCBS service administration.
Elad Daniels, Joseph Caldwell, Kaitlin Stober   +2 more
wiley   +1 more source

The genetic basis of familial hypercholesterolemia: inheritance, linkage, and mutations

, 2010
Isabel De Castro-Or&oacute;s1, Miguel Pocov&iacute;2, Fernando Civeira11Lipid Unit and Laboratorio de Investigaci&oacute;n Molecular, Hospital Universitario Miguel Servet, Instituto Aragon&eacute;s de Ciencias de la Salud (I+CS), Zaragoza,
Fernando Civeira, Miguel Pocov&iacute;, Isabel De Castro-Or&oacute;s   +2 more
core  

Psychological determinants and evidence-based behavior change interventions in adherence to therapy for familial hypercholesterolemia

Purpose of review Patients with familial hypercholesterolemia have an elevated risk of premature atherosclerotic cardiovascular disease. Risks can be minimized through pharmacological and ‘lifestyle’ behavioral (low fat diet, physical activity ...
Hagger, MS, Hagger, Martin S., Hamilton, K, Hamilton, Kyra   +3 more
core   +1 more source

Osteoporosis and Periodontitis: Two‐Way Epidemiological and Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
This review investigates the main mechanistic pathways connecting local periodontitis to systemic osteoporosis. Seven interconnected mechanisms are identified. ABSTRACT Osteoporosis and periodontitis are highly prevalent, chronic inflammatory diseases that constitute a major global health burden.
Jia Chang, Geeta Madhuri Bhuvanagiri, Megan Dulkanchainun, Cunyu Wang   +3 more
wiley   +1 more source

The Oral‐Hepatic Axis: Epidemiological and Mechanistic Links Between Periodontal and Liver Diseases

Journal of Periodontal Research, EarlyView.
This review summarizes current epidemiological, clinical and mechanistic evidence linking periodontitis and chronic liver diseases, highlighting the oral‐gut‐liver axis, shared immunometabolic and nutritional pathways and opportunities for integrated preventive and therapeutic strategies.
Sinem Esra Sahingur, Kinga Grzech‐Leśniak, Samuel F. Suslavich, Janina Golob Deeb   +3 more
wiley   +1 more source