Results 101 to 110 of about 224,441 (293)

Clustering of Cerebral Microbleeds in Cerebral Amyloid Angiopathy: A Flow Territory‐Based Analysis

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Cerebral microbleeds (CMBs) are a key imaging marker of cerebral amyloid angiopathy (CAA), but their individual spatial distribution and potential clustering remain poorly understood. Purpose This study assessed whether CMBs exhibit patient‐specific, flow territory‐based clustering in sporadic (sCAA) and Dutch‐type hereditary CAA (D‐
Manon R. Schipper, Reinier G. J. van der Zwet, Jelle J. Goeman, Thijs W. van Harten, Emma A. Koemans, Marieke J. H. Wermer, Marianne A. A. van Walderveen, Matthias J. P. van Osch   +7 more
wiley   +1 more source

Evidence for a third genetic locus causing familial hypercholesterolemia: a non-LDLR, non-APOB kindred1

Journal of Lipid Research, 1999
Monogenically inherited hypercholesterolemia is most commonly caused by mutations at the low density lipoprotein receptor (LDLR) locus causing familial hypercholesterolemia (FH) or at the apolipoprotein B (APOB) locus causing the disorder familial ...
L. Haddad, I.N.M. Day, S. Hunt, R.R. Williams, S.E. Humphries, P.N. Hopkins   +5 more
doaj   +1 more source

Genetically confirmed familial hypercholesterolemia in outpatients with hypercholesterolemia.

Journal of geriatric cardiology : JGC, 2018
Familial hypercholesterolemia (FH) is an autosomal dominant disorder of lipoprotein metabolism which can lead to premature coronary heart disease (pCHD). There are about 3.8 million potential FH patients in China, whereas the clinical and genetic data of FH are limited.Dutch Lipid Clinic Network (DLCN) criteria was used to diagnose FH in outpatients ...
Wang, Xu, Jiang, Long, Sun, Li-Yuan, Wu, Yue, Wen, Wen-Hui, Wang, Xi-Fu, Liu, Wei, Zhou, Yu-Jie, Wang, Lu-Ya   +8 more
openaire   +2 more sources

Treatmen of Familial Hypercholesterolemia

, 2017
Familial Hypercholesterolemia (FH) is a genetic disorder that affect lipoprotein metabolism, which leads to premature CVD , thus its treatment in early ages are highly importanthbkáltalános orvosangolegységes ...
Arkan, Abdollah
core  

Severity of periodontitis and risk of ischemic stroke: A systematic review and meta‐analysis

Journal of Periodontology, EarlyView.
Abstract Background Periodontitis is a prevalent chronic inflammatory disease with a systemic inflammatory burden and is implicated with vascular pathology. This systematic review and meta‐analysis evaluates the association between varying severities of periodontitis and ischemic stroke with various diagnostic criteria.
Steven Sitt, Chloe J. Chang, Chin‐Wei Wang   +2 more
wiley   +1 more source

The safe and effective use of tofacitinib and ustekinumab combination therapy in infantile onset inflammatory bowel disease

JPGN Reports, EarlyView.
Abstract Infantile‐onset inflammatory bowel disease (IOIBD) is a rare and severe subset of very‐early‐onset IBD, often associated with immune dysregulation and poor response to conventional therapies. Data regarding the use of Janus kinase inhibitors (JAKI) in this population is limited.
Smridhi Mahajan, Christian Wysocki, Bhaskar Gurram   +2 more
wiley   +1 more source

The effects of royal jelly on human health: A narrative review of clinical studies

JSFA reports, EarlyView.
Abstract Royal jelly (RJ) is a natural bioactive substance with documented effects on human health. This narrative review synthesizes evidence from clinical and clinically relevant experimental studies evaluating the therapeutic potential of RJ.
Georgios Goras, Andreas Thrasyvoulou, Evanthia Tsilimpokou   +2 more
wiley   +1 more source

Criteria for Diagnosis of Familial Hypercholesterolemia: A Comprehensive Analysis of the Different Guidelines, Appraising their Suitability in the Omani Arab Population

Oman Medical Journal, 2014
Subjects with Familial hypercholesterolemia are at increased risk for cardiac events such as premature myocardial infarction and early death from coronary heart disease, especially in patients with severe forms of the disease if left unattended ...
Khalid Al-Rasadi, Khalid Al-Waili, Hilal Ali Al-Sabti, Ali Al-Hinai, Khamis Al-Hashmi, Ibrahim Al-Zakwani, Yajnavalka Banerjee   +6 more
doaj   +1 more source

The genetic basis of familial hypercholesterolemia: inheritance, linkage, and mutations

, 2010
Isabel De Castro-Orós1, Miguel Pocoví2, Fernando Civeira11Lipid Unit and Laboratorio de Investigación Molecular, Hospital Universitario Miguel Servet, Instituto Aragonés de Ciencias de la Salud (I+CS), Zaragoza,
Fernando Civeira, Miguel Pocoví, Isabel De Castro-Orós   +2 more
core  

Anti‐hypercholesterolemic effects of barley and its role in the management of metabolic disorders: A comprehensive review

JSFA reports, EarlyView.
Abstract The dietary and lifestyle practices have predominantly compromised human health, which are influenced by modernization and industrialization. Hypercholesterolemia, caused by the consumption of fatty and fried foods and a sedentary lifestyle, is a major modifiable risk factor for cardiovascular disease and commonly coexists with obesity ...
Muhammad Usman Khalid, Muhammad Tauseef Sultan, Sagun Kharel, Umrah Zafar, Naima Tariq, Muhammad Maaz, Mutjardah Zarrish, Nuzhat Shamim, Bipindra Pandey   +8 more
wiley   +1 more source