Results 91 to 100 of about 234,426 (253)
Functional genomics of Familial Hypercholesterolemia
, 2016 Main aim of the Portuguese Family Hypercholesterolemia study: to identify the cause of the dyslipidaemia in patients with a clinical phenotype of Familial Hypercholesterolaemia (FH)
Alves, Ana Catarina
core
Familial hypercholesterolemia (FH) is the most common monogenic disease leading to the accelerated development of atherosclerotic cardiovascular disease (ASCVD).
Krzysztof Chlebus +11 more
core +1 more source
Lipids, EarlyView.ABSTRACT Studies have shown that omega‐3 fatty acids may protect against cardiovascular diseases (CVDs) and related metabolic conditions. UK Biobank is a large cohort study that includes data on plasma omega‐3 fatty acids at study entry and health outcomes during the follow‐up period.
Warda Tul Firdous, Philip C. Calder
wiley +1 more source
, 2019 Carlo Pirazzi,1 Lina Håkansson,1 Carola Gustafsson,1 Elmir Omerovic,1,2 Olov Wiklund,2 Rosellina Margherita Mancina21Department of Cardiology, Sahlgrenska University Hospital, Gothenburg, Sweden; 2Department of Molecular and Clinical Medicine ...
Wiklund O +5 more
core
Neuroprotection, EarlyView.Abstract Prime editing, a novel clustered regularly interspaced short palindromic repeats (CRISPR)‐based technology, fuses a reverse transcriptase (RT) to an engineered CRISPR‐associated protein 9 (Cas9) and uses a prime editing guide RNA (pegRNA)‐encoded template.
Tianshan Ji +4 more
wiley +1 more source
Familial hypercholesterolemia: state-of-the-art
Global CardiologyFamilial hypercholesterolemia (FH) affects about 20 million people worldwide and remains markedly underdiagnosed and undertreated. Contemporary studies estimate the prevalence of heterozygous FH (HeFH) at 1 in 192 to 1 in 310, and the prevalence of ...
Ahmed Kamal Siddiqi +7 more
doaj +1 more source
Herbal Therapeutics in Osteoporosis: Mechanisms, Evidence, and Translational Potential
Phytotherapy Research, EarlyView.Schematic overview of bone remodeling dysregulation in osteoporosis and the multi‐target protective role of herbal therapeutics. ABSTRACT Osteoporosis is a chronic bone disease marked by reduced density and increased fracture risk. Current treatments face limitations in safety, efficacy, and long‐term adherence, prompting interest in alternative ...
Elnaz Vafadar Moradi +5 more
wiley +1 more source
A case report of giant tuberous xanthoma with type IIa familial hypercholesterolemia
Indian Journal of Paediatric DermatologyTuberous xanthomas are nontender, yellow to red papules to nodules that occur on the extensor surface, and trauma-prone areas such as the elbows, knees, Achilles tendon, and buttocks.
Bommakanti Sai Sharanya +3 more
doaj +1 more source
Prediction of 10‐Year Incident Hypertension After Pregnancy: A Population‐Based Cohort Study
BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.ABSTRACT Objective To develop a model including pregnancy‐related factors for the prediction of incident hypertension after pregnancy and to assess the impact of pregnancy‐related factors on model performance. Design Population‐based cohort study. Setting Routine primary care data linked to the data from the Dutch Perinatal Registry and Statistics ...
Zhixun Yang +7 more
wiley +1 more source