Results 141 to 150 of about 224,441 (293)

Cost-effectiveness analysis of the genetic screening program for familial hypercholesterolemia in The Netherlands.

, 2004
Familial hypercholesterolemia (FH) is associated with pronounced atherosclerosis leading to premature cardiovascular disease and untimely death. Despite the availability of effective preventative drug treatments, many affected individuals remain ...
Umans-Eckenhausen, Marina A. W., David Wonderling, Margaret Thorogood, Wonderling, David, Kastelein, John JP, Thorogood, Margaret, Marina Umans-Eckenhausen, Defesche, Joep C., Joep Defesche, Umans-Eckenhausen, Marina AW, Defesche, Joep C, Marks, Dalya, John Kastelein, Kastelein, John J. P., Dalya Marks   +14 more
core   +1 more source

Dyslipidaemia, Chronic Kidney Disease and Diabetes Mellitus: A Triple Threat to Cardiovascular Health

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Diabetes mellitus (DM) and chronic kidney disease (CKD) frequently coexist and together create a ‘triple threat’ with dyslipidaemia, enhancing the risk for cardiovascular morbidity and mortality. Diabetic kidney disease (DKD) leads to altered lipid metabolism through insulin resistance, inflammation and oxidative stress resulting in an ...
Ann S. Forrest, Priyanka Majety, Stéphanie B. Mayer, Om P. Ganda   +3 more
wiley   +1 more source

Family hypercholesterolemia due to LDLR gene in Vietnamese children: characteristics of phenotype and genotype

Molecular Genetics and Metabolism Reports
Background: Familial hypercholesterolemia (FH) results in elevated LDL cholesterol, contributing to atherosclerosis and early-onset cardiovascular disease.
Mai Thi Thanh Do, Dung Chi Vu, Mai Thi Chi Tran, Thao Phuong Bui, Ngoc Thi Bich Can, Khanh Ngoc Nguyen   +5 more
doaj   +1 more source

Genes Potentially Associated with Familial Hypercholesterolemia

, 2019
This review addresses the contribution of some genes to the phenotype of familial hypercholesterolemia. At present, it is known that the pathogenesis of this disease involves not only a pathological variant of low-density lipoprotein receptor and its ...
Svetlana Mikhailova, Dinara Ivanoshchuk, Elena Shakhtshneider, Olga Timoshchenko   +3 more
core   +1 more source

CD36‐mediated lipid rewiring in the metabolic adaptation of tumour ecosystems

The FEBS Journal, EarlyView.
Nutrient deprivation drives a lipid‐centric shift in tumour metabolic symbiosis and signalling network. CD36 functions as a bidirectional bridge, transferring fatty acids from stromal donors (adipocytes, CAFs) to the ecosystem tumour‐ and microenvironment‐dependently.
Anna Sebestyén, Viktória Varga, Fatime Szalai, Risa Miyaura, Nóra Förhécz, Bálint Csikós, Rebeka Gelencsér, Zsófia Gábriel, Timea Komlódi, Katalin Dezső, Ildikó Krencz, Dorottya Moldvai   +11 more
wiley   +1 more source

Knowledge, attitude, and practice of physicians towards familial hypercholesterolemia in north regions of Saudi Arabia

Journal of the Pakistan Medical Association
Objectives: To assess knowledge, attitude and practice of physicians regarding familial hypercholesterolemia. Method: The cross-sectional study was conducted from October to December 2022 in Aljouf, Tabouk, Hail and northern border regions of Saudi ...
Aseel Awad Alsaidan
doaj   +1 more source

Driving Navigation in Older Adults Across the Alzheimer's Disease Continuum

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background and Objectives To examine whether time from amyloid positivity (amyloid time), a continuous measure of biological Alzheimer's disease (AD) progression, is associated with differences in navigation‐related driving behaviors among older adults.
Yiqi Zhu, Julie K. Wisch, Ziqiao Jiao, David C. Brown, Noor Al Hammadi, Tammie L. S. Benzinger, John C. Morris, Beau M. Ances, Ganesh M. Babulal   +8 more
wiley   +1 more source

Familial Hypercholesterolemia

Journal of Atherosclerosis and Thrombosis, 2014
Tamio, Teramoto, Jun, Sasaki, Shun, Ishibashi, Sadatoshi, Birou, Hiroyuki, Daida, Seitaro, Dohi, Genshi, Egusa, Takafumi, Hiro, Kazuhiko, Hirobe, Mami, Iida, Shinji, Kihara, Makoto, Kinoshita, Chizuko, Maruyama, Takao, Ohta, Tomonori, Okamura, Shizuya, Yamashita, Masayuki, Yokode, Koutaro, Yokote, Mariko, Harada-Shiba, Hidenori, Arai, Hideaki, Bujo, Atsushi, Nohara, Takao, Ohta, Shinichi, Oikawa, Tomoo, Okada, Akihiko, Wakatsuki   +25 more
openaire   +3 more sources

Associations of Person‐Centred Planning and Service Coordination With Health Outcomes of Adults With Developmental Disabilities

Journal of Intellectual Disability Research, EarlyView.
ABSTRACT Background People with intellectual and developmental disabilities (IDD) experience significant health and healthcare disparities. Home and community‐based services (HCBS) are crucial for the health and well‐being of adults with IDD, and national regulations mandate person‐centred planning (PCP) for all HCBS service administration.
Elad Daniels, Joseph Caldwell, Kaitlin Stober   +2 more
wiley   +1 more source

Hypocholesterolemia in liver and cardiovascular disease: Friend or foe?

Journal of Internal Medicine, EarlyView.
Abstract Hypocholesterolemia is perceived as benign given its association with lower cardiovascular risk. However, genetic and epidemiological evidence indicates that persistently low levels of low‐density lipoprotein cholesterol (LDL‐C) and apolipoprotein B (ApoB) arise from distinct biological mechanisms with different hepatic implications ...
Valentina Flagiello, Emelie Barreby, Umberto Vespasiani‐Gentilucci, Stefano Romeo   +3 more
wiley   +1 more source