Results 141 to 150 of about 53,176 (324)

COVID-19 on a Patient with Familial Hypercholesterolemia

, 2020

openalex   +1 more source

Development and analytical validation of a targeted short‐read next generation sequencing‐based pharmacogenetic panel for comprehensive variant detection

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Genomic profiling of patients for genetic variants that modify the effect of specific medications has many benefits, including the possibility of avoiding toxicities and ensuring an adequate effect of the medication. Our intention was to develop a comprehensive, high‐quality pharmacogenetic test panel for clinical use ...
Anna Gréen, Nils Johan Fredriksson, Michael Andresen, Jon Jonasson, Malin Lindqvist Appell, Henrik Gréen   +5 more
wiley   +1 more source

Malaltia Ateroscleròtica Coronària silent en pacients amb Hipercolesterolèmia Familiar Heterozigota [PDF]

, 2012
L'Hipercolesterolèmia Familiar Heterozigota (HFHe) és una malaltia monogènica que predisposa a una major morbimortalitat cardiovascular. Aquest estudi prospectiu de casos i controls pretén avaluar la prevalença de Malaltia Arteroscleròtica Coronaria (MAC)
Universitat Autònoma de Barcelona. Departament de Medicina, Universitat Autònoma de Barcelona. Facultat de Medicina, Viladés Medel, David   +2 more
core  

Coronary and aortic atherosclerosis in WHHL rabbits, an animal model of familial hypercholesterolemia

, 1994
Masahiro Shiomi, Takuo Ito, Tatsuro Yata
openalex   +1 more source

Is Liver Transplant Curative in Homozygous Familial Hypercholesterolemia? A Review of Nine Global Cases [PDF]

, 2022
Mohammed Al Dubayee, Meral Kayıkçıoğlu, Jeanine E. Roeters van Lennep, Nadia Hergli, Pedro Mata   +4 more
openalex   +1 more source

Cardiometabolic Risk in First Degree Relatives of Women With Polycystic Ovary Syndrome (PCOS)

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Polycystic ovary syndrome (PCOS) is a common multisystem disorder with reproductive, cardiometabolic and psychological implications. Genetic factors play a role in the pathogenesis of PCOS. We sought to investigate the cardiometabolic health of first degree relatives (FDR) of women with PCOS.
Su Jen Chua, Xinyi Wu, Tahani Al Kindi, Bulent O. Yildiz, Aya Mousa, Loyal Pattuwage, Helena Teede, Anju E. Joham, Chau Thien Tay   +8 more
wiley   +1 more source

Constitutional and environmental factors related to serum lipid and lipoprotein levels [PDF]

Serum lipoproteins and lipids in 657 human males correlated to multiple constitutional and environmental ...
Graybiel, A., Harlan, W. R., Jr., Mitchell, R. E., Oberman, A., Wherry, R. J., Jr.   +4 more
core   +1 more source

Familial Hypercholesterolemia [PDF]

Circulation, 2020
openaire   +2 more sources

Older Adults' Self‐Care and Family Caregiver Contribution in Multiple Chronic Conditions: A Dyadic Qualitative Study

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aims To explore how older adult‐family caregiver dyads jointly manage multiple chronic conditions. Specifically, it investigates how dyads (i) prioritise chronic diseases, (ii) make and negotiate decisions related to self‐care and (iii) define and distribute self‐care tasks and caregiver contributions.
Giulia Andrea Baldan, Irene Dello Iacono, Valentina Giurissevich, Davide Ausili, Ercole Vellone, Maddalena De Maria, Maria Matarese   +6 more
wiley   +1 more source

Family hypercholesterolemia due to LDLR gene in Vietnamese children: characteristics of phenotype and genotype

Molecular Genetics and Metabolism Reports
Background: Familial hypercholesterolemia (FH) results in elevated LDL cholesterol, contributing to atherosclerosis and early-onset cardiovascular disease.
Mai Thi Thanh Do, Dung Chi Vu, Mai Thi Chi Tran, Thao Phuong Bui, Ngoc Thi Bich Can, Khanh Ngoc Nguyen   +5 more
doaj   +1 more source