Results 141 to 150 of about 2,573,215 (300)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

A conciliação de papéis profissionais e familiares: o mecanismo psicológico de spillover

open access: yesPsicologia: Teoria e Pesquisa
A maioria dos estudos sobre o tema da conciliação entre a vida profissional e familiar tem assumido uma perspectiva negativa e de conflito, focando as dificuldades nesta conciliação.
Marisa Matias, Anne Marie Fontaine
doaj   +1 more source

Analisis Pengaruh Work Family Conflict dan Role Stress terhadap Komitmen Organisasional Karyawan [PDF]

open access: yes, 2016
Jumlah villa di Bali yang semakin berkembang, menuntut The Clubs Villas memiliki keunggulan kompetitif dalam bersaing dengan memperhatikan karyawan, melalui kejadian masalah-masalah dalam pengelolaan sumber daya manusia khususnya dalam membina komitmen ...
Sudibya, G. A. (Gede)   +1 more
core   +1 more source

ANALISIS STRESOR KERJA, DUKUNGAN ORGANISASIONAL PERSEPSIAN, DAN JENDER TERHADAP WORK-FAMILY CONFLICT DAN FAMILY-WORK CONFLICT

open access: yesJurnal Ekonomi dan Bisnis, 2010
The current study examined the impact of perceived organizational support (POS), workstressor, and gender on work-family conflict (WFC) and family-work conflict (FWC) variables.The participants were 100 lecturers working full-time for a variety of universities in Semarang.T-test and hierarchical regression analysis were used to test the hypotheses. The
openaire   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Job, Family and Individual Factors as Predictors of Work-Family Conflict [PDF]

open access: yes, 2008
The growing interest in understanding fully the interface of work and family roles and their antecedents has stimulated the development of a predictive model of work-family conflict.
Ahmad, Aminah
core  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Analisis Work Family Conflict, Stres Kerja Dan Kinerja Wanita Berperan Ganda Pada Yayasan Compassion East Indonesia [PDF]

open access: yes, 2015
The research was conducted with the objective of verifying the influence of Work Family Conflict consists of work to family conflict and family to work conflict and with job stress to analyze performance of dual role women in the foundation Compassion ...
Roboth, J. Y. (Jane)
core   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

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