Results 141 to 150 of about 1,077,598 (298)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Effects of Work–Family Conflict and Facilitation Profiles on Work Engagement
SocietiesAchieving the balance between work and family life needs a holistic viewpoint on how these two aspects interact. It poses a significant challenge due to its impact on individuals, organizations, and society.
Carla Carvalho +4 more
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Crisis Coming Home? Firm Performance During the Economic Crisis and Managers‘ Work-Family Conflict [PDF]
, 2015 The economic crisis over the past years has challenged managers in many ways. In our longitudinal study during the global recession, we examine how perceived firm performance interacts with sources of supervisor support and stress to affect managers ...
Sieger, Philipp +2 more
core
Mitigating Family-work Conflict and Cognitive Absenteeism for Sustainable Work Environments
International Research Journal of Multidisciplinary ScopeFamily problems slow down a person’s ability to concentrate at work. This problem is commonly seen among working women. Therefore, this study focuses on working. The PERMA model of well-being is used as a mediator to explain how good psychological well-being can help reduce mental distraction.
Reshma C, Aruna Polisetty
openaire +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
The impact of work-family conflict on working women in Taiwan : the effects of organizational support [PDF]
, 2007 A cross-sectional survey was undertaken to examine the impact of organizational support on work-family conflict experienced by Taiwanese working women. A stress model of work and family interference was applied in the Taiwanese context; the current study
Lu, Yu-Ying
core
DanadyaksaThis study examines the effects of Work–Family Conflict and Family–Work Conflict on Job Satisfaction, with Work–Life Balance as a mediating variable among employees of PT. Wahyu Wisata Mandalika.
Maya Okyantari, Mukmin Suryatni
doaj +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source