Results 71 to 80 of about 16,465,093 (249)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Work-family conflict and enrichment : a study of college coaches [PDF]
, 2008 textThe current work-family literature strongly emphasizes the conflict between the multiple roles that workers and parents assume. This conflict literature leaves readers with the impression that individuals are experiencing stress to a level that ...
Schenewark, Jarrod Denman
core
Europe's Journal of Psychology, 2020 Dual-income families are challenged by several issues in terms of conciliation between the working environment, the family context and the management of children.
Alessandro Lo Presti +4 more
doaj +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Australian Journal of Psychology, 2020 Objective: The aim of the study was to explore the possible indirect effect of subjective career success on the relationship between work–family enrichment and job satisfaction and work–family enrichment and work engagement.
Eileen Koekemoer +2 more
doaj +1 more source
The Consequences of Work–Family Enrichment in Families on the Behaviour of Children
Social Sciences, 2020 This study considers the spillover effect of work-family enrichment in parents on the behaviour of their children. Using a mediation model with parental well-being and parenting styles, the study unravels the associations between a positive perspective ...
Annelies Van den Eynde +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Research status quo of work family enrichment in nursing field
Huli yanjiu, 2021 In this paper，connotation，theoretical basis，and measurement tools of work family enrichment were sorted out firstly.Antecedent variables and outcome variables of work family enrichment were also summarized.Finally，research status quo of work family ...
WU Meiliyang, CHEN Ye, ZENG Tieying
doaj
Family incivility and work-engagement: moderated mediation model of personal resources and family-work enrichment. [PDF]
Curr Psychol, 2022 Gopalan N, Pattusamy M, Goodman S.
europepmc +1 more source