Results 31 to 40 of about 214,797 (305)
Environmental Research LettersFamine still exists in this world, hindering the achievement of Sustainable Development Goal 2: zero hunger. The history and the mechanisms of famine have been broadly studied; however, few studies have focused on quantitative and long-term analyses of ...
Soma Funahashi +2 more
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CEOs’ early famine experience, managerial discretion and corporate social responsibility
Humanities & Social Sciences Communications, 2023 Corporate social responsibility (CSR) reflects entrepreneurs’ early life experiences in reality. Based on imprinting theory and upper echelons theory, this paper examines the impact of a CEO’s early famine experience on CSR, analyzes the moderating ...
Zhaocheng Xu
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski +9 more
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How Chief Executive Officers’ first-hand experience of the Great Chinese Famine affects risk-taking?
Humanities & Social Sciences Communications, 2023 To understand the influence of Chief Executive Officers’ (CEOs) early life experiences on their firms’ strategic decision-making, here we explore the impacts of CEOs’ experience of the Great Chinese Famine (1959–1961) on their cognitions and firm risk ...
Dayuan Li, Chen Huang, Ding Wang
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
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Frontiers in Behavioral Neuroscience, 2016 Objective: To investigate whether exposure to the Chinese Famine in different life stages of early life is associated with cognitive functioning decline in adulthood.Methods: We recruited 1366 adults born between 1952 and 1964 and divided them into fetal-
Chao Wang +7 more
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Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Exposure to Chinese famine in early life and the risk of multimorbidity in adulthood
BMC Public HealthObjectives Previous studies had reported the association between famine exposure in early life and subsequent non-communicable diseases risk. In current study, we aimed to evaluate the associations between famine exposure on multimorbidity prevalence and
Jiahui Zhang +3 more
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Frontiers in Endocrinology, 2022 Background & AimsPrimary hyperparathyroidism(PHPT) has been evolving into a milder asymptomatic disease. No study has assessed the association between famine exposure and such a shift. We aim to explore the effects of China’s Great Famine exposure on
Tian-jiao Yuan +21 more
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Aging and Cancer, EarlyView.ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source