Results 131 to 140 of about 8,375 (152)
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The Fanconi Anemia Complementation Group A Protein Contains a Peroxidase Domain
Molecular Genetics and Metabolism, 1998Computational analysis of the Fanconi anemia (FA) complementation group A protein suggests that it contains a peroxidase domain. FA proteins may be part of a general mechanism that protects cells from oxidative damage.
I S, Mian, M J, Moser
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Biochemical and Biophysical Research Communications, 1999
The function of the Fanconi anemia complementation group A (FANCA) protein remains unclear. To investigate possible protein-protein interactions, we performed yeast two-hybrid screening using a FANCA fragment as bait. Sorting nexin 5 (SNX5), a new member of the human SNX family, was identified as a putative FANCA-binding protein.
T, Otsuki +3 more
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The function of the Fanconi anemia complementation group A (FANCA) protein remains unclear. To investigate possible protein-protein interactions, we performed yeast two-hybrid screening using a FANCA fragment as bait. Sorting nexin 5 (SNX5), a new member of the human SNX family, was identified as a putative FANCA-binding protein.
T, Otsuki +3 more
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Intracellular Localization of the Fanconi Anemia Complementation Group A Protein
Biochemical and Biophysical Research Communications, 1999Mutations in the Fanconi anemia (FA) complementation group A (FANCA) gene leads to bone marrow failure, developmental abnormalities and cancer predisposition. To map the intracellular site of FANCA, we constructed a plasmid vector which linked in-frame the enhanced green fluorescent protein (EGFP cDNA) to the 5' end of the FANCA cDNA (pDAS-3).
C E, Walsh, M R, Yountz, D A, Simpson
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Molecular Genetics and Metabolism, 2001
Fanconi anemia (FA) is an autosomal recessive disorder manifested by chromosomal breakage, birth defects, and susceptibility to bone marrow failure and cancer. At least seven complementation groups have been identified, and the genes defective in four groups have been cloned. The most common subtype is complementation group A.
J, Ren, H, Youssoufian
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Fanconi anemia (FA) is an autosomal recessive disorder manifested by chromosomal breakage, birth defects, and susceptibility to bone marrow failure and cancer. At least seven complementation groups have been identified, and the genes defective in four groups have been cloned. The most common subtype is complementation group A.
J, Ren, H, Youssoufian
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Experimental Hematology, 2015
Bone marrow failure in Fanconi anemia (FA) has been linked in part to overproduction of inflammatory cytokines, to which FA stem and progenitor cells are hypersensitive. In cell lines and murine models p38 mitogen-activated protein kinase (MAPK)-dependent tumor necrosis factor α (TNF-α) overexpression can be induced by the Toll-like receptors (TLRs) 4 ...
Johanna, Svahn +10 more
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Bone marrow failure in Fanconi anemia (FA) has been linked in part to overproduction of inflammatory cytokines, to which FA stem and progenitor cells are hypersensitive. In cell lines and murine models p38 mitogen-activated protein kinase (MAPK)-dependent tumor necrosis factor α (TNF-α) overexpression can be induced by the Toll-like receptors (TLRs) 4 ...
Johanna, Svahn +10 more
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X-linked inheritance of Fanconi anemia complementation group B
Nature Genetics, 2004Maureen Hoatlin +2 more
exaly
The DNA helicase BRIP1 is defective in Fanconi anemia complementation group J
Nature Genetics, 2005Quinten Waisfisz +2 more
exaly
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2005
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Validation of Fanconi anemia complementation Group A assignment using molecular analysis
Genetics in Medicine, 2009Markus Grompe, Glenn E Palomaki
exaly