Results 151 to 160 of about 6,800,049 (185)

Farnesoid X Receptor Agonist INT-787 Inhibits Hepatic Mitochondrial Dysfunction in a Diet-Induced ob/ob Mouse Model of MASH. [PDF]

Int J Mol Sci
Di Pasqua LG, Palladini G, Croce AC, Milanesi G, Cavallo M, Adorini L, Ferrigno A, Vairetti M.   +7 more
europepmc   +1 more source

Farnesoid X Receptor Agonist Tropifexor Improves Intestinal Defense Response and Epithelial Barrier Function in Neonatal Piglets Receiving Parenteral Nutrition. [PDF]

FASEB J
Zhao Y, Xiao Y, Jiang L, Wang Y, Liu Y, Zhang T, Cai W, Yan J.   +7 more
europepmc   +1 more source

A farnesoid X receptor T296I variant disrupts ligand-induced FXR activation and thus bile acid transport in progressive familial intrahepatic cholestasis. [PDF]

J Biol Chem
Behrendt A, Bastianelli A, Stindt J, Pfister ED, Sgodda M, Cantz T, Hook S, Gopalswamy M, Grau K, Brands S, Dröge C, Stalke A, Bonus M, Franke S, Baumann U, Keitel V, Gohlke H.   +16 more
europepmc   +1 more source

Ursodeoxycholic acid alleviates aortic aneurysm and dissection through the intestinal farnesoid X receptor/ceramide synthase 2 axis. [PDF]

Commun Biol
Zhang Z, Xie L, Lin X, He J, Xie Y, Li J, Zhuang X, Tang L, Xie R, Wu Q, Qiu Z, Chen L.   +11 more
europepmc   +1 more source

[Retracted] Farnesoid X receptor inhibits proliferation of human colorectal cancer cells via the miR‑135A1/CCNG2 signaling pathway. [PDF]

Oncol Rep
Qiao P, Li S, Zhang H, Yao L, Wang F.
europepmc   +1 more source

Farnesoid X receptor: a potential key target for maintaining liver organoid growth. [PDF]

Biomater Transl
Bai H, Wu G, Shi Y, Han Z.
europepmc   +1 more source

The farnesoid X receptor activates transcription independently of RXR at non-canonical response elements. [PDF]

Nucleic Acids Res
van der Veen SW, Dijkstra JJ, Willemsen ECL, Houtman R, Milona A, Marchet N, Spit M, Hollman D, Zwartkruis FJT, Vermeulen M, Ramos Pittol JM, van Mil SWC.   +11 more
europepmc   +1 more source

The Molecular Mechanism of Farnesoid X Receptor Alleviating Glucose Intolerance in Turbot (Scophthalmus maximus). [PDF]

Cells
Qin G, Pan M, Huang D, Li X, Liu Y, Yu X, Mai K, Zhang W.   +7 more
europepmc   +1 more source

Farnesoid X receptor (FXR) as a potential therapeutic target for lung diseases: a narrative review. [PDF]

J Thorac Dis
Cao Y, Xu Y, Zhou J, Fu X, Zhang H, Du X, Liang S, Liu M.   +7 more
europepmc   +1 more source

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INT-787, a Novel Farnesoid X Receptor Agonist, in Healthy Volunteers: A Phase 1 Trial. [PDF]

Clin Transl Sci
Capozza T, Burkey J, Van De Wetering J, Kerb R, Callahan J, Kryzhanovskaya L, Erickson M.   +6 more
europepmc   +1 more source