Results 161 to 167 of about 5,098 (167)

CRYSTAL STRUCTURE OF RAT PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH THE NON-SUBSTRATE TETRAPEPTIDE INHIBITOR CVFM AND FARNESYL DIPHOSPHATE SUBSTRATE

, 2001
S. Long, P. Casey, L. Beese
semanticscholar   +1 more source

Evaluation of geranylazide and farnesylazide diphosphate for incorporation of prenylazides into a CAAX box-containing peptide using protein farnesyltransferase.

Journal of Peptide Research, 2005
M. W. Rose, N. D. Rose, J. Boggs, S. Lenevich, Juhua Xu, G. Barany, M. Distefano   +6 more
semanticscholar   +1 more source

Site-Selective Enzymatic Labeling of Designed Ankyrin Repeat Proteins Using Protein Farnesyltransferase.

Methods in molecular biology, 2019
Yi Zhang, Shelby A. Auger, J. Schaefer, A. Plückthun, M. Distefano   +4 more
semanticscholar   +1 more source

Farnesyltransferase inhibitors: a detailed chemical view on an elusive biological problem.

Current Medicinal Chemistry, 2008
S. Sousa, P. Fernandes, M. Ramos
semanticscholar   +1 more source

AuaA, a Membrane‐Bound Farnesyltransferase from Stigmatella aurantiaca, Catalyzes the Prenylation of 2‐Methyl‐4‐hydroxyquinoline in the Biosynthesis of Aurachins

ChemBioChem, 2011
Edyta Stec, D. Pistorius, R. Müller, Shu‐Ming Li   +3 more
semanticscholar   +1 more source

H-Ras peptide and protein substrates bind protein farnesyltransferase as an ionized thiolate.

Biochemistry, 1998
K. Hightower, Chih‐chin Huang, P. Casey, C. Fierke   +3 more
semanticscholar   +1 more source

3-Aminopyrrolidinone farnesyltransferase inhibitors: design of macrocyclic compounds with improved pharmacokinetics and excellent cell potency.

Journal of Medicinal Chemistry, 2002
I. M. Bell, S. N. Gallicchio, M. Abrams, L. Beese, D. Beshore, H. Bhimnathwala, M. Bogusky, C. Buser, J. Culberson, J. Davide, M. Ellis-Hutchings, C. Fernandes, J. Gibbs, S. Graham, K. Hamilton, G. Hartman, D. Heimbrook, C. Homnick, H. Huber, J. Huff, K. Kassahun, K. Koblan, N. Kohl, R. Lobell, J. Lynch, R. Robinson, A. D. Rodrigues, Jeffrey S. Taylor, E. Walsh, T. Williams, C. B. Zartman   +30 more
semanticscholar   +1 more source