Results 131 to 140 of about 6,405 (188)

Membrane-associated Rhes-Slc4a7 complex orchestrates tunneling nanotube formation and mutant Huntingtin spread. [PDF]

Sci Adv
Dagar S, Fernandez A, Ramírez-Jarquín UN, Lopez-Huerta VG, Mirza E, Mohapatra C, Zuniga I, Urban NT, Crynen G, Tsaprailis G, Subramaniam S.   +10 more
europepmc   +1 more source

Combination of farnesyl-transferase inhibition with KRAS G12D targeting breaks down therapeutic resistance in pancreatic cancer. [PDF]

Pathol Oncol Res
Molnár E, Baranyi M, Szigeti K, Hegedűs L, Bordás F, Gábriel Z, Petényi G, Tóvári J, Hegedűs B, Tímár J.   +9 more
europepmc   +1 more source

Emerging KRAS G12D inhibitor in the treatment of digestive system tumors: opportunities and challenges. [PDF]

Transl Gastroenterol Hepatol
Wu X, Hayashi H, Tanizaki T, Sun Y, Iwatsuki M.   +4 more
europepmc   +1 more source

Farnesyltransferase inhibitor LB42708 disables oncogenic RAS signaling and overcomes gefitinib resistance in NSCLC via FTase α-subunit and RAS degradation. [PDF]

Cell Commun Signal
Luo G, Li D, Peng J, Liu R, Meng Y, Ward R, Zhang Y, Zhang X, Cui F, Wang J, Yang X, Chen M, Xu Y, Chen S, Jiang W, Zhang L, Li Y, Yang Y, Xiang C, Guo X, Dai J, Sang J, Xu TR, An S.   +23 more
europepmc   +1 more source

Uncovering protein prenylation in Th1 cells: novel prenylation sites and insights into statin and farnesyltransferase inhibition. [PDF]

BMC Biol
Koch J, Ruggia A, Beha C, Wipf I, Zhakparov D, Westermann P, Schmelzer S, Heider A, Fröhlich K, Baerenfaller K.   +9 more
europepmc   +1 more source

Optimized genetic tracers for viral mediated neuronal projection mapping. [PDF]

Cell Mol Biol Lett
Dulin JN, Ye L, Grider T, Rizzo A, Rosenzweig ES, Weber J, Ramakrishnan C, Hsueh B, Deisseroth K, Tuszynski MH, Gibbs D, Poplawski GHD.   +11 more
europepmc   +1 more source

Navigating lipid droplet proteins - part I: ER targeting routes of lipid droplet-destined membrane proteins. [PDF]

Biochem Soc Trans
Krauß LM, Schrul B.
europepmc   +1 more source

Clathrin mediated endocytosis targeting chimera for targeted membrane proteins degradation and enhance CAR-T cell anti-tumor therapy. [PDF]

Theranostics
Li Y, Zhou Z, Lv Y, Hu H, Chen M, Lei K, Gong C, Liu J, Yang L, Huang L, Liu W, Li J, Ye M, Zhu X, Huang K.   +14 more
europepmc   +1 more source

Sortase A-mediated farnesylation of Cdc42 in vitro

Tschirpke S, Hettema NM, Spitzbarth B, Eelkema R, Laan L.   +4 more
europepmc   +1 more source