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Characterization of Farnesyl Diphosphate Farnesyl Transferase 1 ( FDFT1 ) Expression In Cancer
Personalized Medicine, 2018To help characterize the FDFT1 gene and protein expression in cancer. Cholesterol represents an important structural component of lipid rafts. These specializations can be involved in pathways stimulating cell growth, survival and other processes active in cancer.
Tüzmen, Şükrü +8 more
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Farnesyl Diphosphate Synthase Assay
2014Farnesyl diphosphate synthase (FPS) catalyzes the sequential head-to-tail condensation of isopentenyl diphosphate (IPP, C5) with dimethylallyl diphosphate (DMAPP, C5) and geranyl diphosphate (GPP, C10) to produce farnesyl diphosphate (FPP, C15). This short-chain prenyl diphosphate constitutes a key branch-point of the isoprenoid biosynthetic pathway ...
Montserrat, Arró +2 more
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Expression cloning of farnesylated proteins
2001Publisher Summary The identification of novel prenylated proteins has most often involved the labeling of cultured cells with [3H] mevalonolactone that is enzymatically converted to [3H] farnesyl pyrophosphate (FPP) and [3H] geranylgeranyl pyrophosphate (GGPP) prior to being incorporated into protein.
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Farnesylation is involved in meristem organization in Arabidopsis
Planta, 2000Tammy Sage, P McCourt
exaly