Results 141 to 150 of about 9,367 (212)

KRAS4a and KRAS4b show distinct lipid-dependent regulation of RAS-RAF membrane dynamics. [PDF]

J Biol Chem
Georgouli K, Tempkin JOB, Stanton LG, Oppelstrup T, Shrestha R, Carpenter TS, Aydin F, Zhang X, Bhatia H, Yang Y, Van QN, Bonilla PA, Gulten G, Goswami D, Di Natale F, Chavez JR, Moon JY, Dharuman G, Hengartner NW, Simanshu DK, Tran TH, Nguyen K, Stanley CB, Van Essen B, Bremer PT, Lightstone FC, Stephen AG, Glosli JN, Gnanakaran S, Turbyville TJ, McCormick F, Nissley DV, Streitz FH, Ingólfsson HI.   +33 more
europepmc   +1 more source

Farnesyltransferase inhibitor LB42708 disables oncogenic RAS signaling and overcomes gefitinib resistance in NSCLC via FTase α-subunit and RAS degradation. [PDF]

Cell Commun Signal
Luo G, Li D, Peng J, Liu R, Meng Y, Ward R, Zhang Y, Zhang X, Cui F, Wang J, Yang X, Chen M, Xu Y, Chen S, Jiang W, Zhang L, Li Y, Yang Y, Xiang C, Guo X, Dai J, Sang J, Xu TR, An S.   +23 more
europepmc   +1 more source

Genetic and pharmacological modulation of lamin A farnesylation determines its function and turnover. [PDF]

Aging Cell
Foo MXR, Ong PF, Yap ZX, Maric M, Bong CJS, Dröge P, Burke B, Dreesen O.   +7 more
europepmc   +1 more source

Farnesyl Transferase Inhibitors as a Novel Strategy for Targeting KRAS-Dependent Cancers. [PDF]

ACS Med Chem Lett
Kargbo RB.
europepmc   +1 more source

Benzoate Drugs for Traumatic Brain Injury. [PDF]

J Clin Exp Immunol
Pahan S, Pahan K.
europepmc   +1 more source

Defining proteoform-specific interactions for drug targeting in a native cell signalling environment. [PDF]

Nat Chem
Lutomski CA, Bennett JL, El-Baba TJ, Wu D, Hinkle JD, Burnap SA, Liko I, Mullen C, Syka JEP, Struwe WB, Robinson CV.   +10 more
europepmc   +1 more source

Lamin A/C as a Molecular Link Between Nuclear Organization, Chromatin Dynamics, and Tumor Progression. [PDF]

Cells
Foglini C, Scotlandi K, Pasello M.
europepmc   +1 more source

Localization of the PelC and PelE effectors to the <i>Legionella</i>-containing vacuole through host-mediated prenylation and their role in intracellular proliferation. [PDF]

Infect Immun
Shin CJ, Price CTD, Da'as MSJ, Abu Kwaik Y.   +3 more
europepmc   +1 more source

Selection of specific and efficient siRNAs in new cellular model for Hutchinson-Gilford progeria syndrome therapy. [PDF]

Mol Ther Nucleic Acids
Dzianisava V, Piekarowicz K, Machowska M, Rzepecki R.   +3 more
europepmc   +1 more source

Alpha-Synuclein Inhibits the Secretion of Extracellular Vesicles through Disruptions in YKT6 Lipidation. [PDF]

J Neurosci
Tsunemi T, Ishiguro Y, Yoroisaka A, Feng D, Shimada T, Niiyama S, Sasazawa Y, Ishikawa K, Akamatsu W, Hattori N.   +9 more
europepmc   +1 more source