Results 161 to 170 of about 538,057 (302)

Kidney Hematopoietic Stem and Progenitor Cells Contribute to Myeloid Development and Pathology in Lupus Nephritis

Arthritis &Rheumatology, Accepted Article.
Objectives The hematopoietic system maintains homeostasis by balancing myeloid and lymphoid cell production in the bone marrow (BM). In response to increased hematopoietic demand, extramedullary hematopoiesis (EMH) may occur in non‐lymphoid organs. We investigated the role of EMH and kidney‐resident hematopoietic stem and progenitor cells (HSPCs) in ...
Hansol Yi, Seyoung Jung, Jeong Ho Joo, Young‐Eun Kim, Heounjeong Go, Yong‐Gil Kim, Chang‐Keun Lee, Bin Yoo, Jeong Seok Lee, Seokchan Hong   +9 more
wiley   +1 more source

Effects of Omega-3 Fatty Acids on High-Fat Diet-Induced Obesity: A Systematic Review of Rodent Studies. [PDF]

Nutr Rev
Saban Güler M, Yıldıran H.
europepmc   +1 more source

Main factors associated with variability in the assessment of the objective response rate. A re‐analysis of the PHEREXA phase 3 clinical trial

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Local investigators (LIs) overestimate the objective response rate (ORR) in comparison to Blinded Independent Central Reviewers (BICR) in oncology. In this study, we re‐analysed data obtained in the PHEREXA trial (NCT01026142) with the following aims: i) to confirm at the single‐patient level the discrepancy observed by analysing ...
Gennaro Daniele, Tommaso Giovagnoli, Pierluigi Navarra, Cinzia Dello Russo   +3 more
wiley   +1 more source

GTPase-activating protein DLC1 spatio-temporally regulates Rho signaling. [PDF]

Elife
Hinderling L, Heydasch M, Rochat G, Dubied L, van Unen J, Dobrzynski M, Pertz O.   +6 more
europepmc   +1 more source

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

British Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher, Amina Džidić‐Krivić, Emma Pinjic, Nejra Selak, Kanita Omerbasic, Alexandar Chupin, Andrej Belancic, Almir Fajkic   +7 more
wiley   +1 more source

Placental transport dysfunction in omega-3 and omega-6 fatty acid in patients with gestational diabetes mellitus. [PDF]

Ann Med
Long W, Guo F, Yao J, Wei Q, Yin L, Xu J, Cao X.   +6 more
europepmc   +1 more source

Limited Area Coverage/high Resolution Picture Transmission, LAC/HRPT tape conversion processor user's manual [PDF]

The program, LACSEG, converts LAC/HRPT data tapes to the CSC defined Universal format.
Obrien, S. O.
core   +1 more source

Practice, knowledge and attitude of physicians and pharmacists towards the spontaneous reporting system of adverse drug reactions in Switzerland

British Journal of Clinical Pharmacology, EarlyView.
Introduction Introduction Reporting adverse drug reactions (ADRs) is essential for detecting drug risks. Despite legal obligations in Switzerland, underreporting remains an issue. This study assessed practice, knowledge and attitudes towards the spontaneous ADR reporting system among physicians and pharmacists.
Fiona A. Strobel, Thomas Stammschulte, Patrick E. Beeler   +2 more
wiley   +1 more source

Oxygen and glucose supplementation increases rates of linear growth and cell proliferation in growth-restricted fetal sheep. [PDF]

J Physiol
Varela M, Chrisenberry DB, Johnson EH, Luna-Ramirez RI, Tracy AR, Kathuria S, Zhao W, Anderson MJ, Brown LD, Limesand SW.   +9 more
europepmc   +1 more source

TNFSF13 insufficiency disrupts human colonic epithelial cell growth and associated B cell dynamics. [PDF]

J Clin Invest
Ma X, Nettleford SK, Tian Y, Dawany N, Kondo A, Li Y, Maurer K, Karakasheva TA, Shraim R, Williams PA, Parham LR, Simon LA, Danan CH, Conrad MA, Piccoli DA, Devoto M, Romberg N, Sullivan KE, Kaestner KH, Kelsen JR, Hamilton KE.   +20 more
europepmc   +1 more source