Results 101 to 110 of about 123,724 (326)

Death receptor 5 expression is inversely correlated with prostate cancer progression. [PDF]

open access: yes, 2014
Prostate carcinoma (PCa) is one of the most common cancers in men. Prostate-specific antigen (PSA) has been widely used to predict the outcome of PCa and screening with PSA has resulted in a decline in mortality. However, PSA is not an optimal prognostic
Antonio-Andres, Gabriela   +10 more
core   +1 more source

Real‐Time, Label‐Free Classification of Cell Death Pathways via Holotomography‐Based Deep Learning Framework

open access: yesAdvanced Intelligent Systems, EarlyView.
A 3D holotomography system coupled with a deep learning model distinguishes how cells die—apoptosis, necroptosis or necrosis—without any fluorescent labels. Training on refractive index maps of HeLa cells yields 97% accuracy and flags necroptosis hours before chemical dyes.
Minwook Kim   +8 more
wiley   +1 more source

Engineering Tertiary Lymphoid Structures: Nanomedicine, Bioengineering, and Biomaterials for Precision Immunotherapy

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review explains how biomaterials and nanoparticles can be used to induce or modulate tertiary lymphoid structures (TLSs), which are ectopic immune hubs that form in nonlymphoid tissues during chronic disease and cancer. By comparing different methods, the article highlights design principles for modeling TLSs or recapitulating specific TLS ...
Shaza Karaman, Mei ElGindi, Jeremy Teo
wiley   +1 more source

Impaired Fas-Fas Ligand Interactions Result in Greater Recurrent Herpetic Stromal Keratitis in Mice

open access: yesJournal of Immunology Research, 2015
Herpes simplex virus-1 (HSV-1) infection of the cornea leads to a potentially blinding condition termed herpetic stromal keratitis (HSK). Clinical studies have indicated that disease is primarily associated with recurrent HSK following reactivation of a ...
Xiao-Tang Yin   +7 more
doaj   +1 more source

Effect of adjuvant therapy with ginkgo-damole on apoptosis, nerve injury and platelet aggregation of patients with acute cerebral infarction

open access: yesJournal of Acute Disease, 2017
Objective: To investigate the effect of adjuvant therapy with ginkgo-damole on apoptosis, nerve injury and platelet aggregation of patients with acute cerebral infarction.
Zhi-Yong Lu
doaj   +1 more source

Az SHP1 szerepe a Fas közvetített jelátviteli folyamatokban = The role of SHP1 in Fas mediated signaling [PDF]

open access: yes, 2008
Az apoptózis a sejtek elhalásának egyik legintenzívebben tanulmányozott, legjobban ismert formája. A sejthalált indukáló receptorok, köztük az általunk vizsgált Fas receptor, illetve az ezek által kiváltott jelet továbbító molekulák az apoptózis kutatás
Koncz, Gábor
core  

Inhibition of death receptor signals by cellular FLIP. [PDF]

open access: yes, 1997
The widely expressed protein Fas is a member of the tumour necrosis factor receptor family which can trigger apoptosis. However, Fas surface expression does not necessarily render cells susceptible to Fas ligand-induced death signals, indicating that ...
Bodmer, J.L.   +12 more
core   +1 more source

SSZ‐13‐Zeolith mit Isolierten Co2+‐Zentren als ein Effizientes und Beständiges Katalysatorsystem für die Nichtoxidative Ethandehydrierung

open access: yesAngewandte Chemie, EarlyView.
Für die nichtoxidative Ethandehydrierung zu Ethen wurden Katalysatoren mit isolierten Co2+‐Spezies in den 6MR‐ (Co2+‐Z2) und 8MR‐Fenstern ([Co(OH)]+‐Z) eines SSZ‐13‐Zeolithen hergestellt. Die Co2+‐Z2‐Spezies zeigten im Vergleich zu den [Co(OH)]+‐Spezies eine unerwartet hohe Ethenbildungsgeschwindikeit.
Qiyang Zhang   +5 more
wiley   +1 more source

Function of BID - a molecule of the bcl-2 family - in ischemic cell death in the brain [PDF]

open access: yes, 2002
Mitochondrial mechanisms, particularly the release of cytochrome c, play a role in the death of nerve and glial cells in cerebral ischemia. We have currently investigated whether BID, a proapoptotic molecule of the bcl-2 family and promoter of the ...
Amin-Hanjani, Sepideh   +5 more
core   +1 more source

Selbstassemblierte (Aza‐)BODIPY Farbstoffe für Biomedizinische In Vivo Bildgebung

open access: yesAngewandte Chemie, EarlyView.
Dieses Minireview klassifiziert (Aza‐)BODIPY‐Farbstoffe anhand ihrer molekularen Stapelungsmodi und Aggregattypen (H‐, oblique‐ oder J‐Typ) in wässrigen Medien und setzt diese Merkmale in Beziehung zu ihrer multimodalen Bildgebungsleistung. Durch die Verknüpfung von molekularem Design, Exzitonenkopplung und pfadabhängiger Assemblierung stellen wir ...
Antonia Albers   +2 more
wiley   +1 more source

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