Results 11 to 20 of about 123,724 (326)

A Comparison of Fas-Fas Ligand Mediated Apoptosis with Clinical and Pathological Parameters in Larynx Cancers; Twenty Years After Laryngectomy

open access: yesThe Turkish Journal of Ear Nose and Throat, 2022
Objective: Larynx cancer constitutes 2% of all cancers in adults with 96% of larynx malignancies being squamous cell carcinoma (SHC). Apoptosis is a cell death mechanism that is quite different from necrosis.
Ahmet Mert Bilgili, Tolga Ersözlü
doaj   +1 more source

Fas ligand, death gene [PDF]

open access: yesCell Death & Differentiation, 1999
The concept of death genes goes back to the early days of programmed cell death, when a researcher's model system was required to be dependent on transcription of the dying cell in order to qualify as apoptosis. In 1987 Andrew Wyllie,1 one of the pioneers of cell death research, outlined four 'cardinal elements' of apoptosis: one of which was a ...
M J, Pinkoski, D R, Green
openaire   +2 more sources

Posttranslational regulation of Fas ligand function

open access: yesCell Communication and Signaling, 2008
The TNF superfamily member Fas ligand acts as a prototypic death factor. Due to its ability to induce apoptosis in Fas (APO-1, CD95) expressing cells, Fas ligand participates in essential effector functions of the immune system. It is involved in natural
Paulsen Maren   +3 more
doaj   +1 more source

Focal adhesions are foci for tyrosine-based signal transduction via GIV/Girdin and G proteins. [PDF]

open access: yes, 2015
GIV/Girdin is a multimodular signal transducer and a bona fide metastasis-related protein. As a guanidine exchange factor (GEF), GIV modulates signals initiated by growth factors (chemical signals) by activating the G protein Gαi.
Ghosh, Pradipta   +6 more
core   +1 more source

The In Situ Hybridization Expression of Fas and Fas Ligand (FasL) in Trophoblastic tissue of Aborted Women Compared with Normal Pregnancy.

open access: yesمجلة كلية الطب, 2009
Background: Estimation of the in situ expression of Fas and Fas ligand (FasL) in aborted women compared with normal human pregnancy . Patients and Methods: A technique utilizing in situ hybridization(ISH) was performed to detect and determine the in situ
Amal H. Salman   +2 more
doaj   +1 more source

Expression of Fas Ligand is Higher in Early Stage Cervical Cancer with Lymph Nodes Metastasis

open access: yesIndonesian Journal of Obstetrics and Gynecology, 2012
Objective: To know whether the expression of Fas Ligand has correlation with incidene of metastasis of pelvic lymph node and lymph-vascular stromal invasion (LVSI).
Yahya Irwanto
doaj   +1 more source

cMet and fas receptor interaction inhibits death-inducing signaling complex formation in endothelial cells [PDF]

open access: yes, 2005
Fas receptor is constitutively expressed on endothelial cells; however, these cells are highly resistant to Fas-mediated apoptosis. In this study, we examined death-inducing signaling complex (DISC) formation in endothelial cells after Fas receptor ...
Brady, H.J.M., Smyth, L.A.
core   +1 more source

Expression of Fas antigen and Fas ligand in bronchoalveolar lavage from silicosis patients

open access: yesMediators of Inflammation, 2003
Objective: To understand the role of apoptosis through Fas/Fas ligand (FasL) interaction in the pathogenesis of silicosis, we examined the expression of Fas antigen, FasL and apoptosis in bronchoalveolar lavage fluid lymphocytes obtained from patients ...
Agnès Hamzaoui   +3 more
doaj   +1 more source

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