Results 21 to 30 of about 1,159,722 (286)
Expression of Fas antigen and Fas ligand in bronchoalveolar lavage from silicosis patients
Mediators of Inflammation, 2003 Objective: To understand the role of apoptosis through Fas/Fas ligand (FasL) interaction in the pathogenesis of silicosis, we examined the expression of Fas antigen, FasL and apoptosis in bronchoalveolar lavage fluid lymphocytes obtained from patients ...
Agnès Hamzaoui +3 more
doaj +1 more source
Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening
BMC Immunology, 2009 Background - Fas ligand is a cytotoxic effector molecule of T and NK cells which is characterized by an intracellular N-terminal polyproline region that serves as a docking site for SH3 and WW domain proteins.
Lettau Marcus +2 more
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Apoptosis of HeLa and CaSki cell lines incubated with All-trans retinoid acid.
Folia Histochemica et Cytobiologica, 2010 The aim of the study was to evaluate the concentrations of a soluble form of APO-1/Fas antigen (sFas, CD95) and a soluble Ligand for APO-1/Fas antigen (sCD95L, sFasL) in supernatants from CaSki and HeLa cell line cultures after the incubation with All ...
Jan Oleszczuk +6 more
doaj +1 more source
The Fas ligand/Fas system in renal injury [PDF]
Nephrology Dialysis Transplantation, 1999 The FasL-Fas system regulates renal cell apoptosis, as well as the immune and inflammatory responses. Evidence that FasL and Fas participate in renal injury may be summarized along modified Koch's postulates (Table 1): (i) FasL is expressed by renal cells and during renal injury, (ii) activation of the Fas receptor promotes apoptosis of cultured renal ...
A, Ortiz, C, Lorz, J, Egido
openaire +2 more sources
Haematologica, 2015 Autoimmune lymphoproliferative syndrome is frequently caused by mutations in genes involved in the Fas death receptor pathway, but for 20–30% of patients the genetic defect is unknown.
Schafiq Nabhani +13 more
doaj +1 more source
Expression Profile of Fas-Fas Ligand in Spiral Ganglion Cells During Apoptosis [PDF]
Clinical and Experimental Otorhinolaryngology, 2014 ObjectivesTo examine the expression profile of Fas-Fas ligand (FasL) during glutamate (Glu)-induced spiral ganglion cell (SGC) apoptosis.MethodsCultured SGCs were treated with 10-mM, 25-mM, and 50-mM concentrations of Glu and incubated for 24 or 48 hours.
Tae Woo Gu +6 more
doaj +1 more source
Haematologica, 2013 Clinical and genetic heterogeneity renders confirmation or exclusion of autoimmune lymphoproliferative syndrome difficult. To re-evaluate and improve the currently suggested diagnostic approach to patients with suspected FAS mutation, the most frequent ...
Anne Rensing-Ehl +36 more
doaj +1 more source
Artificial Cells, Nanomedicine, and Biotechnology, 2019 In this study, sevoflurane (SF) loaded, Fas ligand conjugated reduced graphene oxide (rGO) system is fabricated as a therapeutic agent to target brain ischaemic region. The fluorescence investigation of mice brain denoted that the encapsulated SF in rGOs
Qinjuan Wu, Mingfeng Qin, Kun Zhang
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EXPRESSION OF FAS PROTEIN (CD95) AND FAS LIGAND IN LIVER TISSUE OF PATIENTS WITH HCV-INDUCED CHRONIC LIVER DISEASE AND ITS CORRELATION WITH THE DISEASE PROGRESSION [PDF]
Journal of the Egyptian Society of Parasitology, 2013 This study evaluated hepatic expression of both Fas and Fas ligand (FasL) in patients with hepatitis c virus (HCV)-induced chronic liver disease and its correlation with the histopathological activity and laboratory parameters as an early predictorof ...
Y. EL-DESSOUKY +4 more
doaj +1 more source
Fas induces apoptosis in human coronary artery endothelial cells in vitro
BMC Cell Biology, 2004 Background Published work suggests that some types of endothelial cells undergo apoptosis in response to ligation of the receptor Fas (CD95, APO1) but other types are resistant.
Wang Rongqi +5 more
doaj +1 more source