Results 21 to 30 of about 59,326 (211)
Haematologica, 2015 Autoimmune lymphoproliferative syndrome is frequently caused by mutations in genes involved in the Fas death receptor pathway, but for 20–30% of patients the genetic defect is unknown.
Schafiq Nabhani +13 more
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Expression Profile of Fas-Fas Ligand in Spiral Ganglion Cells During Apoptosis [PDF]
Clinical and Experimental Otorhinolaryngology, 2014 ObjectivesTo examine the expression profile of Fas-Fas ligand (FasL) during glutamate (Glu)-induced spiral ganglion cell (SGC) apoptosis.MethodsCultured SGCs were treated with 10-mM, 25-mM, and 50-mM concentrations of Glu and incubated for 24 or 48 hours.
Tae Woo Gu +6 more
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Haematologica, 2013 Clinical and genetic heterogeneity renders confirmation or exclusion of autoimmune lymphoproliferative syndrome difficult. To re-evaluate and improve the currently suggested diagnostic approach to patients with suspected FAS mutation, the most frequent ...
Anne Rensing-Ehl +36 more
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Artificial Cells, Nanomedicine, and Biotechnology, 2019 In this study, sevoflurane (SF) loaded, Fas ligand conjugated reduced graphene oxide (rGO) system is fabricated as a therapeutic agent to target brain ischaemic region. The fluorescence investigation of mice brain denoted that the encapsulated SF in rGOs
Qinjuan Wu, Mingfeng Qin, Kun Zhang
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EXPRESSION OF FAS PROTEIN (CD95) AND FAS LIGAND IN LIVER TISSUE OF PATIENTS WITH HCV-INDUCED CHRONIC LIVER DISEASE AND ITS CORRELATION WITH THE DISEASE PROGRESSION [PDF]
Journal of the Egyptian Society of Parasitology, 2013 This study evaluated hepatic expression of both Fas and Fas ligand (FasL) in patients with hepatitis c virus (HCV)-induced chronic liver disease and its correlation with the histopathological activity and laboratory parameters as an early predictorof ...
Y. EL-DESSOUKY +4 more
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Fas induces apoptosis in human coronary artery endothelial cells in vitro
BMC Cell Biology, 2004 Background Published work suggests that some types of endothelial cells undergo apoptosis in response to ligation of the receptor Fas (CD95, APO1) but other types are resistant.
Wang Rongqi +5 more
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European Journal of Histochemistry, 2010 Mouse monoclonal anti-Fas (CD95) antibody clone CH-11 has been widely used in research on apoptosis. CH-11 has the ability to bind to Fas protein on cell surface and induce apoptosis.
H. Sawai, N. Domae
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Fas-Fas Ligand: checkpoint of T cell functions in multiple sclerosis
Frontiers in Immunology, 2016 Fas and Fas Ligand (FasL) are two molecules involved in regulation of cell death. Their interaction leads to apoptosis of thymocytes that fail to rearrange correctly their T cell receptor genes (TCR) and of those that recognize self-antigens, a process ...
Elisabetta Volpe +3 more
doaj +1 more source
Significance of Fas and Fas ligand in tuberculous lymphadenitis
Immunology, 2005 SummaryThe Fas/Fas‐ligand (FasL) system plays an important role in regulation of apoptosis and the immune response, and is exploited by mycobacteria to evade the immune response. This study was performed to investigate the distribution and levels of FasL and Fas in lymph node granulomas and sera of tuberculous lymphadenitis patients by ...
Tehmina, Mustafa +4 more
openaire +3 more sources
Fas-ligand: Privilege and peril [PDF]
Proceedings of the National Academy of Sciences, 1997 Meanwhile, FasL was shown to play other roles in the body. As discussed in more detail below, activated cytotoxic T lymphocytes (and other cells) often express high levels of FasL and the ability of FasL to kill cells bearing Fas accounts for some destructive effects mediated by these cells.
D R, Green, C F, Ware
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