Results 21 to 30 of about 598,280 (274)

Apoptosis of HeLa and CaSki cell lines incubated with All-trans retinoid acid.

open access: yesFolia Histochemica et Cytobiologica, 2010
The aim of the study was to evaluate the concentrations of a soluble form of APO-1/Fas antigen (sFas, CD95) and a soluble Ligand for APO-1/Fas antigen (sCD95L, sFasL) in supernatants from CaSki and HeLa cell line cultures after the incubation with All ...
Jan Oleszczuk   +6 more
doaj   +1 more source

Lipocalin‐2 activates hepatic stellate cells and promotes nonalcoholic steatohepatitis in high‐fat diet–fed Ob/Ob mice

open access: yesHepatology, EarlyView., 2022
Graphical summary of obesity‐induced NASH progression by LCN2 targeted to HSC activation. Abstract Background and Aims In obesity and type 2 diabetes mellitus, leptin promotes insulin resistance and contributes to the progression of NASH via activation of hepatic stellate cells (HSCs).
Kyung Eun Kim   +12 more
wiley   +1 more source

Deregulation of Fas ligand expression as a novel cause of autoimmune lymphoproliferative syndrome-like disease

open access: yesHaematologica, 2015
Autoimmune lymphoproliferative syndrome is frequently caused by mutations in genes involved in the Fas death receptor pathway, but for 20–30% of patients the genetic defect is unknown.
Schafiq Nabhani   +13 more
doaj   +1 more source

Expression Profile of Fas-Fas Ligand in Spiral Ganglion Cells During Apoptosis [PDF]

open access: yesClinical and Experimental Otorhinolaryngology, 2014
ObjectivesTo examine the expression profile of Fas-Fas ligand (FasL) during glutamate (Glu)-induced spiral ganglion cell (SGC) apoptosis.MethodsCultured SGCs were treated with 10-mM, 25-mM, and 50-mM concentrations of Glu and incubated for 24 or 48 hours.
Tae Woo Gu   +6 more
doaj   +1 more source

AIF1+CSF1R+ MSCs, induced by TNF‐α, act to generate an inflammatory microenvironment and promote hepatocarcinogenesis

open access: yesHepatology, EarlyView., 2022
Mesenchymal stem cells subset, educated by TNF‐α, are involved to generate inflammatory microenvironment and promote hepatocarcinogenesis Abstract Background and Aims Increasing evidence suggests that mesenchymal stem cells (MSCs) home to injured local tissues and the tumor microenvironment in the liver.
Chen Zong   +9 more
wiley   +1 more source

The Fas ligand/Fas system in renal injury [PDF]

open access: yesNephrology Dialysis Transplantation, 1999
The FasL-Fas system regulates renal cell apoptosis, as well as the immune and inflammatory responses. Evidence that FasL and Fas participate in renal injury may be summarized along modified Koch's postulates (Table 1): (i) FasL is expressed by renal cells and during renal injury, (ii) activation of the Fas receptor promotes apoptosis of cultured renal ...
A, Ortiz, C, Lorz, J, Egido
openaire   +2 more sources

Sequential decisions on FAS sequencing guided by biomarkers in patients with lymphoproliferation and autoimmune cytopenia

open access: yesHaematologica, 2013
Clinical and genetic heterogeneity renders confirmation or exclusion of autoimmune lymphoproliferative syndrome difficult. To re-evaluate and improve the currently suggested diagnostic approach to patients with suspected FAS mutation, the most frequent ...
Anne Rensing-Ehl   +36 more
doaj   +1 more source

Synthesis of sevoflurane loaded reduced graphene oxide nanoparticles system for neuroprotective effects for preconditioning against focal cerebral ischaemia

open access: yesArtificial Cells, Nanomedicine, and Biotechnology, 2019
In this study, sevoflurane (SF) loaded, Fas ligand conjugated reduced graphene oxide (rGO) system is fabricated as a therapeutic agent to target brain ischaemic region. The fluorescence investigation of mice brain denoted that the encapsulated SF in rGOs
Qinjuan Wu, Mingfeng Qin, Kun Zhang
doaj   +1 more source

EXPRESSION OF FAS PROTEIN (CD95) AND FAS LIGAND IN LIVER TISSUE OF PATIENTS WITH HCV-INDUCED CHRONIC LIVER DISEASE AND ITS CORRELATION WITH THE DISEASE PROGRESSION [PDF]

open access: yesJournal of the Egyptian Society of Parasitology, 2013
This study evaluated hepatic expression of both Fas and Fas ligand (FasL) in patients with hepatitis c virus (HCV)-induced chronic liver disease and its correlation with the histopathological activity and laboratory parameters as an early predictorof ...
Y. EL-DESSOUKY   +4 more
doaj   +1 more source

Significance of Fas and Fas ligand in tuberculous lymphadenitis

open access: yesImmunology, 2005
SummaryThe Fas/Fas‐ligand (FasL) system plays an important role in regulation of apoptosis and the immune response, and is exploited by mycobacteria to evade the immune response. This study was performed to investigate the distribution and levels of FasL and Fas in lymph node granulomas and sera of tuberculous lymphadenitis patients by ...
Tehmina, Mustafa   +4 more
openaire   +3 more sources

Home - About - Disclaimer - Privacy