Results 31 to 40 of about 1,159,722 (286)
European Journal of Histochemistry, 2010 Mouse monoclonal anti-Fas (CD95) antibody clone CH-11 has been widely used in research on apoptosis. CH-11 has the ability to bind to Fas protein on cell surface and induce apoptosis.
H. Sawai, N. Domae
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Mesenchymal Stem Cell-Induced Immunoregulation Involves Fas Ligand/Fas-Mediated T Cell Apoptosis
Cell Stem Cell, 2012 SUMMARY Systemic infusion of bone marrow mesenchymal stem cells (BMMSCs) shows therapeutic benefit for a variety of autoimmune diseases, but the underlying mechanisms are poorly understood.
K. Akiyama +9 more
semanticscholar +1 more source
Significance of Fas and Fas ligand in tuberculous lymphadenitis
Immunology, 2005 SummaryThe Fas/Fas‐ligand (FasL) system plays an important role in regulation of apoptosis and the immune response, and is exploited by mycobacteria to evade the immune response. This study was performed to investigate the distribution and levels of FasL and Fas in lymph node granulomas and sera of tuberculous lymphadenitis patients by ...
Tehmina, Mustafa +4 more
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sFasL-mediated induction of neutrophil activation in patients with type 2 diabetes mellitus. [PDF]
PLoS ONE, 2018 Fas/Fas ligand system was shown to be related to insulin resistance and type 2 diabetes mellitus (T2DM). However, the role of soluble Fas ligand (sFasL) in functioning of immune cells in type 2 diabetes mellitus (T2DM) has not been studied yet.
Sona Margaryan +5 more
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Fas ligand mediates activation-induced cell death in human T lymphocytes
Journal of Experimental Medicine, 1995 A significant proportion of previously activated human T cells undergo apoptosis when triggered through the CD3/T cell receptor complex, a process termed activation-induced cell death (AICD).
G. Alderson +9 more
semanticscholar +1 more source
Fas-mediated apoptosis and peripheral polyneuropathy in type 2 diabetes mellitus
Egyptian Rheumatology and Rehabilitation, 2019 Objective To evaluate the role of soluble Fas (sFas) and soluble Fas ligand (sFasL) in the pathogenesis of distal symmetrical polyneuropathy (DSPN) in patients with type 2 diabetes mellitus, and to analyze the relationship between these apoptotic markers
Mowaffak M Abd Elhameed +5 more
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BMC Immunology, 2023 Background Patients with Sjögren’s syndrome, like other patients with autoimmune disorders, display dysregulation in the function of their immune system. Fas and Fas Ligand (FasL) are among the dysregulated proteins. Methods We studied Fas and FasL on IL-
Irena Lindrova +9 more
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Fas-ligand: Privilege and peril [PDF]
Proceedings of the National Academy of Sciences, 1997 Meanwhile, FasL was shown to play other roles in the body. As discussed in more detail below, activated cytotoxic T lymphocytes (and other cells) often express high levels of FasL and the ability of FasL to kill cells bearing Fas accounts for some destructive effects mediated by these cells.
D R, Green, C F, Ware
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The Fas counterattack: Fas-mediated T cell killing by colon cancer cells expressing Fas ligand
Journal of Experimental Medicine, 1996 Tumors escape immunological rejection by a diversity of mechanisms. In this report, we demonstrate that the colon cancer cell SW620 expresses functional Fas ligand (FasL), the triggering agent of Fas receptor (FasR)-mediated apoptosis within the immune ...
J. O'Connell +3 more
semanticscholar +1 more source
Expression of Fas ligand in retinoblastoma [PDF]
Cancer, 2004 AbstractBACKGROUNDThe importance of the Fas‐Fas ligand (FasL) mechanism for the immune evasion by tumors provided a strong rationale for the examination of FasL expression in retinoblastoma. In an earlier publication, the authors reported that invasive retinoblastomas decreased Fas expression.
Subramanian, Krishnakumar +6 more
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