Posttranslational regulation of Fas ligand function [PDF]
The TNF superfamily member Fas ligand acts as a prototypic death factor. Due to its ability to induce apoptosis in Fas (APO-1, CD95) expressing cells, Fas ligand participates in essential effector functions of the immune system. It is involved in natural
Paulsen Maren +3 more
doaj +2 more sources
The Fas - Fas Ligand apoptotic pathway [PDF]
Deep insight on The Fas - Fas Ligand apoptotic ...
P Bobé, Bobé, P
openaire +3 more sources
The role of soluble FMS-like tyrosine kinase (sFLT1) and FAS associated proteins in pregnancies complicated by preeclampsia and intrauterine growth restriction (IUGR). [PDF]
PhDCurrent thinking suggests that preeclampsia is associated with activation of the maternal vascular endothelium in response to factors released from the placenta due to placental hypoxia.
Fayyad, Abdalla Mustafa
core +4 more sources
Role of Apoptotic Biomarkers in Ameloblastoma and Dental Follicle
Objectives Ameloblastoma is an odontogenic neoplasm with locally aggressive behavior. Fas and FasL play important roles in apoptotic pathways. The aim of this study was to determine the possible role of expression of apoptotic pathways (Fas and FasL) in
Fatemeh Mashhadiabbas +2 more
doaj +1 more source
FAS-dependent cell death in α-synuclein transgenic oligodendrocyte models of multiple system atrophy [PDF]
Multiple system atrophy is a parkinsonian neurodegenerative disorder. It is cytopathologically characterized by accumulation of the protein p25α in cell bodies of oligodendrocytes followed by accumulation of aggregated α-synuclein in so-called glial ...
Christine L Kragh +52 more
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Background: Estimation of the in situ expression of Fas and Fas ligand (FasL) in aborted women compared with normal human pregnancy . Patients and Methods: A technique utilizing in situ hybridization(ISH) was performed to detect and determine the in situ
Amal H. Salman +2 more
doaj +1 more source
Expression of Fas Ligand is Higher in Early Stage Cervical Cancer with Lymph Nodes Metastasis
Objective: To know whether the expression of Fas Ligand has correlation with incidene of metastasis of pelvic lymph node and lymph-vascular stromal invasion (LVSI).
Yahya Irwanto
doaj +1 more source
Expression of Fas antigen and Fas ligand in bronchoalveolar lavage from silicosis patients
Objective: To understand the role of apoptosis through Fas/Fas ligand (FasL) interaction in the pathogenesis of silicosis, we examined the expression of Fas antigen, FasL and apoptosis in bronchoalveolar lavage fluid lymphocytes obtained from patients ...
Agnès Hamzaoui +3 more
doaj +1 more source
Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening
Background - Fas ligand is a cytotoxic effector molecule of T and NK cells which is characterized by an intracellular N-terminal polyproline region that serves as a docking site for SH3 and WW domain proteins.
Lettau Marcus +2 more
doaj +1 more source
Monocytes regulate the mechanism of T-cell death by inducing Fas-mediated apoptosis during bacterial infection. [PDF]
Monocytes and T-cells are critical to the host response to acute bacterial infection but monocytes are primarily viewed as amplifying the inflammatory signal.
Mitchell, T.J. +68 more
core +1 more source

