Results 11 to 20 of about 59,326 (211)

Role of Apoptotic Biomarkers in Ameloblastoma and Dental Follicle

open access: yesJournal of Dental School, 2021
Objectives Ameloblastoma is an odontogenic neoplasm with locally aggressive behavior. Fas and FasL play important roles in apoptotic pathways. The aim of this study was to determine the possible role of expression of apoptotic pathways (Fas and FasL) in
Fatemeh Mashhadiabbas   +2 more
doaj   +1 more source

Lipocalin‐2 activates hepatic stellate cells and promotes nonalcoholic steatohepatitis in high‐fat diet–fed Ob/Ob mice

open access: yesHepatology, EarlyView., 2022
Graphical summary of obesity‐induced NASH progression by LCN2 targeted to HSC activation. Abstract Background and Aims In obesity and type 2 diabetes mellitus, leptin promotes insulin resistance and contributes to the progression of NASH via activation of hepatic stellate cells (HSCs).
Kyung Eun Kim   +12 more
wiley   +1 more source

AIF1+CSF1R+ MSCs, induced by TNF‐α, act to generate an inflammatory microenvironment and promote hepatocarcinogenesis

open access: yesHepatology, EarlyView., 2022
Mesenchymal stem cells subset, educated by TNF‐α, are involved to generate inflammatory microenvironment and promote hepatocarcinogenesis Abstract Background and Aims Increasing evidence suggests that mesenchymal stem cells (MSCs) home to injured local tissues and the tumor microenvironment in the liver.
Chen Zong   +9 more
wiley   +1 more source

Posttranslational regulation of Fas ligand function

open access: yesCell Communication and Signaling, 2008
The TNF superfamily member Fas ligand acts as a prototypic death factor. Due to its ability to induce apoptosis in Fas (APO-1, CD95) expressing cells, Fas ligand participates in essential effector functions of the immune system. It is involved in natural
Paulsen Maren   +3 more
doaj   +1 more source

The In Situ Hybridization Expression of Fas and Fas Ligand (FasL) in Trophoblastic tissue of Aborted Women Compared with Normal Pregnancy.

open access: yesمجلة كلية الطب, 2009
Background: Estimation of the in situ expression of Fas and Fas ligand (FasL) in aborted women compared with normal human pregnancy . Patients and Methods: A technique utilizing in situ hybridization(ISH) was performed to detect and determine the in situ
Amal H. Salman   +2 more
doaj   +1 more source

Expression of Fas Ligand is Higher in Early Stage Cervical Cancer with Lymph Nodes Metastasis

open access: yesIndonesian Journal of Obstetrics and Gynecology, 2012
Objective: To know whether the expression of Fas Ligand has correlation with incidene of metastasis of pelvic lymph node and lymph-vascular stromal invasion (LVSI).
Yahya Irwanto
doaj   +1 more source

Expression of Fas antigen and Fas ligand in bronchoalveolar lavage from silicosis patients

open access: yesMediators of Inflammation, 2003
Objective: To understand the role of apoptosis through Fas/Fas ligand (FasL) interaction in the pathogenesis of silicosis, we examined the expression of Fas antigen, FasL and apoptosis in bronchoalveolar lavage fluid lymphocytes obtained from patients ...
Agnès Hamzaoui   +3 more
doaj   +1 more source

Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening

open access: yesBMC Immunology, 2009
Background - Fas ligand is a cytotoxic effector molecule of T and NK cells which is characterized by an intracellular N-terminal polyproline region that serves as a docking site for SH3 and WW domain proteins.
Lettau Marcus   +2 more
doaj   +1 more source

The Fas ligand/Fas system in renal injury [PDF]

open access: yesNephrology Dialysis Transplantation, 1999
The FasL-Fas system regulates renal cell apoptosis, as well as the immune and inflammatory responses. Evidence that FasL and Fas participate in renal injury may be summarized along modified Koch's postulates (Table 1): (i) FasL is expressed by renal cells and during renal injury, (ii) activation of the Fas receptor promotes apoptosis of cultured renal ...
A, Ortiz, C, Lorz, J, Egido
openaire   +2 more sources

Apoptosis of HeLa and CaSki cell lines incubated with All-trans retinoid acid.

open access: yesFolia Histochemica et Cytobiologica, 2010
The aim of the study was to evaluate the concentrations of a soluble form of APO-1/Fas antigen (sFas, CD95) and a soluble Ligand for APO-1/Fas antigen (sCD95L, sFasL) in supernatants from CaSki and HeLa cell line cultures after the incubation with All ...
Jan Oleszczuk   +6 more
doaj   +1 more source

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