Results 21 to 30 of about 115,762 (301)

Apoptosis of HeLa and CaSki cell lines incubated with All-trans retinoid acid.

open access: yesFolia Histochemica et Cytobiologica, 2010
The aim of the study was to evaluate the concentrations of a soluble form of APO-1/Fas antigen (sFas, CD95) and a soluble Ligand for APO-1/Fas antigen (sCD95L, sFasL) in supernatants from CaSki and HeLa cell line cultures after the incubation with All ...
Jan Oleszczuk   +6 more
doaj   +1 more source

Uterine spiral artery remodeling involves endothelial apoptosis induced by extravillous trophoblasts through Fas/FasL interactions. [PDF]

open access: yes, 2005
Objective— Invasion of uterine spiral arteries by extravillous trophoblasts in the first trimester of pregnancy results in loss of endothelial and musculoelastic layers.
Ashton, SV   +6 more
core   +1 more source

Deregulation of Fas ligand expression as a novel cause of autoimmune lymphoproliferative syndrome-like disease

open access: yesHaematologica, 2015
Autoimmune lymphoproliferative syndrome is frequently caused by mutations in genes involved in the Fas death receptor pathway, but for 20–30% of patients the genetic defect is unknown.
Schafiq Nabhani   +13 more
doaj   +1 more source

Expression Profile of Fas-Fas Ligand in Spiral Ganglion Cells During Apoptosis [PDF]

open access: yesClinical and Experimental Otorhinolaryngology, 2014
ObjectivesTo examine the expression profile of Fas-Fas ligand (FasL) during glutamate (Glu)-induced spiral ganglion cell (SGC) apoptosis.MethodsCultured SGCs were treated with 10-mM, 25-mM, and 50-mM concentrations of Glu and incubated for 24 or 48 hours.
Tae Woo Gu   +6 more
doaj   +1 more source

FAS-dependent cell death in α-synuclein transgenic oligodendrocyte models of multiple system atrophy [PDF]

open access: yes, 2013
Multiple system atrophy is a parkinsonian neurodegenerative disorder. It is cytopathologically characterized by accumulation of the protein p25α in cell bodies of oligodendrocytes followed by accumulation of aggregated α-synuclein in so-called glial ...
Fillon, Gwenaëlle   +13 more
core   +3 more sources

Sequential decisions on FAS sequencing guided by biomarkers in patients with lymphoproliferation and autoimmune cytopenia

open access: yesHaematologica, 2013
Clinical and genetic heterogeneity renders confirmation or exclusion of autoimmune lymphoproliferative syndrome difficult. To re-evaluate and improve the currently suggested diagnostic approach to patients with suspected FAS mutation, the most frequent ...
Anne Rensing-Ehl   +36 more
doaj   +1 more source

Monocytes regulate the mechanism of T-cell death by inducing Fas-mediated apoptosis during bacterial infection. [PDF]

open access: yes, 2012
Monocytes and T-cells are critical to the host response to acute bacterial infection but monocytes are primarily viewed as amplifying the inflammatory signal.
A Kadioglu   +64 more
core   +4 more sources

Marked mitigation of transplant vascular sclerosis in FasL(gld) (CD95L) mutant recipients. I. The role of alloantibodies in the development of chronic rejection [PDF]

open access: yes, 1999
Background. In the acute rejection of allografts, the interaction between Fas (CD95) and its ligand (FasL; CD95L) has been shown to be involved in mediating apoptotic cell death.
Aitouche, A   +7 more
core   +1 more source

Fas and Fas ligand in gut and liver [PDF]

open access: yesAmerican Journal of Physiology-Gastrointestinal and Liver Physiology, 2000
Apoptosis (programmed cell death) has been shown to play a major role in development and in the pathogenesis of numerous diseases. A principal mechanism of apoptosis is molecular interaction between surface molecules known as the “death receptors” and their ligands.
Pinkoski, Michael J.   +3 more
openaire   +3 more sources

Synthesis of sevoflurane loaded reduced graphene oxide nanoparticles system for neuroprotective effects for preconditioning against focal cerebral ischaemia

open access: yesArtificial Cells, Nanomedicine, and Biotechnology, 2019
In this study, sevoflurane (SF) loaded, Fas ligand conjugated reduced graphene oxide (rGO) system is fabricated as a therapeutic agent to target brain ischaemic region. The fluorescence investigation of mice brain denoted that the encapsulated SF in rGOs
Qinjuan Wu, Mingfeng Qin, Kun Zhang
doaj   +1 more source

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