Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening
BMC Immunology, 2009 Background - Fas ligand is a cytotoxic effector molecule of T and NK cells which is characterized by an intracellular N-terminal polyproline region that serves as a docking site for SH3 and WW domain proteins.
Lettau Marcus +2 more
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Primary and malignant cholangiocytes undergo CD40 mediated Fas dependent Apoptosis, but are insensitive to direct activation with exogenous fas ligand [PDF]
, 2010 Introduction Cholangiocarcinoma is a rare malignancy of the biliary tract, the incidence of which is rising, but the pathogenesis of which remains uncertain.
A Bergamo +67 more
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Marked mitigation of transplant vascular sclerosis in FasL(gld) (CD95L) mutant recipients. I. The role of alloantibodies in the development of chronic rejection [PDF]
, 1999 Background. In the acute rejection of allografts, the interaction between Fas (CD95) and its ligand (FasL; CD95L) has been shown to be involved in mediating apoptotic cell death.
Aitouche, A +7 more
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Apoptosis of HeLa and CaSki cell lines incubated with All-trans retinoid acid.
Folia Histochemica et Cytobiologica, 2010 The aim of the study was to evaluate the concentrations of a soluble form of APO-1/Fas antigen (sFas, CD95) and a soluble Ligand for APO-1/Fas antigen (sCD95L, sFasL) in supernatants from CaSki and HeLa cell line cultures after the incubation with All ...
Jan Oleszczuk +6 more
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Expression Profile of Fas-Fas Ligand in Spiral Ganglion Cells During Apoptosis [PDF]
Clinical and Experimental Otorhinolaryngology, 2014 ObjectivesTo examine the expression profile of Fas-Fas ligand (FasL) during glutamate (Glu)-induced spiral ganglion cell (SGC) apoptosis.MethodsCultured SGCs were treated with 10-mM, 25-mM, and 50-mM concentrations of Glu and incubated for 24 or 48 hours.
Tae Woo Gu +6 more
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Haematologica, 2015 Autoimmune lymphoproliferative syndrome is frequently caused by mutations in genes involved in the Fas death receptor pathway, but for 20–30% of patients the genetic defect is unknown.
Schafiq Nabhani +13 more
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Fetal-derived trophoblast use the apoptotic cytokine tumor necrosis factor-alpha-related apoptosis-inducing ligand to induce smooth muscle cell death. [PDF]
, 2007 Remodeling of the uterine spiral arteries during pregnancy transforms them from high to low resistance vessels that lack vasoconstrictive properties. This process is essential to meet the demand for increased blood flow imposed by the growing fetus. Loss
Aplin, JD +6 more
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Haematologica, 2013 Clinical and genetic heterogeneity renders confirmation or exclusion of autoimmune lymphoproliferative syndrome difficult. To re-evaluate and improve the currently suggested diagnostic approach to patients with suspected FAS mutation, the most frequent ...
Anne Rensing-Ehl +36 more
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FasL Expression in Articular Discs of Human Temporomandibular Joint and Association with Osteoarthrosis [PDF]
, 2013 Background Apoptosis is a programme of cell death which does not induce an inflammatory response. Recent previous research has suggested a correlation between temporomandibular internal derangement and apoptosis.
Alanis, Luciana Reis Azevedo +9 more
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Artificial Cells, Nanomedicine, and Biotechnology, 2019 In this study, sevoflurane (SF) loaded, Fas ligand conjugated reduced graphene oxide (rGO) system is fabricated as a therapeutic agent to target brain ischaemic region. The fluorescence investigation of mice brain denoted that the encapsulated SF in rGOs
Qinjuan Wu, Mingfeng Qin, Kun Zhang
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