Results 191 to 200 of about 287,562 (282)

Installation of dominant-negative mutations in <i>FAS</i> and <i>TGFβR2</i> via base editing in primary T cells. [PDF]

Mol Ther Oncol
Wick BJ, Kluesner MG, Slipek NJ, Skeate JG, Niemeyer EM, Webber BR, Moriarity BS.   +6 more
europepmc   +1 more source

Ventilator‐Induced Lung Injury: Mechanotransduction and Potential Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
Mechanical ventilation (MV) is expected to undergo significant transformative advancements by 2050, with the emergence of personalized ventilation systems that promise to revolutionize respiratory care. However, the risk of ventilator‐induced lung injury (VILI) remains a significant concern at this stage and VILI still exists at that time.
He Ren, Ziqi Shang, Alastair G. Stewart, Ying‐xin Qi, Kai Huang   +4 more
wiley   +1 more source

A Comprehensive Review on Medium- and Long-Chain Fatty Acid-Derived Metabolites: From Energy Sources to Metabolic Signals. [PDF]

Metabolites
Park JB, Cho S, Lee SJ.
europepmc   +1 more source

Estrogen preserves Fas ligand levels by inhibiting microRNA‐181a in bone marrow‐derived mesenchymal stem cells to maintain bone remodeling balance

The FASEB Journal, 2015
B. Shao, L. Liao, Yang Yu, Yi Shuai, X. Su, Huan Jing, Deqin Yang, Yan Jin   +7 more
semanticscholar   +1 more source

Proximal Pulmonary Artery Stiffening as a Biomarker of Cardiopulmonary Aging

Aging Cell, Volume 25, Issue 2, February 2026.
Mouse models revealed age‐associated increased circumferential stiffness of the proximal pulmonary artery that was associated with reorientation of collagen and decreased function of the lung and right ventricle. Age‐related transcriptional changes were indicative of senescence, ECM turnover, TGFβ signaling, and altered intercellular signaling among ...
Ruben De Man, Zhongyu Cai, Pramath Doddaballapur, Nicole Guerrera, Alexandria Regan, Liqin Lin, Erica Schwarz, Aurelien Justet, Nebal S. Abu Hussein, Jack Di Palo, Cristina Cavinato, Micha Sam B. Raredon, Paul M. Heerdt, Inderjit Singh, Xiting Yan, Min‐Jong Kang, Danielle R. Bruns, Patty J. Lee, George Tellides, Jay D. Humphrey, Naftali Kaminski, Abhay B. Ramachandra, Edward P. Manning   +22 more
wiley   +1 more source

Regulation of cell surface expression of Fas (CD95) ligand and susceptibility to Fas (CD95)-mediated apoptosis in activation-induced T cell death involves calcineurin and protein kinase C, respectively [PDF]

, 1999
Réka Tóth, Éva Szegezdi, Gábor M. Molnár, Janet M. Lord, László Fésüs, Zsuzsa Szondy   +5 more
openalex   +1 more source

Can Environmental Enrichment Mitigate Cell Apoptosis in the Central Nervous System Under Adverse Health Conditions? A Systematic Review

Clinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT To summarize the available evidence in the literature regarding the effects of exposure to an enriched environment (EE) on the modulation of apoptotic markers in central tissue of rodents under unfavorable conditions. Searches were conducted in three databases: PubMed/Medline (70 articles), Scopus (65 articles), and EMBASE (128 articles), all ...
Matheus Santos de Sousa Fernandes, Diorginis José Soares Ferreira, Fatma Hilal Yagin, Georgian Badicu, Gabriela Carvalho Jurema Santos, Maria Carolina Santos Guedes, Fabrício Oliveira Souto, Luca Paolo Ardigò   +7 more
wiley   +1 more source

Bridging the gaps: advanced techniques to unlock lipid function in plant reproductive development. [PDF]

Plant Reprod
Guo ZH, Chye ML.
europepmc   +1 more source

Long Non-Coding RNA LINC00324 Exerts Pro-Tumorigenic Effects on Liver Cancer Stem Cells by Up-Regulating Fas Ligand <i>via</i> PU Box Binding Protein

, 2019
Jun Gao, Dai Chao, Xin Yu, Xiangbao Yin, Fan Zhou   +4 more
openalex   +1 more source

Human FASTK preferentially binds single‐stranded and G‐rich RNA

The FEBS Journal, Volume 293, Issue 3, Page 729-748, February 2026.
Although FASTK is known to play a role in mRNA biology, the mechanism through which it recognizes RNA has yet to be unraveled. Here, we used purified human FASTK to characterize its RNA‐binding properties in vitro. We found that FASTK prefers ssRNA oligonucleotides containing guanines with the potential to form G‐quadruplexes and binds robustly to any ...
Daria M. Dawidziak, Dawid A. Dzadz, Mikołaj I. Kuska, Madhuri Kanavalli, Maria M. Klimecka, Matthew Merski, Katarzyna J. Bandyra, Maria W. Górna   +7 more
wiley   +1 more source