Results 201 to 210 of about 107,401 (282)

Clinical and Genetic Landscape of Glioblastoma, IDH‐Wildtype With FGFR Gene Family Alterations

Cancer Science, Volume 117, Issue 5, Page 1455-1468, May 2026.
We analyzed 1076 cases of glioblastoma, IDH‐wildtype (GBM, IDH‐wt) using the C‐CAT genomic database to clarify the clinical and genetic features of FGFR alterations. FGFR::TACC fusions and FGFR1 mutations were identified in distinct subsets and were associated with unique co‐mutation patterns.
Yasuhito Kegoya, Yoshihiro Otani, Ryo Mizuta, Ryosuke Ikemachi, Mako Kamiura, Joji Ishida, Shinichi Toyooka, Daisuke Ennishi, Shuta Tomida, Shota Tanaka   +9 more
wiley   +1 more source

MCP-1/CCR2 axis regulates M2 macrophage polarization and immunosuppression in mycobacterium tuberculosis. [PDF]

Front Immunol
Zhao G, Guo C, Li X, Tan L, Chen X, Tian F, Zhang L, Wang X, Cui J.   +8 more
europepmc   +1 more source

Gain‐of‐function enhancers optimize CAR‐NK cell‐based anti‐cancer immunotherapy

Immunology &Cell Biology, Volume 104, Issue 5, Page 494-498, May‐June 2026.
Schematic overview of the two‐stage screening approach used to identify NK cell fitness genes. (A) CRISPRa mechanism, showing dCas9‐VP64‐mediated upregulation of target genes. (B) Whole‐genome CRISPRa screening in HER2‐CAR‐NK92 cells transduced with a CRISPR sgRNA library and transferred into mice bearing HT29 tumours, followed by tumour collection and
Emma Wong, Fernando Souza‐Fonseca‐Guimaraes   +1 more
wiley   +1 more source

Endothelial cells as targets of immune checkpoint blockade. [PDF]

J Immunother Cancer
Korman AJ, Taylor M, Stephen Hodi F.
europepmc   +1 more source

B Cell Subsets and Atherosclerosis: Updates and Emerging Concepts

Immunological Reviews, Volume 339, Issue 1, May 2026.
ABSTRACT Atherosclerotic cardiovascular disease (ASCVD) is increasingly recognized not just as a lipid‐driven disease, but as a complex interplay between vascular cells and the immune system. Accumulating evidence highlights a central, yet heterogeneous role for B cells in atherogenesis, with distinct subsets displaying opposing roles.
Sophieke Lems, Megan Grace Mazzei, Amanda C. Foks, Coleen A. McNamara   +3 more
wiley   +1 more source

Inhibition of death-ligand-induced apoptosis in Epstein-Barr virus-encoded small RNAs-expressing human T-cell line. [PDF]

Infect Agent Cancer
Matsumoto Y, Tateishi A, Kanno H.
europepmc   +1 more source

Exosomal Non‐Coding RNAs in Gastrointestinal Cancer Drug Resistance: A Systematic Review of Emerging Mechanisms and Clinical Implications

Journal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT Gastrointestinal (GI) tumours are one of the most prevalent cancers globally. Even with normal GI function, individuals may develop neoplasms, highlighting the need to better understand the underlying causes of tumorigenesis. The emergence of tumour drug resistance represents the main reason for the failure of drug treatment; thus, it is ...
Mohsen Sharif‐zak, Zahra Sadeghloo, Fateme Binayi, Stefania Nobili, Sara Ashtari, Amir Sadeghi, Nayeralsadat Fatemi   +6 more
wiley   +1 more source

Serum Levels of Soluble Forms of Fas and FasL in Patients with Pancreatic and Papilla of Vater Adenocarcinomas. [PDF]

Cancers (Basel)
Anagnostoulis S, Bolanaki H, Asimakopoulos B, Ouroumidis D, Koutini M, Patris S, Tzimagiorgis I, Karayiannakis AJ.   +7 more
europepmc   +1 more source

Antibiofilm and antibacterial effects of <i>Nigella sativa</i> extract against <i>Streptococcus mutans</i> predicting the role of fatty acids composition: <i>in vitro</i>, CLSM and <i>in</i> <i>silico</i> studies. [PDF]

Biomater Investig Dent
ELsayed S, El-Adl K, Sadony DM, Gad HA, Yousef A, Radwan AA.   +5 more
europepmc   +1 more source

Swainsonine Protects Human Thyrocytes from Fas-Induced Apoptosis: In vitro Study on Nthy-Ori 3-1 Cell Line. [PDF]

J Inflamm Res
Trzos S, Opydo M, Bochenek M, Link-Lenczowski P, Pocheć E.   +4 more
europepmc   +1 more source