Results 181 to 190 of about 105,192 (298)

Radiotherapy and Immunotherapy In Hepatocellular Carcinoma: Priming the Tumor Immune Microenvironment From Bench To Bedside

Precision Radiation Oncology, EarlyView.
The dual immunomodulatory network of radiotherapy in hepatocellular carcinoma. Radiotherapy initiates its effects by inducing immunogenic cell death and DNA double‐strand breaks. Immune Activation: Cytosolic DNA from damaged cells activates the cGAS‐STING pathway, triggering IRF3/NF‐κB‐mediated type I interferon production. This enhances dendritic cell
Zhigang Fu, Yang Zhang, Zuomin Wang, Zongjuan Li, Shisuo Du   +4 more
wiley   +1 more source

Decoding TNF receptor superfamily control of CD4⁺Foxp3⁺ Regulatory T cell-mediated tolerance: implications for the treatment of graft‑versus‑host disease. [PDF]

Cell Commun Signal
Chou CK, Wang X, Yu R, Xu H, Chen Y, Yang Y, Chen Z, Li C, He T, Chen X.   +9 more
europepmc   +1 more source

The continuing significance of chiral agrochemicals

Pest Management Science, Volume 81, Issue 4, Page 1697-1716, April 2025.
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley   +1 more source

Docetaxel enhances Vβ-directed T-cell activation and antitumor immunity mediated by a bifunctional TCR agonist in breast and prostate cancer models. [PDF]

Front Immunol
Lee JK, Fabian KP, Santiago-Sanchez GS, Rosato F, Padget MR, Lee C, Su Z, Moisan J, Katragadda M, Schlom J, Gulley JL, Bayliffe A, Hodge JW.   +12 more
europepmc   +1 more source

Three‐Year Propagation Experiment at Ku‐, Ka‐, and Q‐Band in French West Indies

International Journal of Satellite Communications and Networking, EarlyView.
ABSTRACT From January 2021 to December 2023, the Office National d'Etudes et de Recherches Aérospatiales (ONERA) and the Centre National d'Etudes Spatiales (CNES) conducted a three‐year Earth‐space propagation measurement campaign in Guadeloupe. The experiment used beacon receivers deployed in Pointe‐à‐Pitre airport to record signals at 11.2, 19.7, and
Jean‐Pascal Monvoisin, Laurent Castanet, Laurent Féral, Xavier Boulanger   +3 more
wiley   +1 more source

Effects of Omega-3 Fatty Acids on High-Fat Diet-Induced Obesity: A Systematic Review of Rodent Studies. [PDF]

Nutr Rev
Saban Güler M, Yıldıran H.
europepmc   +1 more source

Genetic disruption of oncogenic Kras sensitizes lung cancer cells to Fas receptor-mediated apoptosis. [PDF]

Proc Natl Acad Sci U S A, 2017
Mou H, Moore J, Malonia SK, Li Y, Ozata DM, Hough S, Song CQ, Smith JL, Fischer A, Weng Z, Green MR, Xue W.   +11 more
europepmc   +1 more source

Self‐Assembling Cationic Lipopeptides for the Construction of Functional Vesicular Gene‐Delivery Systems

Small, EarlyView.
Cationic lipopeptides self‐assemble into stable, cell‐like vesicles that merge peptide programmability with lipid self‐organization. These biocompatible compartments efficiently sequester and deliver nucleic acids, enabling high transfection efficiency with low‐toxicity in both HEK293T cells and mesenchymal stem cells (MSCs).
Federica A. Souto‐Trinei, Alba Ramil‐Bouzas, Paco Fernández‐Trillo, Ana Rey‐Rico, Roberto J. Brea   +4 more
wiley   +1 more source

Cardiac Lipid Metabolism: Cells, Metabolites, and Rhythms. [PDF]

Circ Res
Goldberg IJ, Young ME, Schulze PC, Drosatos K.   +3 more
europepmc   +1 more source

Leverage Points for Meaningful Participation: A 5‐Point Framework From a Rural South African Landscape

Systems Research and Behavioral Science, EarlyView.
ABSTRACT Alternative forms of natural resource management are required. Participation of local actors is necessary but not sufficient, for moving away from the conventional top‐down approaches. This paper develops a 5‐point framework for enabling meaningful participation in rural landscape governance.
Anthony S. Fry, Jai K. Clifford‐Holmes, Carolyn G. Palmer   +2 more
wiley   +1 more source