Results 31 to 40 of about 87,501 (308)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Association of junk food consumption with overweight-obesity among preclinical medical students of Shahid Beheshti University of Medical Sciences

Social Determinants of Health, 2019
Background: The consumption of high energy and low nutritional content foods, which are known as junk foods, is considered as one of the main causes of obesity particularly in adolescents.
Mohammad Masih Mansouri-Tehrani, Seyedreza Hashemi-rad, Tiam Hajiha, Seyedalisina Mousavian, Arezoo Rezazadeh   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Factors Affecting Underweight and Obesity Among Elementary School Children in South Korea

Asian Nursing Research, 2015
Purpose: The purpose of the study was to determine factors associated with underweight and obesity in elementary school children in Korea. Methods: Study participants included 4,895 children attending 59 elementary schools across Korea.
GyuYoung Lee, RN, PhD, Ok Kyung Ham, PhD, MPH, MCHES   +1 more
doaj   +1 more source

Determining intention, fast food consumption and their related factors among university students by using a behavior change theory

BMC Public Health, 2022
Background Today, with the advancement of science, technology and industry, people’s lifestyles such as the pattern of people’s food, have changed from traditional foods to fast foods.
Alireza Didarloo, Surur Khalili, Ahmad Ali Aghapour, Fatemeh Moghaddam-Tabrizi, Seyed Mortaza Mousavi   +4 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Associations between dietary patterns and metabolic syndrome in adolescents

Salud Pública de México, 2019
Objective. Evaluate association of dietary patterns with metabolic syndrome (MetS) and metabolic markers. Mate­rials and methods. 654 adolescents from Guadalajara, Jalisco, participated in a cross-sectional study.
Guadalupe Ramírez-López, Mario Flores-Aldana, Jorge Salmerón   +2 more
doaj   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source