Results 91 to 100 of about 798,983 (300)

Onset of Fast Magnetic Reconnection in Partially Ionized Gases

, 2011
We consider quasi-stationary two-dimensional magnetic reconnection in a partially ionized incompressible plasma. We find that when the plasma is weakly ionized and the collisions between the ions and the neutral particles are significant, the transition ...
Balbus, Braginskii, Cowley, De Pontieu, Drake, Ellen G. Zweibel, Heitsch, Hillier, Kulsrud, Lazarian, Leonid M. Malyshkin, Malyshkin, McKee, Sturrock, Sweet   +14 more
core   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Collisional kinetics of non-uniform electric field, low-pressure, direct-current discharges in H$_{2}$

, 2010
A model of the collisional kinetics of energetic hydrogen atoms, molecules, and ions in pure H$_2$ discharges is used to predict H$_\alpha$ emission profiles and spatial distributions of emission from the cathode regions of low-pressure, weakly-ionized ...
A V Phelps, Babkina T, Barbeau C, Brehm B, Dexter A C, Donkó Z, Durup J, Eckstein W, Emmert G A, Fournier P, Francis G, Geddes J, Helm H, Hey J D, Hunter H T Kirkpatrick M I Alvarez I Cisneros C Phaneuf R A, Jelenković B M, Jelenković B M, Kirichenko V I, Kirichenko V I, Konjević N, Lavrov B P, Lavrov B P, Lavrov B P, Lavrov B P, Louriero J, Petrović Z Lj Phelps A V, Petrović Z Stojanović V Popović L C Dimitrijević M S, Phelps A V, Phelps A V, Prelec K, Rao M V V S Van Brunt R J Olthoff J K Rescigno p T N, Thomas E W, von Engle A, Ŝimko T Bretagne J Gousset G Bordage M C Gleizes A   +33 more
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Orbit tomography in constants-of-motion phase-space

Nuclear Fusion
Tomographic reconstructions of a 3D fast-ion constants-of-motion phase-space distribution function are computed by inverting synthetic signals based on projected velocities of the fast ions along the diagnostic lines of sight.
M. Rud, D. Moseev, F. Jaulmes, K. Bogar, Y. Dong, P.C. Hansen, J. Eriksson, H. Järleblad, M. Nocente, G. Prechel, B.C.G. Reman, B.S. Schmidt, A. Snicker, L. Stagner, A. Valentini, M. Salewski   +15 more
doaj   +1 more source

Ion acceleration mechanism in mega-ampere gas-puff z-pinches

New Journal of Physics, 2018
Acceleration of high energy ions was observed in z-pinches and dense plasma foci as early as the 1950s. Even though many theories have been suggested, the ion acceleration mechanism remains a source of controversy. Recently, the experiments on the GIT-12
D Klir, A V Shishlov, V A Kokshenev, P Kubes, K Rezac, R K Cherdizov, J Cikhardt, B Cikhardtova, G N Dudkin, F I Fursov, T Hyhlik, J Kaufman, B M Kovalchuk, J Krasa, J Kravarik, N E Kurmaev, A Yu Labetsky, V Munzar, H Orcikova, V N Padalko, N A Ratakhin, O Sila, J Stodulka, K Turek, V A Varlachev, R Wagner   +25 more
doaj   +1 more source

ASCOT: solving the kinetic equation of minority particle species in tokamak plasmas

, 2013
A comprehensive description of methods, suitable for solving the kinetic equation for fast ions and impurity species in tokamak plasmas using Monte Carlo approach, is presented.
Asunta, Otto, Hirvijoki, Eero, Koskela, Tuomas, Kurki-Suonio, Taina, Miettunen, Juho, Sipilä, Seppo, Snicker, Antti, Äkäslompolo, Simppa   +7 more
core   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Influence of ion cyclotron range of frequencies heating on neutron emission rate in HL-3 tokamak

He jishu
BackgroundIon cyclotron range of frequencies (ICRF) heating is one of the most widely used auxiliary heating methods in tokamaks. The HL-3 tokamak plans to equip a 6 MW ICRF heating system to conduct discharge experiments of high-performance plasma ...
YANG Guanming, HAO Guangzhou, LU Lingfeng, DONG Guanqi, HAO Baolong, WANG Shuo   +5 more
doaj   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source