Results 131 to 140 of about 8,467 (226)

A General Strategy for the Synthesis of Jerangolids Enabled by π‐allyl Stille Coupling

open access: yesChemistry – A European Journal, Volume 32, Issue 23, 16 June 2026.
A general strategy for the synthesis of jerangolids is established, featuring a late‐stage π‐allyl Stille coupling of two advanced, highly customizable building blocks to form the skipped diene core. The approach provides access to all naturally occurring jerangolids, including jerangolid H, whose configuration is confirmed by NMR analysis.
Janick Schug   +2 more
wiley   +1 more source

A Multimodal Analysis of Serum and Tear Crystallization Patterns in Patients with Obesity. [PDF]

open access: yesJ Clin Med
Ganea CV   +8 more
europepmc   +1 more source

Borates in Biomedicine: A Retrospective Analysis

open access: yesChemMedChem, Volume 21, Issue 11, 15 June 2026.
The graphical abstract displays the molecular structure of boric acid, an hormetic substance with pleiotropic bioactivity. Complementing previous studies describing the use of organoboron compounds as potent therapeutics for use in anticancer, antimicrobial, antiparasitic, and related other pharmaceutical uses, this study focuses on the emerging ...
Mario Pagliaro   +3 more
wiley   +1 more source

Bayesian Optimization of Solvent‐Free Thermal Amidation via Reactive Extrusion

open access: yesChemistry – A European Journal, Volume 32, Issue 22, 9 June 2026.
Thermal amidation between a carboxylic acid and an amine was successfully conducted in an extruder in the absence of solvent, coupling agent, or catalyst, relying on an adapted Bayesian Optimization protocol. Active pharmaceutical ingredient moclobemide was synthesized on a larger scale, achieving excellent yield and low Process Mass Intensity (PMI ...
Matthieu Lavayssiere   +2 more
wiley   +1 more source

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