Results 71 to 80 of about 5,872,533 (292)

Fragmented Fat Transfer for Massive Weight Loss Gluteal Contouring

open access: yesPlastic & Reconstructive Surgery, 2022
Summary: A recently introduced novel fragmentation technique has made it possible to convert fat tissue from apronectomy into large-scale viable lipograft, providing a glimpse of an alternative to traditional liposuction and its harvesting limitations.
Mendes, Flavio Henrique, Viterbo, Fausto
openaire   +4 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Investigating weight loss resistance across the menopausal transition: a preliminary quantitative survey of resistance-trained women

open access: yesJournal of the International Society of Sports Nutrition
Background Many women enter midlife unaware of the physiological and hormonal changes associated with the menopause transition. This period is commonly characterized by increased fat mass and decreased lean body mass.
Anna Oelmann   +10 more
doaj   +1 more source

The Effect of Low-Fat and Low-Carbohydrate Diets on Weight Loss and Lipid Levels: A Systematic Review and Meta-Analysis

open access: yesNutrients, 2020
Background: The rise in obesity has emphasised a focus on lifestyle and dietary habits. We aimed to address the debate between low-carbohydrate and low-fat diets and compare their effects on body weight, low-density lipoprotein cholesterol (LDL), high ...
S. Chawla   +4 more
semanticscholar   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Relative effects of weight loss and dietary fat modification on serum lipid levels in the dietary treatment of obesity.

open access: yesJournal of Lipid Research, 1993
The independent effects of weight loss and dietary fat modification on serum lipids were investigated in two groups of healthy moderately obese men and women.
R Leenen   +5 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Prevention of Loss of Body Fat by Cortisone

open access: yesExperimental Biology and Medicine, 1950
Summary and conclusionsAdrenalectomized rats, partially starved for 5 days, lost approximately 4 times as much adipose tissue as similar animals injected with 2 mg of compound E daily and twice as much as sham operated controls. The daily injection of 2 mg of DCA did not prevent the excessive loss of fat in adrenalectomized animals.
H C, STOERK, C C, PORTER
openaire   +2 more sources

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

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