Results 71 to 80 of about 1,305,621 (307)

Effect of body composition methodology on heritability estimation of body fatness [PDF]

, 2012
Heritability estimates of human body fatness vary widely and the contribution of body composition methodology to this variability is unknown. The effect of body composition methodology on estimations of genetic and environmental contributions to body ...
Bouchard, Thomas J., Das, Sai Krupa, Dawson-Hughes, Bess, Elder, Sonya J., Fuss, Paul J., Greenberg, Andrew S., Heymsfield, Steven B., McCrory, Megan A., Neale, Michael C., Pittas, Anastassios G., Roberts, Susan B., Saltzman, Edward   +11 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Fat and fat-free mass as important determinants of body composition assessment in relation to sarcopenic obesity

Roczniki Panstwowego Zakladu Higieny, 2023
Background. Fat and fat-free/muscle mass and their ratio reflecting the possible presence of obesity or sarcopenic obesity are important in assessing body composition. Objective.
Martina Gažarová, Maroš Bihari, Jaroslav Šoltís   +2 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

The impact of body composition and fat distribution on blood pressure in young and middle-aged adults

Frontiers in Nutrition, 2022
BackgroundThe relative contributions of each component of body composition to blood pressure (BP) remain unclear.ObjectiveWe aimed to comprehensively investigate the impact of body composition and fat distribution on BP and quantify their relative ...
Song Zhao, Jiamin Tang, Yifan Zhao, Chong Xu, Yawei Xu, Shikai Yu, Yi Zhang   +6 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Ratio of fat-free mass to fat mass is associated with physical performance in patients with type 2 diabetes mellitus

Frontiers in Endocrinology
BackgroundThe ratio of fat-free mass (FFM) to fat mass (FM) is a key indicator of body composition. Evidence suggests that the FFM/FM ratio is more reliable than body mass index in predicting functional outcomes in older adults with prefrailty ...
Jui-Hsiang Sung, Fu-Shun Ko, Tsung-Hui Wu, Tsung-Hui Wu, Shiow-Chwen Tsai, Chii-Min Hwu, Chii-Min Hwu, Guan-Yu Su, Guan-Yu Su   +8 more
doaj   +1 more source

Trunk fat and leg fat in relation to free triiodothyronine in euthyroid postmenopausal women

Endocrine Connections, 2019
Background: A high level of free triiodothyronine (FT3) within the referen ce range may be a potential metabolic risk marker. However, the relationship between different fat depots and FT3 has remained unclear.
Xiaomin Nie, Yiting Xu, Xiaojing Ma, Yun Shen, Yufei Wang, Yuqian Bao   +5 more
doaj   +1 more source

Dietary Fiber Intake Is Related to Skeletal Muscle Mass, Body Fat Mass, and Muscle-to-Fat Ratio Among People With Type 2 Diabetes: A Cross-Sectional Study

Frontiers in Nutrition, 2022
ObjectivesTo investigate the relationship between dietary fiber intake and skeletal muscle mass, body fat mass, and muscle-to-fat ratio (MFR) among men and women with type 2 diabetes (T2D).MethodsThis cross-sectional study involved 260 men and 200 women ...
Fuyuko Takahashi, Yoshitaka Hashimoto, Ayumi Kaji, Ryosuke Sakai, Yuka Kawate, Takuro Okamura, Hiroshi Okada, Noriyuki Kitagawa, Noriyuki Kitagawa, Naoko Nakanishi, Saori Majima, Takafumi Osaka, Takafumi Senmaru, Emi Ushigome, Mai Asano, Masahide Hamaguchi, Masahiro Yamazaki, Michiaki Fukui   +17 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source