Results 221 to 230 of about 188,463 (294)

Evaluating the Feasibility of Using <i>Salicornia herbacea</i> Powder as a Salt Substitute in Sausage Production. [PDF]

Food Sci Anim Resour
Jin SK, Cheng H, Kim GD.
europepmc   +1 more source

Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3

Advanced Science, EarlyView.
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang, Linghua Zeng, Kunkun Zou, Keying Lin, Fangting Yao, Jinglun Song, Shumeng Zhang, Hanshu Feng, Zhichao Yang, Chunlei Wang, Hongtao Diao, Xue Kong, Tengfei Pan, Joonki Kim, Tianqi Duo, Linqiang Li, Yu Bian   +16 more
wiley   +1 more source

Mushroom: an emerging source for next generation meat analogues. [PDF]

Front Nutr
Panda J, Nath PC, Mishra AK, Rustagi S, Nayak D, Blundell R, Mohanta YK.   +6 more
europepmc   +1 more source

p16Ink4a‐Positive Hepatocytes Drive Liver Fibrosis Through Activation of LIFR Family Pathway

Advanced Science, EarlyView.
This study found that, following the long‐term CCl4 treatment, p16high hepatocytes appeared in zone 3, spatially co‐localizing with fibrotic areas. A specific cluster of p16high hepatocytes upregulated CTF1/LIF expression which induced HSC activation and further liver fibrosis, as revealed by single cell transcriptomic analysis.
Koji Nishikawa, Teh‐Wei Wang, Satoshi Kawakami, Shota Tanimoto, Kiyoshi Yamaguchi, Taketomo Kido, Masamichi Kimura, Tsunekazu Hishima, Yuki T. Okamura, Satotaka Omori, Takumi Iritani, Toshikaze Chiba, Takehiro Jimbo, Michio Katano, Kansuporn Kamataki, Ryoichi Yokoyama, Eigo Shimizu, Kiminori Kimura, Satoshi Yamzaki, Seiya Imoto, Yoichi Furukawa, Atsushi Miyajima, Yoshikazu Johmura, Makoto Nakanishi   +23 more
wiley   +1 more source

Editorial: Brown and beige adipocytes: from molecular mechanisms to therapeutic potentials. [PDF]

Front Endocrinol (Lausanne)
Li X, Islam S, Du M.
europepmc   +1 more source

Microenvironment Self‐Adaptive Nanoarmor to Address Adhesion‐ and Colonization‐Related Obstacles in Impaired Intestine Promote Bacteriotherapy Against Parkinson's Disease

Advanced Science, EarlyView.
A microenvironment self‐adaptive nanoarmor is developed to effectively address the adhesion‐ and colonization‐related challenges posed by multiple physiological and pathological characteristics in the intestine. L. plantarum@MPN@CS showed significant therapeutic potential in treating Parkinson's disease (PD), a model for extraintestinal disorders, as ...
Limeng Zhu, Yuyu Wu, Yingjie Chen, Xiyi Chen, Xingjie Zan, Yanlong Liu, Wujun Geng   +6 more
wiley   +1 more source

Subchondral Phosphate Injection During Hip Arthroscopy Safely Treats Acetabular Bone Marrow Lesions in Early Osteoarthritis. [PDF]

J Clin Med
Minelli M, Di Matteo B, Longobardi V, D'Addona A, Rosolani M, Pitronaci S, Kon E, Della Rocca F.   +7 more
europepmc   +1 more source

Legumes: Your Ally in Cardiovascular Wellness. [PDF]

Am J Lifestyle Med
Hanus A.
europepmc   +1 more source

Ecchordosis physaliphora presenting with cerebrospinal fluid leak and meningitis: illustrative case. [PDF]

J Neurosurg Case Lessons
Balasubramanian K, Zuccato JA, El Rassi E, Dunn IF.   +3 more
europepmc   +1 more source

Construction of pomelo peel essential oil pickering emulsion and its impact on the freeze-thaw stability of surimi gel. [PDF]

Open Life Sci
Song H, Zhao L, Zhang H, Tian B.
europepmc   +1 more source