Results 81 to 90 of about 389,852 (268)

Cpt1a Drives primed-to-naïve pluripotency transition through lipid remodeling

Communications Biology
Metabolism has been implicated in cell fate determination, particularly through epigenetic modifications. Similarly, lipid remodeling also plays a role in regulating cell fate.
Zhaoyi Ma, Xingnan Huang, Junqi Kuang, Qiannan Wang, Yue Qin, Tao Huang, Zechuan Liang, Wei Li, Yu Fu, Pengli Li, Yixin Fan, Ziwei Zhai, Xiaomin Wang, Jin Ming, Chengchen Zhao, Bo Wang, Duanqing Pei   +16 more
doaj   +1 more source

Toward Fast Proton Shuttling in Acidic Oxygen Evolution Reaction

Advanced Functional Materials, EarlyView.
This review establishes proton transfer dynamics as a descriptor governing acidic OER activity, moving beyond the kinetic constraints derived from the proton coupled electron transfer. We discuss how deprotonation governs classical mechanisms, including adsorbate evolution mechanism (AEM), lattice oxygen mechanism (LOM) and oxide path mechanism (OPM ...
Ashish Gaur, Jaeyeong Kim, Sungwook Mhin, HyukSu Han   +3 more
wiley   +1 more source

Proteomic profiling of UV damage repair patches uncovers histone chaperones with central functions in chromatin repair

Nature Communications
DNA damage compromises not only genome stability but also chromatin integrity, which plays a central role in controlling cell identity. Chromatin repair entails the deposition of new histones at sites of DNA damage.
Alexandre Plessier, Audrey Chansard, Eliane Petit, Julia Novion Ducassou, Yohann Couté, Sophie E. Polo   +5 more
doaj   +1 more source

Steering Oxygen Activation Pathways via Redox Dual‐Defects in 2D Hydrated WO3 for High‐Yield Singlet Oxygen Evolution

Advanced Functional Materials, EarlyView.
Redox dual‐defects (Cs substitution and O vacancies) in 2D hydrated WO3 steer O2 activation toward selective singlet oxygen evolution. WO‐CO achieves 8.6–15.8 times higher 1O2 production than single‐defect or pristine catalysts, enabling efficient pollutant mineralization via a pathway‐selective photocatalytic mechanism.
Sheng‐Qi Guo, Mingqi Xiao, Fangyuan Zhang, Hui Li, Yuli Jia, Zhenfang Zhang, Liqun Ye, Bo Yang, Tianyi Ma   +8 more
wiley   +1 more source

The Fate of the Claudicator [PDF]

BMJ, 1960
A, SINGER, C, ROB
openaire   +2 more sources

Functional Blood‐Brain Barrier Crossing by Biomimetic M13 Phage Vectors for Targeted Neuronal Delivery

Advanced Healthcare Materials, EarlyView.
This study investigates the M13 bacteriophage as a biomimetic nanovector capable of crossing in vitro models of the blood–brain barrier. By exploiting peculiar transcellular pathways, M13 avoids lysosomal degradation and preserves its structural integrity and functionality.
Silvia Vercellino, Lucia Pappagallo, Francesca De Chirico, Luca Boselli, Hazem Ahmed, Luca Spagnoletti, Giovanni Pittaluga, Paolo Emidio Costantini, Matteo Calvaresi, Pier Paolo Pompa, Alberto Danielli, Fabio Benfenati, Valentina Castagnola   +12 more
wiley   +1 more source

Microgel‐Based 3D Bioprinting: A Convergent Strategy Integrating Material Design, Jamming Dynamics, and Biological Function

Advanced Healthcare Materials, EarlyView.
Microgel‐based 3D printed constructs represent a compelling and versatile innovation for engineering architecturally complex, dynamically remodelable, and biocompatible structures with high structural fidelity and bioactivity. By integrating material design, biofabrication, and biological function, these systems enable the development of adaptive ...
Elena Ghighină, Andreea Ioana Dinu, Jana Ghițman   +2 more
wiley   +1 more source

Structure of human PIEZO1 and its slow-inactivating channelopathy mutants

eLife
PIEZO channels transmit mechanical force signals to cells, allowing them to make critical decisions during development and in pathophysiological conditions.
Yuanyue Shan, Xinyi Guo, Mengmeng Zhang, Meiyu Chen, Ying Li, Mingfeng Zhang, Duanqing Pei   +6 more
doaj   +1 more source

The Fate of the Scientist, the Fate of Science

MGIMO Review of International Relations, 2012
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openaire   +3 more sources

Immunoinflammatory Mechanisms and Biocompatibility of Bioactive Dental Biomaterials: From Fundamental Insights to Clinical Translation

Advanced Healthcare Materials, EarlyView.
Surface‐host dialogue at the implant interface governs biological fate and osseointegration. Surface physicochemical properties of titanium (Ti) dental implants, including microgrooves, nanopatterns, nanotopography, roughness, and wettability, modulate the initial adsorption of proteins and the formation of a dynamic biointerface.
Daniela Moreira Cunha, Amanda Paino Santana, Marta Maria Alves Pereira, Mariana Martins Guerreiro, Jose Mauro Granjeiro, Jamil Awad Shibli, Jeroen J. J. P. van den Beucken, Anton Sculean, Rafael Scaf de Molon, Erica Dorigatti de Avila   +9 more
wiley   +1 more source