Results 41 to 50 of about 6,167,446 (362)

The role of fibroblast growth factors in cell and cancer metabolism

open access: yesFEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

Blood omega-3 fatty acids and coronary artery stenosis: a postmortem study

open access: yesLipids in Health and Disease
The role of omega-3 fatty acids in the atherosclerotic process remains unclear. Early studies demonstrated a profound anti-atherogenic effect of cod liver oil in a pig model, and autopsy reports from Alaska Natives consuming omega-3 rich diets have ...
Brad Randall   +3 more
doaj   +1 more source

Utilization of free fatty acids complexed to human plasma lipoproteins by mammalian cell suspensions

open access: yesJournal of Lipid Research, 1971
The purpose of this study was to determine whether lipoprotein-bound free fatty acid could be utilized by isolated mammalian cells. Ehrlich ascites tumor cells were incubated in vitro with radioactive free fatty acids that were bound to human plasma ...
ARTHUR A. SPECTOR, JANICE M. SOBOROFF
doaj   +1 more source

Dynamic accumulation of fatty acids in duck (Anas platyrhynchos) breast muscle and its correlations with gene expression

open access: yesBMC Genomics, 2020
Background Fatty acid composition contributes greatly to the quality and nutritional value of meat. However, the molecular regulatory mechanisms underlying fatty acid accumulation in poultry have not yet been cleared.
Wenlei Fan   +8 more
doaj   +1 more source

Trans-Fatty Acids [PDF]

open access: yes, 2016
Not all fats are suitable for high frying at temperatures of 130–180 °C. Water in fats, like in butter, evaporates at 100 °C and then starts to spatter. Excipients from the pulp of cold-pressed oils can become altered and develop an unpleasant odor or taste when heated above 150 °C.
openaire   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Biosynthetic mechanism of very long chain polyunsaturated fatty acids in Thraustochytrium sp. 26185[S]

open access: yesJournal of Lipid Research, 2016
Thraustochytrium, a unicellular marine protist, has been used as a commercial source of very long chain PUFAs (VLCPUFAs) such as DHA (22:6n-3). Our recent work indicates coexistence of a Δ4-desaturation-dependent pathway (aerobic) and a polyketide ...
Dauenpen Meesapyodsuk, Xiao Qiu
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Sexually dimorphic brain fatty acid composition in low and high fat diet-fed mice

open access: yesMolecular Metabolism, 2016
Objective: In this study, we analyzed the fatty acid profile of brains and plasma from male and female mice fed chow or a western-style high fat diet (WD) for 16 weeks to determine if males and females process fatty acids differently.
Carlos Rodriguez-Navas   +2 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

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