Results 51 to 60 of about 322,484 (301)

Comparative Analysis of Muscle Transcriptome between Pig Genotypes Identifies Genes and Regulatory Mechanisms Associated to Growth, Fatness and Metabolism. [PDF]

, 2015
Iberian ham production includes both purebred (IB) and Duroc-crossbred (IBxDU) Iberian pigs, which show important differences in meat quality and production traits, such as muscle growth and fatness.
Ayuso, Miriam, Barragán, Carmen, Benítez, Rita, Cánovas, Ángela, Fernández, Almudena, Fernández, Ana Isabel, González-Bulnes, Antonio, Isabel, Beatriz, López-Bote, Clemente, Medrano, Juan F, Núñez, Yolanda, Ovilo, Cristina, Rey, Ana Isabel   +12 more
core   +4 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Leveraging a Fluorescent Fatty Acid Probe to Discover Cell-Permeable Inhibitors of Plasmodium falciparum Glycerolipid Biosynthesis

Microbiology Spectrum, 2022
A sensitive and quantitative fluorescence-based approach is presented for characterizing fatty acid acquisition and lipid biosynthesis by asexually replicating, intraerythrocytic Plasmodium falciparum.
Christie Dapper, Jiapeng Liu, Michael Klemba   +2 more
doaj   +1 more source

Gating mechanism of elongating β-ketoacyl-ACP synthases. [PDF]

, 2020
Carbon-carbon bond forming reactions are essential transformations in natural product biosynthesis. During de novo fatty acid and polyketide biosynthesis, β-ketoacyl-acyl carrier protein (ACP) synthases (KS), catalyze this process via a decarboxylative ...
Bartholow, Thomas G, Burkart, Michael D, Chen, Aochiu, Davis, Tony D, Kim, Woojoo E, La Clair, James J, McCammon, J Andrew, Mindrebo, Jeffrey T, Noel, Joseph P, Patel, Ashay   +9 more
core  

ZZE-Configuration of chromophore ß-153 in C-phycocyanin from Mastigocladus laminosus [PDF]

, 1987
The photochemistry of C-phycocyanin has been studied after denaturation in the dark. It shows an irreversible reaction which has characteristics of a Ζ,Ζ,Ε- to Z,Z,Z-isomerization of dihydrobilins. Its amplitude depends on the reaction conditions, with
Bode, W., Fischer, R., Huber, R., Rüdiger, W., Scheer, Hugo, Schirmer, T., Schmidt, G., Siebzehnrübl, S.   +7 more
core   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Transcriptome and metabolome analysis reveals the effects of fatty acid degradation on flavonoid biosynthesis in apple

Fruit Research
In flavonoid biosynthesis, the phenylpropanoid branch has received increasing attention, but little attention has been paid to the fatty acid β-oxidation branch involved in providing the necessary malonyl-Coenzyme A (CoA) moieties of flavonoids. Here, we
Haoliang Wan, Tongtong Wang, Zhongyu Wang, Yuanming Zhou, Mengyao Yang, Kangni Yang, Jiyun Nie   +6 more
doaj   +1 more source

Transcriptome responses of Lactobacillus acetotolerans F28 to a short and long term ethanol stress

Scientific Reports, 2017
Lactobacillus acetotolerans is a major microbe contributing to the Chinese liquor fermentation with unknown function. It can be grown well in a high concentration of ethanol. RNA sequencing (RNA-seq) was performed on L.
Xiaopan Yang, Kunling Teng, Jie Zhang, Fangfang Wang, Tong Zhang, Guomin Ai, Peijie Han, Fengyan Bai, Jin Zhong   +8 more
doaj   +1 more source

Metabolic perturbations associated with the consumption of a ketogenic medium-chain TAG diet in dogs with idiopathic epilepsy [PDF]

, 2018
Consumption of diets containing medium-chain TAG (MCT) has been shown to confer neuroprotective effects. We aim to identify the global metabolic perturbations associated with consumption of a ketogenic diet (medium-chain TAG diet (MCTD)) in dogs with ...
Benjamini, Brian Zanghi, Elizabeth J. Want, Geyelin, Hill, Holger A. Volk, Isaac, Law, Patterson, Tsz Hong Law, Yuanlong Pan   +10 more
core   +2 more sources

Mitochondrial Stimulation of Fatty Acid Biosynthesis

Journal of Biological Chemistry, 1964
The original observation of Brady and Gurin (1) and Dituri and Gurin (2) that citrate stimulated fatty acid biosynthesis has been confirmed and extended by many other workers (3-8). Brady, Mamoon, and Stadtman (4) showed that the stimulation of fatty acid synthesis by citrate was due in part to the generation of reduced nicotinamide adenine ...
A M, BHADURI, P A, SRERE
openaire   +2 more sources