Results 1 to 10 of about 806,764 (304)

Metabolomics of dietary fatty acid restriction in patients with phenylketonuria. [PDF]

PLoS ONE, 2012
BACKGROUND: Patients with phenylketonuria (PKU) have to follow a lifelong phenylalanine restricted diet. This type of diet markedly reduces the intake of saturated and unsaturated fatty acids especially long chain polyunsaturated fatty acids (LC-PUFA ...
Ulrike Mütze, Skadi Beblo, Linda Kortz, Claudia Matthies, Berthold Koletzko, Mathias Bruegel, Carmen Rohde, Joachim Thiery, Wieland Kiess, Uta Ceglarek   +9 more
doaj   +6 more sources

Identifying biomarkers of hepatic fatty acid metabolism disorder in sevoflurane-induced brain developmental injury by bioinformatics analysis [PDF]

Frontiers in Molecular Neuroscience
IntroductionExposure to sevoflurane in neonatal rats disrupts energy metabolism during brain development, which is associated with anesthetic-induced neurodevelopmental toxicity.
Haozheng Yuan, Yuying Lv, Pei Fan, Pengyu Jia, Kui Wang, Kailing Hu, Haodong Sun, Xinlin Chen, Pengbo Zhang   +8 more
doaj   +2 more sources

Bifidobacterium breve with α-Linolenic Acid and Linoleic Acid Alters Fatty Acid Metabolism in the Maternal Separation Model of Irritable Bowel Syndrome [PDF]

, 2012
peer-reviewedThe aim of this study was to compare the impact of dietary supplementation with a Bifidobacterium breve strain together with linoleic acid & α-linolenic acid, for 7 weeks, on colonic sensitivity and fatty acid metabolism in rats.
Barrett, Eoin, Cryan, John F., Dinan, Timothy G., Fitzgerald, Gerald F, Fitzgerald, Patrick, Kiely, Barry, O'Toole, Paul W., Quigley, Eamonn M., Ross, R Paul, Shanahan, Fergus, STANTON, CATHERINE   +10 more
core   +13 more sources

Fatty Acid Metabolism Reprogramming in Advanced Prostate Cancer

Metabolites, 2021
Prostate cancer (PCa) is a carcinoma in which fatty acids are abundant. Fatty acid metabolism is rewired during PCa development. Although PCa can be treated with hormone therapy, after prolonged treatment, castration-resistant prostate cancer can develop
Huan Xu, Yanbo Chen, Meng Gu, Chong Liu, Qi Chen, Ming Zhan, Zhong Wang   +6 more
doaj   +1 more source

Advances in fatty acid metabolism reprogramming of lung cancer [PDF]

Zhongguo aizheng zazhi, 2023
Lung cancer is the most common malignant tumor and the leading cause of cancer-related mortality. Although the development of targeted therapy and immunotherapy has significantly improved the efficacy and prognosis of lung cancer patients, the overall 5 ...
WU Jing, ZHOU Juan, SU Chunxia
doaj   +1 more source

Soybean Oil Regulates the Fatty Acid Synthesis II System of Bacillus amyloliquefaciens LFB112 by Activating Acetyl-CoA Levels

Microorganisms, 2023
[Background] Bacillus LFB112 is a strain of Bacillus amyloliquefaciens screened in our laboratory. Previous studies found that it has a strong ability for fatty acid metabolism and can improve the lipid metabolism of broilers when used as feed additives.
Qiang Cheng, Zhongxuan Li, Jing Zhang, Henan Guo, Marhaba Ahmat, Junhao Cheng, Zaheer Abbas, Zhengchang Hua, Junyong Wang, Yucui Tong, Tiantian Yang, Dayong Si, Rijun Zhang   +12 more
doaj   +1 more source

Fatty acid metabolism: A new therapeutic target for cervical cancer

Frontiers in Oncology, 2023
Cervical cancer (CC) is one of the most common malignancies in women. Cancer cells can use metabolic reprogramming to produce macromolecules and ATP needed to sustain cell growth, division and survival. Recent evidence suggests that fatty acid metabolism
Pengbin Ping, Juan Li, Hongbin Lei, Xiaoying Xu   +3 more
doaj   +1 more source

Plant oils were associated with low prevalence of impaired glucose metabolism in Japanese workers. [PDF]

PLoS ONE, 2013
Fatty acid has been suggested to be involved in development of diabetes. However, its association is unclear among Japanese populations, which consume large amounts of fish rich in n-3 polyunsaturated fatty acids.
Kayo Kurotani, Takeshi Kochi, Akiko Nanri, Hiroko Tsuruoka, Keisuke Kuwahara, Ngoc Minh Pham, Isamu Kabe, Tetsuya Mizoue   +7 more
doaj   +1 more source

Identification of subtypes of clear cell renal cell carcinoma and construction of a prognostic model based on fatty acid metabolism genes

Frontiers in Genetics, 2022
Background: The effects of fatty acid metabolism in many tumors have been widely reported. Due to the diversity of lipid synthesis, uptake, and transformation in clear cell renal cell carcinoma (ccRCC) cells, many studies have shown that ccRCC is ...
Shiwen Nie, Youlong Huili, Anliang Yao, Jian Liu, Yong Wang, Lei Wang, Liguo Zhang, Shaosan Kang, Fenghong Cao   +8 more
doaj   +1 more source

Fatty acids in cancer: Metabolic functions and potential treatment

MedComm – Oncology, 2023
Lipid metabolic reprogramming is one of the important metabolic characteristics of cancer cells. As major components of lipids, fatty acids provide energy and material basis for cancer cell survival.
Ao Du, Zhen Wang, Tengda Huang, Shuai Xue, Chuang Jiang, Guoteng Qiu, Kefei Yuan   +6 more
doaj   +1 more source