Results 131 to 140 of about 1,111,197 (376)

Dysregulated fatty acid metabolism in hepatocellular carcinoma.

Hepatic Oncology, 2016
Hepatocellular carcinoma (HCC) is one of the most frequent and deadly malignancies worldwide. Studies are urgently needed on its molecular pathogenesis and biological characteristics.
Mingda Wang, Jun Han, H. Xing, Han Zhang, Zhenli Li, L. Liang, Chao Li, S. Dai, Meng‐chao Wu, F. Shen, Tian Yang   +10 more
semanticscholar   +1 more source

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

FEBS Open Bio, EarlyView.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli, Andrea Spinaci, Cui Chang, Rosaria Volpini, Catia Lambertucci, Matteo Landriscina, Vincenza Conteduca, Consuelo Amantini, Cristina Aguzzi, Laura Zeppa, Martina Giangrossi, Laura Soverchia, Matteo Santoni, Massimo Nabissi, Giorgio Santoni, Carlo Polidori   +15 more
wiley   +1 more source

Reinforcement learning for robust dynamic metabolic control [PDF]

arXiv
Dynamic metabolic control can enhance bioprocess flexibility and expand the available optimization degrees of freedom via real-time modulation of metabolic enzyme expression. This allows target metabolic fluxes to be dynamically tuned throughout the process.
arxiv  

Quantification of Bone Fatty Acid Metabolism and Its Regulation by Adipocyte Lipoprotein Lipase

International Journal of Molecular Sciences, 2017
Adipocytes are master regulators of energy homeostasis. Although the contributions of classical brown and white adipose tissue (BAT and WAT, respectively) to glucose and fatty acid metabolism are well characterized, the metabolic role of adipocytes in ...
A. Bartelt, T. Koehne, K. Tödter, R. Reimer, B. Müller, F. Behler-Janbeck, J. Heeren, L. Scheja, A. Niemeier   +8 more
semanticscholar   +1 more source

SSO and other putative inhibitors of FA transport across membranes by CD36 disrupt intracellular metabolism, but do not affect FA translocation

Journal of Lipid Research, 2020
Membrane-bound proteins have been proposed to mediate the transport of long-chain FA (LCFA) transport through the plasma membrane (PM). These proposals are based largely on reports that PM transport of LCFAs can be blocked by a number of enzymes and ...
Anthony G. Jay, Jeffrey R. Simard, Nasi Huang, James A. Hamilton   +3 more
doaj  

Growth and instability of a phospholipid vesicle in a bath of fatty acids [PDF]

arXiv, 2016
Using a microfluidic trap, we study the behavior of individual phospholipid vesicles in contact with fatty acids. We show that spontaneous fatty acids insertion inside the bilayer is controlled by the vesicle size, osmotic pressure difference across the membrane and fatty acids concentration in the external bath. Depending on these parameters, vesicles
arxiv  

Fat Metabolism in Higher Plants. VII. β-Oxidation of Fatty Acids by Peanut Mitochondria. [PDF]

, 1956
P.K. Stumpf, G.A. Barber
openalex   +1 more source

Differences in elongation of very long chain fatty acids and fatty acid metabolism between triple-negative and hormone receptor-positive breast cancer

BMC Cancer, 2017
BackgroundTriple-negative breast cancer (TN) is more aggressive than other subtypes of breast cancer and has a lower survival rate. Furthermore, detailed biological information about the disease is lacking.
Y. Yamashita, S. Nishiumi, S. Kono, S. Takao, T. Azuma, Masaru Yoshida   +5 more
semanticscholar   +1 more source

Universal Proteomic Signature After Exercise‐Induced Muscle Injury in Muscular Dystrophies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Several neuromuscular disorders (NMDs) are characterized by progressive muscle damage and are marked by the elevation of circulating muscle proteins from activity‐related injury. Despite a diverse array of genetic drivers, many NMDs share similar patterns of exercise intolerance and higher concentrations of muscle injury proteins ...
Mads G. Stemmerik, Benjamin Barthel, Nanna R. Andersen, Sofie V. Skriver, Alan J. Russell, John Vissing   +5 more
wiley   +1 more source

SsCyp86 modulates Sporisorium scitamineum mating/filamentation and pathogenicity through regulating fatty acid metabolism

Virulence
Background Fatty acid metabolism constitutes a significant and intricate biochemical process within microorganisms. Cytochrome P450 (CYP450) enzymes are found in most organisms and occupy a pivotal position in the metabolism of fatty acids.
Enping Cai, Jiaru Deng, Ruqing Feng, Wenqiang Zheng, Yifang Wang, Meixin Yan, Changqing Chang   +6 more
doaj   +1 more source