Polyunsaturated fatty acids in the pathogenesis and treatment of multiple sclerosis [PDF]
, 2007 Epidemiological, biochemical, animal model and clinical trial data described in this overview strongly suggest that polyunsaturated fatty acids, particularly n-6 fatty acids, have a role in the pathogenesis and treatment of multiple sclerosis (MS).
Copeland +16 more
core +2 more sources
Enhancing microRNA167A expression in seed decreases the α-linolenic acid content and increases seed size in Camelina sativa. [PDF]
, 2019 Despite well established roles of microRNAs in plant development, few aspects have been addressed to understand their effects in seeds especially on lipid metabolism.
Grabowski, Paul +4 more
core +1 more source
Preeclampsia is associated with compromized maternal synthesis of long chain polyunsaturated fatty acids leading to offspring deficiency [PDF]
, 2012 Obesity and excessive lipolysis are implicated in preeclampsia (PE). Intrauterine growth restriction is associated with low maternal body mass index and decreased lipolysis.
Brown, E.A. +11 more
core +2 more sources
Three-year tracking of fatty acid composition of plasma phospholipids in healthy children [PDF]
, 2007 Objectives: The fatty acid composition of plasma phospholipids reflects the dietary fatty acid intake as well as endogenous turnover. We aimed at investigating the potential tracking of plasma phospholipid fatty acid composition in children that ...
Andersson A +35 more
core +1 more source
Lipids in Health and Disease, 2013 Background Lipid metabolism plays important roles in the whole process of pregnancy. Previous studies have demonstrated abnormalities of lipid metabolism in the placentas of pregnancies obtained by assisted reproductive technology (ART).
Wang Li-Ya +11 more
doaj +1 more source
Redirection of lipid flux toward phospholipids in yeast increases fatty acid turnover and secretion [PDF]
, 2018 Bio-based production of fatty acids and fatty acid-derived products can enable sustainable substitution of petroleum-derived fuels and chemicals. However, developing new microbial cell factories for producing high levels of fatty acids requires extensive
Ferreira, Raphael +3 more
core +1 more source
Epigenetic-Transcriptional Regulation of Fatty Acid Metabolism and Its Alterations in Leukaemia
Frontiers in Genetics, 2018 In recent years fatty acid metabolism has gained greater attention in haematologic cancers such as acute myeloid leukaemia. The oxidation of fatty acids provides fuel in the form of ATP and NADH, while fatty acid synthesis provides building blocks for ...
Michael Maher +4 more
doaj +1 more source
Foods, 2023 Alpha-linolenic acid (ALA, ω-3) is an antioxidant that reduces triglyceride (TG) levels in blood, a component of cell membranes and a precursor compound of eicosapentaenoic acid (EPA, ω-3) and eicosatrienoic acid (DHA, ω-3).
Wenjuan Zhao +6 more
doaj +1 more source
Plasma anandamide and other N-acylethanolamines are correlated with their corresponding free fatty acid levels under both fasting and non-fasting conditions in women [PDF]
, 2010 N-acylethanolamines (NAEs), such as anandamide (AEA), are a group of endogenous lipids derived from a fatty acid linked to ethanolamine and have a wide range of biological activities, including regulation of metabolism and food intake.
Balvers, M.G.J. +4 more
core +2 more sources
Key Molecules of Fatty Acid Metabolism in Gastric Cancer
Biomolecules, 2022 Fatty acid metabolism is closely linked to the progression of gastric cancer (GC), a very aggressive and life-threatening tumor. This study examines linked molecules, such as Sterol Regulatory Element-Binding Protein 1 (SREBP1), ATP Citrate Lyase (ACLY),
Chunlei Li +4 more
doaj +1 more source