Results 251 to 260 of about 499,256 (363)
Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development
Advanced Science, EarlyView.This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...Gang Chen, Zichen Liu, Mengyi Wei, Qian Li, Liang Wu, Kunyuan Yu, Yanhong Xu, Dainan Yu, Wenwu Ma, Hongmei Wang, Ng Shyh‐Chang, Jinglei Zhai +11 morewiley +1 more sourceMelatonin Alleviates High-Fructose-Induced Renal Injury in Male Mice, Which Might Be Associated with the Regulation of Mitophagy and Fatty Acid Oxidation. [PDF]
NutrientsMa Y, Sun D, Bai Y, Liu W, Bai X, Liu Z, Kong T, Wang P, Liang X, Zhang Z, Liang H, Zhang H. +11 moreeuropepmc +1 more sourceSupplementary Table S14 from C/EBPa confers dependence to fatty acid anabolic pathways and vulnerability to lipid oxidative stress-induced ferroptosis in FLT3-mutant leukemia
Marie Sabatier, Rudy Birsen, Laura Lauture, Sarah Mouche, Paolo Angelino, Jonas Dehairs, Léa Goupille, Ismael Boussaïd, Maël Heiblig, Emeline Boët, Ambrine Sahal, Estelle Saland, Juliana C. Santos, Marc Armengol, Miranda Fernández-Serrano, Thomas Farge, Guillaume Cognet, Federico Simonetta, Corentin Pignon, Antoine Graffeuil, Céline Mazzotti, Hervé Avet‐Loiseau, Océane Delos, Justine Bertrand‐Michel, Amélie Chedru, Vilma Dembitz, Paolo Gallipoli, Natasha S. Anstee, Sun Loo, Andrew H. Wei, Martin Carroll, Armelle Goubard, Rémy Castellano, Yves Collette, François Vergez, Véronique Mansat‐De Mas, Sarah Bertoli, Suzanne Tavitian, Muriel Picard, Christian Récher, Nathalie Bourgès‐Abella, Fanny Granat, Olivier Kosmider, Pierre Sujobert, Benoît Colsch, Carine Joffre, Lucille Stuani, Johannes V. Swinnen, Hervé Guillou, Gaël Roué, Nawad Hakim, Anne S. Dejean, Petros Tsantoulis, Clément Larrue, Didier Bouscary, Jérôme Tamburini, Jean‐Emmanuel Sarry +56 moreopenalex +1 more sourceTang-Nai-Kang Alleviates Pre-diabetes and Metabolic Disorders and Induces a Gene Expression Switch toward Fatty Acid Oxidation in SHR.Cg-Leprcp/NDmcr Rats
, 2015 Linyi Li, Hisae Yoshitomi, Ying Wei, Lingling Qin, Jingxin Zhou, Tunhai Xu, Xinli Wu, Tian Zhou, Wen Sun, Xiangyu Guo, Lili Wu, Haiyan Wang, Yan Zhang, Chunna Li, Tonghua Liu, Ming Gao +15 moreopenalex +2 more sourcesPeroxisome-derived lipids regulate adipose thermogenesis by mediating cold-induced mitochondrial fission [PDF]
, 2019 Agrawal, Anyuan He, Aranovich, Babak Razani, Baes, Braverman, Cohen, Dodt, Fong-Fu Hsu, Gould, Hongsuk Park, Irfan J. Lodhi, John M. Dean, Jordan M. Johnson, Katsuhiko Funai, Lim, Min Tan, Terri A. Pietka, Wikstrom, Xiangyu Zhang, Yali Chen +20 morecore +2 more sourcesDysfunctional TRIM31 of POMC Neurons Provokes Hypothalamic Injury and Peripheral Metabolic Disorder under Long‐Term Fine Particulate Matter Exposure
Advanced Science, EarlyView.Particulate matter ≤2.5 µm (PM2.5) elevates risks of neurological and chronic metabolic diseases, but the underlying mechanisms linking PM2.5‐induced central nervous system (CNS) injury to metabolic dysfunction remain unclear. Hypothalamic pro‐opiomelanocortin‐expressing (POMC+) neurons regulate systemic metabolic homeostasis, and tripartite motif ...Chenxu Ge, Jiamao Lin, Changsheng Yang, Chuanwang Miao, Fengxiang Li, Shuqiang Zhao, Lei Zou, Xuedong Teng, Lina Liu, Tingguang Li, Yan Sun, Qiang Li, Deshuai Lou, Linfeng Hu, Xi Liu, Gang Kuang, Jing Luo, Minxuan Xu, Minghui Chang, Jun Tan, Yanrong Ren, Bochu Wang +21 morewiley +1 more sourceTargeted Inhibition of CD74+ Macrophages by Luteolin via CEBPB/P65 Signaling Ameliorates Osteoarthritis Progression
Advanced Science, EarlyView.This study identifies CD74⁺ macrophages as key drivers of synovial inflammation in osteoarthritis (OA). The flavonoid luteolin is predicted to inhibit this pathway by blocking Nuclear Factor Kappa‐light‐chain‐enhancer of Activated B cells (NF‐κB) signaling. To enhance delivery, a targeted nanoplatform (MDSPL) is developed.Rui Peng, Bo Yu, Lei Zhang, Zhaowen Xue, Lutian Yao, Qingjun Yang, Zitao Liu, Sizhi Wu, Yongquan Huang, Xiaofei Zheng, Huiying Guo, Songwei Huan, Tao Jiang, Huajun Wang, Yulong Wei, Tao Gui +15 morewiley +1 more source
