Results 261 to 270 of about 499,256 (363)

Single‐Cell Metabolic Imaging Reveals Glycogen‐Driven Adaptations in Endothelial Cells

Advanced Science, EarlyView.
Single‐cell metabolic imaging of diabetes‐associated endothelial dysfunction by SRS microscopy reveals dynamic glycogen storage and its role in modulating metabolic adaptations under glucose starvation. Abstract Endothelial dysfunction (ED) is a defining feature of diabetes mellitus (DM) and a key contributor to many metabolic and cardiovascular ...
Rahuljeet S. Chadha, Benjamin Yang, Dongqiang Yuan, Edmund D. Kapelczak, Philip A. Kocheril, Alonso Tapia, Shivansh Mahajan, Adrian Colazo, Naseeb K. Malhi, Joseph A. Ambarian, Xuejing Liu, Tara A. TeSlaa, Zhen B. Chen, Lu Wei   +13 more
wiley   +1 more source

Effects of Maternal Clofibrate Supplementation During Gestation and Lactation on Intestinal Fatty Acid Oxidation of Suckling Piglets. [PDF]

Int J Mol Sci
Pike B, Zhao J, Hicks JA, Wang F, Meisner P, Yang L, Liu HC, Odle J, Lin X.   +8 more
europepmc   +1 more source

Importance of fatty acid desaturation in tumor growth and oxidative stress response occurring during antiangiogenic treatment

, 2016
Géraldine Luis, Adrien Godfroid, Silvia Blacher, Agnès Noël, Nor Eddine Sounni, Jonathan Cimino, Shin Nishiumi, Masaru Yoshida   +7 more
openalex   +1 more source

High Fat Diet Upregulates Fatty Acid Oxidation and Ketogenesis via Intervention of PPAR-γ

, 2018
Kunal Sikder, Sanket K. Shukla, Neel Patel, Harpreet Singh, Khadija Rafiq   +4 more
openalex   +1 more source

A Methodology for Deciphering the Transmembrane Resistance Variability of Supported Lipid Bilayers

Advanced Science, EarlyView.
This work shows that transmembrane resistance variability, due to lipid packing defects, can be quantified by analysing the dielectric properties of Supported Lipid Bilayers. The proposed methodology provides an analytical tool for optimizing SLB design with improved stability and functionality for bioelectronic and biomimetic applications. Abstract In
Aristea Pavlou, Debdatta Panigrahi, Somayeh Kashani, Anna‐Maria Pappa, Fabrizio Torricelli, Paul W.M. Blom, Paschalis Gkoupidenis   +6 more
wiley   +1 more source

Acute exogenous acyl-GIP treatment enhances lipid handling and fatty acid oxidation by involving brown fat. [PDF]

EMBO Rep
Lyons SA, Lea MBS, Parikh M, Guo Z, Kagdi S, Bisnauth AR, Pitino JR, Ziai S, Mir N, Tyrrell AD, Fu Y, Chen CT, Metherel AH, Bazinet RP, Yang B, Knerr PJ, Douros JD, Campbell JE, Beaudry JL.   +18 more
europepmc   +1 more source

Exclusive Breastfeeding Drives AMPK‐Dependent Thermogenic Memory in BAT and Promotes Long‐Term Metabolic Benefits in Offspring

Advanced Science, EarlyView.
Exclusive breastfeeding establishes a thermogenic memory in brown adipose tissue by activating the HIF1AN/AMPK/α‐ketoglutarate axis via milk‐derived extracellular vesicles enriched in miR‐125a‐5p. This programming preserves metabolic health, while αKG supplementation restores BAT function under mixed feeding, offering strategies to mitigate the ...
Ningxi Wu, Anwen Yin, Xiang Yu, Mingxin Wang, Jiahui Zhang, Kerong Liu, Yutong Hou, Minkai Cao, Yiting Zhang, Xiaoxiao Zhang, Yao Gao, Xirong Guo, Le Zhang, Yun Li   +13 more
wiley   +1 more source

Roxadustat alleviates cisplatin-induced acute kidney injury by regulating fatty acid oxidation and mitochondrial function. [PDF]

Ren Fail
Li X, Hu Y, Li J, Shi Y, Zhong Q, Ma X, Jiang D, Zhang S, Zhuang S, Liu N.   +9 more
europepmc   +1 more source

Redox‐Responsive Tellurium‐Bridged Covalent Organic Frameworks/PEG Composites for Targeted Therapy of Diabetic Cardiomyopathy

Advanced Science, EarlyView.
This study unlocks the immense potential of COF@polymer nanocomposites as a multifunctional therapeutic platform for targeted drug delivery in diabetic cardiomyopathy. Abstract Diabetic cardiomyopathy, a major complication of diabetes, is strongly associated with elevated levels of glycated hemoglobin (HbA1c) and reactive oxygen species (ROS). However,
Jing Xue, Jialu Zhuang, Taotao Fan, Songtao Tang, Junjun Wang, Xiaohui Liu, Jian Liu, Jin Shi, Jiaji Li, Wanjun Li, Danyou Hu, Xiaoqian Zhang, Hua Wang, Guiyang Zhang   +13 more
wiley   +1 more source

Cytoskeleton Rearrangement Decreases Mitochondrial Fatty Acid Oxidation in Renal Tubular Epithelial Cells Contributing to Renal Fibrogenesis. [PDF]

Drug Des Devel Ther
Wang G, Li Y, Wan X, Wang Y, Niu H, Tan E, Niu S, Feng X, Hou Y, Wang L.   +9 more
europepmc   +1 more source